Zobrazeno 1 - 10
of 42
pro vyhledávání: '"YOSHIHIKO ICHIKAWA"'
Autor:
Ryosuke Ono, Kenichi Furihata, Yoshihiko Ichikawa, Yoshiomi Nakazuru, Arthur Bergman, Donal N. Gorman, Aditi R. Saxena
Publikováno v:
Diabetes, Obesity and Metabolism. 25:805-814
Autor:
Ryosuke, Ono, Kenichi, Furihata, Yoshihiko, Ichikawa, Yoshiomi, Nakazuru, Arthur, Bergman, Donal N, Gorman, Aditi R, Saxena
Publikováno v:
Diabetes, obesitymetabolismREFERENCES.
This study investigated the safety, tolerability, pharmacokinetics and pharmacodynamics of danuglipron (PF-06882961), which is a novel, oral small-molecule glucagon-like peptide-1 receptor agonist, in Japanese participants with type 2 diabetes mellit
Autor:
RYOSUKE ONO, KENICHI FURIHATA, YOSHIHIKO ICHIKAWA, YOSHIOMI NAKAZURU, ARTHUR BERGMAN, DONAL N. GORMAN, ADITI R. SAXENA
Publikováno v:
Diabetes. 71
Danuglipron is an oral small molecule glucagon-like peptide-1 receptor (GLP-1R) agonist shown to reduce plasma glucose and body weight after 28 days of treatment in adults with type 2 diabetes mellitus (T2DM) . This randomized, double-blind (sponsor-
Publikováno v:
SSRN Electronic Journal.
This paper investigates a hedge and safe haven asset for Bitcoin investors. Bitcoin has been receiving high attention from finance investors because of its high upside return and volatility. The recent finance literature focused upon Bitcoin characte
Autor:
Masafumi Yano, Toyoaki Murohara, Kazuhiro Kanmuri, Hiroshi Ito, Issei Komuro, Kazuhiro Yamamoto, Junwei Zhang, Masunori Matsuzaki, Yoshihiko Ichikawa, Yoshio Yasumura, Tsutomu Yoshikawa, Kenji Sunagawa, Tohru Izumi, Takayoshi Tsutamoto, Masafumi Kitakaze, Akifumi Okayama, Hiroyuki Tsutsui
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 82(1)
BACKGROUND The mineralocorticoid receptor antagonist eplerenone improved clinical outcomes among patients with heart failure with reduced ejection faction (HFrEF) in the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in H
Autor:
Yoshihiko Ichikawa
Publikováno v:
Internal Medicine. 46:1331-1336
Objective Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that includes hyperglycemia, dyslipidemia, hypertension and increased waist circumference. Individuals with this syndrome are at increased risk for development of cardiovascu
Autor:
Masahiro Nishihara, Yoshihiko Ichikawa, Yuichi Nakamura, Yoshihiro Ikeda, Hironori Kobayashi, Tetsuji Miura, Takayuki Miki, Katsuhiko Ohori, Kazuaki Shimamoto, Kazuyuki Naitoh
Publikováno v:
Cardiovascular Research. 70:374-383
Ischemic preconditioning accelerates suppression of gap junction (GJ) permeability during myocardial ischemia, and GJ blockers reduce infarct size. We hypothesized that the mitochondrial ATP-sensitive K+ (mitoKATP) channel is one of the mechanisms re
Autor:
Toshiyuki Yano, Katsuhiko Ohori, Hironori Kobayashi, Jun Sakamoto, Yoshihiro Ikeda, Kazuaki Shimamoto, Yoshihiko Ichikawa, Tetsuji Miura, Peter Whittaker, Yuichi Nakamura, Takayuki Miki
Publikováno v:
Journal of the American College of Cardiology. 47(3):626-634
Objectives We aimed to determine the effects of macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF) treatment on both the repair process and ventricular function after myocardial infarction (MI). Background
Autor:
Nobuyuki Ura, Yoshihiro Ikeda, Yoshihiko Ichikawa, Hironori Kobayashi, Tetsuji Miura, Yuichi Nakamura, Kazuaki Shimamoto, Takayuki Miki, Jun Sakamoto, Yasuhiro Nishino, Toshiyuki Yano
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 31:873-882
1. The aim of the present study was to examine the effects of mobilization of bone marrow cells by granulocyte colony stimulating factor (G-CSF) and macrophage colony stimulating factor (M-CSF) on ventricular function after myocardial infarction (MI)
Autor:
Toshiyuki Yano, Jun Sakamoto, Yuichi Nakamura, Kazuaki Shimamoto, Atsushi Kuno, Tetsuji Miura, Masaya Tanno, Takayuki Miki, Yoshito Ohnuma, Yoshihiko Ichikawa
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 286:H214-H221
The aim of the present study was to examine the hypothesis that acceleration of gap junction (GJ) closure during ischemia contributes to anti-infarct tolerance afforded by preconditioning (PC). First, the effects of PC on GJ communication during isch