Zobrazeno 1 - 10
of 60
pro vyhledávání: '"YONGYAN DANG"'
Publikováno v:
Nutrients, Vol 15, Iss 3, p 694 (2023)
Hordenine is effective in treating hyperpigmentation, fighting diabetes and resisting fibrosis and acute inflammation. However, the role of Hordenine on hair growth has not been elucidated. Here, we found that Hordenine treatments significantly enhan
Externí odkaz:
https://doaj.org/article/c494e034314b4093818b33189b0d2214
Autor:
Jinjin Xu, Lei Zhou, Lei Ji, Fengyuan Chen, Karen Fortmann, Kun Zhang, Qingwu Liu, Ke Li, Weicang Wang, Hao Wang, Wei Xie, Qingwei Wang, Jiang Liu, Biao Zheng, Pei Zhang, Shixia Huang, Tieliu Shi, Biaohong Zhang, Yongyan Dang, Jiwu Chen, Bert W. O’Malley, Robb E. Moses, Ping Wang, Lei Li, Jianru Xiao, Alexander Hoffmann, Xiaotao Li
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
REGγ is a component of ubiquitin-independent 20S proteasome that targets many regulatory proteins for degradation. Here the authors show that REGγ is induced in DSS colitis and promotes degradation of IκBɛ, and that REGγ-deficient mice have less
Externí odkaz:
https://doaj.org/article/815ed3c7811843c397e9095adc1ff9cf
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89835 (2014)
G protein-coupled receptor 48 (Gpr48/Lgr4) is essential to regulate the development of multiple tissues in mice. The notion that Gpr48 functions in renal development prompted us to investigate the relation between Gpr48 and renal diseases. Using a Gp
Externí odkaz:
https://doaj.org/article/9d2eea9b1ea34ffa89b389235d440f48
Publikováno v:
Journal of Diabetes Research, Vol 2013 (2013)
Background. The notion that diabetic nephropathy is the leading cause of renal fibrosis prompted us to investigate the effects of blood glucose fluctuation (BGF) under high glucose condition on kidney in the mice. Methods. The diabetic and BGF animal
Externí odkaz:
https://doaj.org/article/900fd246a1c44daf82fb62f9b79c17f1
Publikováno v:
Journal of Dermatological Science. 107:17-23
Yohimbine hydrochloride (YH) is a prescription drug to treat erectile dysfunction. It also had potential in fighting high blood pressure and diabetic neuropathy as well as promoting weight loss.The aim of the study is to investigate the anti-melanoge
Autor:
Xiaotao Li, Yongyan Dang, Lei Li, Jianru Xiao, Junjiang Fu, Fengyuan Chen, Jianhua Yang, Robb E. Moses, Pei Zhang, Long Cui, Quan Huang, Wang Zhou, Chan Jiao, Geng Chen, Weicang Wang, Jie Dai, Lei Yuan, Tong Yu, Xiao Gao, Qingwei Wang
Supplementary Figure1-10, Table1-2 Figure S1. The relations of REGγ with Hippo-YAP signal pathway in colon cancer. A. The protein levels of Lats2 and p-Lats1 were unchanged in HCT116 and HT29 human colon cancer cells with REGγ knockdown. The ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a42709953f50ea786597df3644f046
https://doi.org/10.1158/1078-0432.22465626
https://doi.org/10.1158/1078-0432.22465626
Autor:
Xiaotao Li, Yongyan Dang, Lei Li, Jianru Xiao, Junjiang Fu, Fengyuan Chen, Jianhua Yang, Robb E. Moses, Pei Zhang, Long Cui, Quan Huang, Wang Zhou, Chan Jiao, Geng Chen, Weicang Wang, Jie Dai, Lei Yuan, Tong Yu, Xiao Gao, Qingwei Wang
Purpose: Colorectal cancer is one of the most commonly diagnosed cancers closely associated with inflammation and hyperactive growth. We previously demonstrated a regulatory circuit between the proteasome activator REGγ and NF-kappaB (NF-κB) during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a32f8befc6f210cc25f3f5a70dbe7c5
https://doi.org/10.1158/1078-0432.c.6525890.v1
https://doi.org/10.1158/1078-0432.c.6525890.v1
Autor:
Lei Li, Peng Xu, Yongyan Dang, Jianru Xiao, Xiaoshuang Wang, Ying Yu, Lei Yuan, Zhipeng Wu, Qingwei Wang, Chan Jiao, Xiao Gao, Yining Ma, Yelin Wu
Publikováno v:
Journal of Dermatological Science. 102:101-108
Background REGγ acts as a proteasome activating factor mediating proteasome degradation of substrate proteins in an ATP and ubiquitination independent manner and also as an important regulator of cell cycle, proliferation and apoptosis. Hair cycle i
Publikováno v:
Journal of Cosmetic Science; May/Jun2023, Vol. 74 Issue 3, p158-172, 15p, 1 Chart
Autor:
Peng Xu, Caibing Wang, Wan Xiang, Yiyi Liang, Ying Li, Xilin Zhang, Chunyuan Guo, Mingyao Liu, Yuling Shi, Xiyun Ye, Yongyan Dang
Publikováno v:
Journal of Investigative Dermatology. 142:2334-2342.e8
P2RY6 is highly expressed in skin keratinocytes, but its function in skin diseases is unclear. We use a two-step chemical induction method to induce mouse skin tumor formation. Multiple in vitro and in vivo assays were used to explore the role of P2R