Zobrazeno 1 - 10
of 424
pro vyhledávání: '"YOSHIHIRO KOMOHARA"'
Autor:
Hiroaki Matsuzaki, Cheng Pan, Yoshihiro Komohara, Rin Yamada, Hiromu Yano, Yukio Fujiwara, Keitaro Kai, Akitake Mukasa
Publikováno v:
Immunological Medicine, Pp 1-9 (2024)
Glioblastoma (GBM) is the central nervous system tumor with the most aggressive behavior, and no definitive therapy has yet been found. The tumor microenvironment of GBM is immunosuppressive and is considered a ‘cold tumor’ with low lymphocytic i
Externí odkaz:
https://doaj.org/article/d0dd0c50717242e79bb05cd3a1956b70
Publikováno v:
Thoracic Cancer, Vol 15, Iss 18, Pp 1429-1436 (2024)
Abstract Background Photodynamic therapy (PDT) is an antitumor therapy and has traditionally been regarded as a localized therapy in itself. However, recent reports have shown that it not only exerts a direct cytotoxic effect on cancer cells but also
Externí odkaz:
https://doaj.org/article/430f5378a6224673b0b4cb46feb2abb2
Autor:
Ryota TASHIRO, Kazushi MIYAMOTO, Yoshiyuki KUME, Ryo SUZUKI, Yukio FUJIWARA, Yoshihiro KOMOHARA, Yuta NAKASHIMA, Yoshitaka NAKANISHI
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 19, Iss 4, Pp 24-00040-24-00040 (2024)
Micro/nanoplastics (MPs/NPs) in the environment exhibit various effects on ecosystems as well as living organisms, such as immune system toxicity. To understand the effects of MPs/NPs experimentally, preparing synthetic MPs/NPs with their geometrical
Externí odkaz:
https://doaj.org/article/39986979a0b746789bfe1b26b532b198
Autor:
Rikito Tatsuno, Jiro Ichikawa, Yoshihiro Komohara, Cheng Pan, Tomonori Kawasaki, Atsushi Enomoto, Kaoru Aoki, Keiko Hayakawa, Shintaro Iwata, Takahiro Jubashi, Hirotaka Haro
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-13 (2024)
Abstract The prognosis of osteosarcoma (OS) has remained stagnant over the past two decades, requiring the exploration of new therapeutic targets. Cytokines, arising from tumor-associated macrophages (TAMs), a major component of the tumor microenviro
Externí odkaz:
https://doaj.org/article/f5d0dc329a314cc4bfe6ab4e99f3b262
Autor:
Hitoshi Fukase, Munenori Honda, Hideaki Miyamoto, Masatoshi Nakashima, Ryosuke Gushima, Hideaki Naoe, Rin Yamada, Yoshihiro Komohara, Yasuhito Tanaka
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Cronkhite‐Canada syndrome (CCS) is a rare disease characterized by gastrointestinal polyposis, skin pigmentation, alopecia, and abnormal nailfolds. Although colorectal cancer has been reported in patients with CCS, reports are limited rega
Externí odkaz:
https://doaj.org/article/565c33db05f645e89f1e979145a6b58d
Autor:
Hiroki Iwata, Hidehito Maeda, Kengo Tsuneyoshi, Takuma Matsumoto, Hiroshi Fujita, Yoshihiro Komohara, Akio Ido
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract A 77‐year‐old male patient underwent esophagogastroduodenoscopy at his family doctor, and an easily hemorrhagic depressed lesion was noted near the anterior wall of the gastric antrum. A biopsy revealed moderately differentiated tubular
Externí odkaz:
https://doaj.org/article/647f984940b7402f97e13ad1bba6e472
Autor:
Rikito Tatsuno, Jiro Ichikawa, Yoshihiro Komohara, Cheng Pan, Tomonori Kawasaki, Atsushi Enomoto, Kaoru Aoki, Keiko Hayakawa, Shintaro Iwata, Takahiro Jubashi, Hirotaka Haro
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/29cdfbeb454d46dbb9a10b0b3f45f6b6
Autor:
Cheng Pan, Yukio Fujiwara, Hiromu Yano, Toshiki Anami, Yuki Ibe, Lianbo Li, Yuji Miura, Takanobu Motoshima, Shigeyuki Esumi, Junji Yatsuda, Taizo Hibi, Tomomi Kamba, Yoshihiro Komohara
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Objectives C‐reactive protein (CRP) is a well‐known acute‐phase protein that increases remarkably under various inflammatory conditions and is elevated in patients with malignant tumors. In this study, we investigated the influence of
Externí odkaz:
https://doaj.org/article/9621d11915cf40d18cdc4f89fa59a864
Autor:
Yoichi Saito, Yukio Fujiwara, Yuji Miyamoto, Koji Ohnishi, Yuta Nakashima, Yasuhiko Tabata, Hideo Baba, Yoshihiro Komohara
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10199-10211 (2023)
Abstract Aims Mismatch‐repair deficiency and microsatellite instability‐high (dMMR/MSI‐H) colorectal cancer (CRC) is treated with programmed death (PD)‐1 antibody regardless of PD‐ligand (L)1 expression in tumor cells. We previously found t
Externí odkaz:
https://doaj.org/article/85c9c1f64bac4835bef398c08bc6d691
Autor:
Ami Oguro, Taichi Fujiyama, Yasuhiro Ishihara, Chisato Kataoka, Megumi Yamamoto, Komyo Eto, Yoshihiro Komohara, Susumu Imaoka, Toshihide Sakuragi, Mayumi Tsuji, Eiji Shibata, Yaichiro Kotake, Takeshi Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100458- (2023)
Although pregnant women’s fish consumption is beneficial for the brain development of the fetus due to the DHA in fish, seafood also contains methylmercury (MeHg), which adversely affects fetal brain development. Epidemiological studies suggest tha
Externí odkaz:
https://doaj.org/article/e92ba8be57fa4b2ea88b871630551256