Zobrazeno 1 - 10
of 187
pro vyhledávání: '"YOSHIKO NAKAMURA"'
Autor:
Yusuke Okujima, Takao Watanabe, Takeshi Ito, Yasumichi Inoue, Yutaka Kasai, Yusuke Imai, Yoshiko Nakamura, Mitsuhito Koizumi, Osamu Yoshida, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Ryosuke Kawakami, Takashi Saitou, Takeshi Imamura, Yoshinori Murakami, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract RNA-dependent protein kinase (PKR) may have a positive regulatory role in controlling tumor growth and progression in hepatocellular carcinoma (HCC). However, the downstream substrates and the molecular mechanism of PKR in the growth and pro
Externí odkaz:
https://doaj.org/article/dd42980cfe6a449483d6c8e426e3ad7c
Autor:
Teruki Miyake, Shinya Furukawa, Bunzo Matsuura, Osamu Yoshida, Masumi Miyazaki, Akihito Shiomi, Ayumi Kanamoto, Hironobu Nakaguchi, Yoshiko Nakamura, Yusuke Imai, Mitsuhito Koizumi, Takao Watanabe, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Teru Kumagi, Eiji Takesita, Yoshio Ikeda, Masanori Abe, Yoichi Hiasa
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 3, Pp 440-448 (2024)
Background Poor lifestyle habits may worsen nonalcoholic fatty liver disease (NAFLD), with progression to nonalcoholic steatohepatitis (NASH) and cirrhosis. This study investigated the association between glycemic control status and hepatic histologi
Externí odkaz:
https://doaj.org/article/0799ea71104b4e77bcf45e6604848a54
Autor:
Masashi Hirooka, Yohei Koizumi, Ryo Yano, Yoshiko Nakamura, Koutarou Sunago, Atsushi Yukimoto, Takao Watanabe, Osamu Yoshida, Yoshio Tokumoto, Masanori Abe, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract For patients with cirrhosis, no definitive predictor of the efficacy and prognosis of tolvaptan treatment exists. We assessed the cisterna chyli’s utility as an optimal marker. We retrospectively enrolled 172 patients with cirrhosis. The e
Externí odkaz:
https://doaj.org/article/15304c9f38ce487fb49de95aaf7bf265
Autor:
Teruki Miyake, Bunzo Matsuura, Shinya Furukawa, Osamu Yoshida, Masashi Hirooka, Teru Kumagi, Toru Ishihara, Sayaka Kanzaki, Hironobu Nakaguchi, Masumi Miyazaki, Yoshiko Nakamura, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Eiji Takeshita, Yoshio Ikeda, Masanori Abe, Kohichiro Kitai, Yoichi Hiasa
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 10, Pp 1890-1898 (2021)
Abstract Introduction Fatty liver disease (FLD) is a surrogate condition for glucose intolerance development. FLD may involve normal or abnormal liver enzyme levels. Whether FLD is a risk factor for glucose intolerance, regardless of liver enzyme lev
Externí odkaz:
https://doaj.org/article/eb2dc624ac084aec8623e13bdb471950
Autor:
Masashi Hirooka, Yohei Koizumi, Takaaki Tanaka, Kotarou Sunago, Yoshiko Nakamura, Takao Watanabe, Osamu Yoshida, Yoshio Tokumoto, Masanori Abe, Yoichi Hiasa
Publikováno v:
Hepatology Communications, Vol 5, Iss 7, Pp 1300-1309 (2021)
Hepatocellular carcinoma has been considered to disseminate through the tumor blood drainage area. To improve curation rates, treatment should cover this area as it may contain satellite lesions. This retrospective study aimed to investigate whether
Externí odkaz:
https://doaj.org/article/6bf20d1af0824ce38c7ee0126a816122
Autor:
Teruki Miyake, Masumi Miyazaki, Osamu Yoshida, Sayaka Kanzaki, Hironobu Nakaguchi, Yoshiko Nakamura, Takao Watanabe, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Shinya Furukawa, Eiji Takeshita, Teru Kumagi, Yoshio Ikeda, Masanori Abe, Kumiko Toshimitsu, Bunzo Matsuura, Yoichi Hiasa
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Causes of non-alcoholic fatty liver disease and its progression include visceral fat accumulation and loss of muscle mass; however, which of the two phenomena is more critical is unclear. Therefore, we intended to examine the rela
Externí odkaz:
https://doaj.org/article/54c59556fa5e4a97abd0ad3f81e13b82
Autor:
Atsushi Yukimoto, Takao Watanabe, Kotaro Sunago, Yoshiko Nakamura, Takaaki Tanaka, Yohei Koizumi, Osamu Yoshida, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Endoplasmic reticulum (ER) stress plays an important role in hepatocyte degeneration, especially in patients with chronic liver injury. Protein kinase R-like endoplasmic reticulum kinase (PERK) is a key molecule in ER stress. PERK may contri
Externí odkaz:
https://doaj.org/article/c81affd535aa44499e9b9374cdcaecf6
Autor:
Tomoe Kinoshita, Masashi Shimoda, Koji Nakashima, Yoshiro Fushimi, Yurie Hirata, Akihito Tanabe, Fuminori Tatsumi, Hidenori Hirukawa, Junpei Sanada, Kenji Kohara, Shintaro Irie, Tomohiko Kimura, Yoshiko Nakamura, Momoyo Nishioka, Atsushi Obata, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 6, Pp 1612-1622 (2020)
Abstract Aims/Introduction Non‐alcoholic fatty liver disease (NAFLD) is often observed in individuals with type 2 diabetes mellitus, and it is known that the presence of type 2 diabetes mellitus leads to the aggravation of NAFLD. The aim of this st
Externí odkaz:
https://doaj.org/article/a18ca58a66754a8ea9d638264267d1ea
Autor:
Teruki Miyake, Shinya Furukawa, Bunzo Matsuura, Osamu Yoshida, Masumi Miyazaki, Akihito Shiomi, Sayaka Kanzaki, Hironobu Nakaguchi, Kotaro Sunago, Yoshiko Nakamura, Yusuke Imai, Takao Watanabe, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Teru Kumagi, Masanori Abe, Yoichi Hiasa
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2540 (2022)
The relationship between advanced nonalcoholic steatohepatitis (NASH) and plasma fatty acid composition remains unknown. We aimed to examine the plasma fatty acid composition in biopsy-confirmed nonalcoholic fatty liver disease (NAFLD) and evaluate t
Externí odkaz:
https://doaj.org/article/cea1cd6a850c43b9b67f5b8c2dae8a91
Autor:
Takaaki Tanaka, Masashi Hirooka, Yohei Koizumi, Takao Watanabe, Osamu Yoshida, Yoshio Tokumoto, Yoshiko Nakamura, Koutarou Sunago, Atsushi Yukimoto, Masanori Abe, Yoichi Hiasa
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246315 (2021)
BackgroundHepatic venous pressure gradient (HVPG) is the gold standard index for evaluating portal hypertension; however, measuring HVPG is invasive. Although transient elastography (TE) is the most common procedure for evaluating organ stiffness, ac
Externí odkaz:
https://doaj.org/article/e33bd7dad93e4b2ba3cca173e45323de