Zobrazeno 1 - 10
of 55
pro vyhledávání: '"YONGLONG GUO"'
Autor:
Wenxuan Wang, Tingting Yang, Sihui Chen, Liying Liang, Yingxin Wang, Yin Ding, Wei Xiong, Xiuhong Ye, Yonglong Guo, Shuhao Shen, Hang Chen, Jiansu Chen
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-18 (2024)
Abstract Background Retinal pigment epithelium (RPE) cell therapy is a promising way to treat many retinal diseases. However, obtaining transplantable RPE cells is time-consuming and less effective. This study aimed to develop novel strategies for ge
Externí odkaz:
https://doaj.org/article/be57c34246944a45817a587af32202f4
Autor:
Xiangqin Tian, Yangyang Jia, Yonglong Guo, Hongyin Liu, Xinhua Cai, Yong Li, Zhuangzhuang Tian, Changye Sun
Publikováno v:
FEBS Open Bio, Vol 13, Iss 10, Pp 1895-1909 (2023)
Fibroblast growth factor (FGF) signaling plays a crucial role in lung development and repair. Fibroblast growth factor 2 (FGF2) can inhibit fibrotic gene expression and suppress the differentiation of pulmonary fibroblasts (PFs) into myofibroblasts i
Externí odkaz:
https://doaj.org/article/da1621d7674c4e22aed4950b8a41a902
Publikováno v:
PeerJ, Vol 11, p e15736 (2023)
After myocardial injury, cardiac fibroblasts (CFs) differentiate into myofibroblasts, which express and secrete extracellular matrix (ECM) components for myocardial repair, but also promote myocardial fibrosis. Recombinant fibroblast growth factor 2
Externí odkaz:
https://doaj.org/article/80adbd67345b49cab1226e125c736fc3
Autor:
Luyin Chen, Jianing Wang, Tingting Yang, Linyao Xie, Zekai Cui, Quan Yu, Jingxiang Zhong, Hon fai Chan, Yunxia Xue, Yonglong Guo, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 68, Iss , Pp 103055- (2023)
We generated an induced pluripotent stem (iPS) cell line by reprogramming peripheral blood mononuclear cells of a patient with Usher syndrome type II carrying USH2A gene mutation (c.8559-2A > G). The iPS cell line with confirmed patient-specific poin
Externí odkaz:
https://doaj.org/article/92e862083d8e4877b8f08e38fb3958da
Autor:
Deliang Zhu, Mengyuan Xie, Fabian Gademann, Jixing Cao, Peiyuan Wang, Yonglong Guo, Lan Zhang, Ting Su, Jun Zhang, Jiansu Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/e6d3d915b859464dbd5eb676b0c9c9fb
Autor:
Ting Su, Liying Liang, Lan Zhang, Jianing Wang, Luyin Chen, Caiying Su, Jixing Cao, Quan Yu, Shuai Deng, Hon Fai Chan, Shibo Tang, Yonglong Guo, Jiansu Chen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Retinitis pigmentosa (RP) is a leading cause of vision impairment and blindness worldwide, with limited medical treatment options. USH2A mutations are one of the most common causes of non-syndromic RP. In this study, we developed retinal organoids (R
Externí odkaz:
https://doaj.org/article/48118f4b207649a0aa8ef21185b5bed1
Autor:
Deliang Zhu, Mengyuan Xie, Fabian Gademann, Jixing Cao, Peiyuan Wang, Yonglong Guo, Lan Zhang, Ting Su, Jun Zhang, Jiansu Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Retinitis pigmentosa (RP) is an inherited retinal disease characterized by progressive loss of photoreceptor cells. This study aim at exploring the effect of retinal pigment epithelium (RPE) derived from human-induced pluripotent
Externí odkaz:
https://doaj.org/article/5f6ba9add0fa46c483636b7fc1739585
Autor:
Liying Liang, Yunxia Xue, Caiying Su, Jianing Wang, Luyin Chen, Ting Su, Jianyu Ke, Linyao Xie, Zekai Cui, Quan Yu, Hon fai Chan, Jingxiang Zhong, Yonglong Guo, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102699- (2022)
USH type 2 (USH2) is an autosomal recessive disorder that is characterized by inherited retinopathies and sensorineural hearing loss. USH type 2 (USH2) is frequently caused by USH2A mutations, which account for 74–90% of USH2 cases. We used periphe
Externí odkaz:
https://doaj.org/article/7343b4364b1041809eb3a0933de3a4f1
Autor:
Shenyang Li, Chengcheng Ding, Yonglong Guo, Yanan Zhang, Hao Wang, Xihao Sun, Jun Zhang, Zekai Cui, Jiansu Chen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported to effect corneal fibroblast reprogramming. Polydimethylsiloxane (PDMS), with hydrophobic and soft substrate properties, facilitates adherent spheroid formation that prom
Externí odkaz:
https://doaj.org/article/4380792a027948029ee855fb390d5c8f
Autor:
Shengru Mao, Chengcheng Ding, Yalan Zhou, Yutong Jing, Juan Chen, Yonglong Guo, Jian Liu, Zekai Cui, Xin Yan, Jianing Gu, Yini Wang, Jiansu Chen, Shibo Tang
Publikováno v:
Stem Cell Research, Vol 43, Iss , Pp - (2020)
X-linked retinoschisis (XLRS) is a one of most common retinal genetic diseases of juvenile progressive vitreoretinal degeneration in males, which caused by the mutation of RS1 gene. In this study, an induced pluripotent stem cell (iPSC) line was gene
Externí odkaz:
https://doaj.org/article/850084e7ef8e4cd298f9e0c42f820924