Zobrazeno 1 - 10
of 57
pro vyhledávání: '"YONG‑SEOK HAN"'
Autor:
Yong-Seok Han, Seung Pil Yun, Jun Hee Lee, Seung-Hwan Kwon, SangMin Kim, Jin Hur, Sang Hun Lee
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 5, Pp 1835-1848 (2018)
Background/Aims: Stem cell transplantation has emerged as a promising therapeutic strategy, but the exact mechanisms by which stem cells exposed to hypoxic conditions increase the survival rate and rescue ischemic injury at the graft site are not wel
Externí odkaz:
https://doaj.org/article/6f478c8c53f24bfe85db2d57b4694dd6
Autor:
Yeo Min Yoon, SangMin Kim, Yong-Seok Han, Chul Won Yun, Jun Hee Lee, Hyunjin Noh, Sang Hun Lee
Publikováno v:
Redox Biology, Vol 22, Iss , Pp - (2019)
Although autologous human mesenchymal stem cells (hMSCs) are a promising source for regenerative stem cell therapy in chronic kidney disease (CKD), the barriers associated with pathophysiological conditions limit therapeutic applicability to patients
Externí odkaz:
https://doaj.org/article/b340e35563ad4f2bb3447894ff80eb26
Publikováno v:
Marine Drugs, Vol 17, Iss 9, p 518 (2019)
Mitochondria are considered to be the powerhouses of cells. They are the most commonly damaged organelles within dopaminergic neurons in patients with Parkinson’s disease (PD). Despite the importance of protecting neuronal mitochondria in PD patien
Externí odkaz:
https://doaj.org/article/a50db2a4fcb94547809c7d8d43fe7ff3
Publikováno v:
Prostate International, Vol 9, Iss 1, Pp 31-41 (2021)
Background: This study investigated the inhibition of tumor growth in castrate-resistant prostate cancer (CRPC)-bearing mice by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)-overexpressing adipose-derived stem cells (ADSCs) (hTERT
Externí odkaz:
https://doaj.org/article/77d8b066ce1d49aabeb60076435b6886
Publikováno v:
Prostate International
Prostate International, Vol 9, Iss 1, Pp 31-41 (2021)
Prostate International, Vol 9, Iss 1, Pp 31-41 (2021)
Background: This study investigated the inhibition of tumor growth in castrate-resistant prostate cancer (CRPC)-bearing mice by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)-overexpressing adipose-derived stem cells (ADSCs) (hTERT
Publikováno v:
Biomolecules & Therapeutics. 28:240-249
Despite the therapeutic effect of mesenchymal stem cells (MSCs) in ischemic diseases, pathophysiological conditions, including hypoxia, limited nutrient availability, and oxidative stress restrict their potential. To address this issue, we investigat
Publikováno v:
International Journal of Medical Sciences
Diabetes-mediated hyperglycemia is a major risk factor for renal fibrosis, resulting in the development of chronic kidney diseases. To address this issue, the effect of melatonin, which has an antioxidative potential, on renal fibrosis in human renal
Publikováno v:
Anticancer research. 40(3)
Background/aim Anti-cancer drug resistance restricts the efficacy of chemotherapy in malignant tumors. Casein kinase 2α (CK2α) is highly expressed in 5-fluorouracil (5FU)-resistant colorectal cancer (CRC) cells. We hypothesized that inhibition of C
Publikováno v:
Biochemical and biophysical research communications. 525(2)
Ischemic injury is a major risk factor for fibrosis. However, the precise mechanisms by which fibrosis is regulated and induced under ischemic oxidative stress conditions are unknown. To address this, we investigated the effect of melatonin on ischem
Publikováno v:
Tissue and Cell. 53:93-103
Mesenchymal stem cells (MSCs) are widely used in transplantation therapy due to their multilineage differentiation potential, abundance, and immuno-modulating ability. However, the risk of allograft rejection limits their application. Here, we propos