Effects of CLIC4 on Fucoxanthinol-Induced Apoptosis in Human Colorectal Cancer Cells.

Autor: Yokoyama, Reo¹, Kojima, Hiroyuki¹, Takai, Rie², Ohta, Tohru², Maeda, Hayato³, Miyashita, Kazuo⁴, Mutoh, Michihiro⁵, Terasaki, Masaru^1,6

Publikováno v: Nutrition & Cancer. 2021, Vol. 73 Issue 5, p889-898. 10p. 1 Color Photograph, 1 Diagram, 3 Charts, 1 Graph.

Requirement of CLIC4 Expression in Human Colorectal Cancer Cells for Sensitivity to Growth Inhibition by Fucoxanthinol

Autor: YOKOYAMA, REO, KUSHIBIKI, AYUMI, YAMADA, SHIORI, KUBOTA, ATSUHITO, KOJIMA, HIROYUKI, OHTA, TOHRU, HAMADA, JUNICHI, MAEDA, HAYATO, MUTOH, MICHIHIRO, TERASAKI, MASARU

Publikováno v: Cancer Genomics Proteomics

Background/Aim: Fucoxanthinol (FxOH), a marine carotenoid, induces apoptosis and anoikis in human colorectal cancer (CRC) DLD-1 cells via the down-regulation of chloride intracellular channel 4 (CLIC4) expression, a key molecule for apoptosis. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cd157abf23bf580c800b6838bf6b3b
https://doi.org/10.21873/cgp.20330

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Requirement of CLIC4 Expression in Human Colorectal Cancer Cells for Sensitivity to Growth Inhibition by Fucoxanthinol.

Autor: Yokoyama R; School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan., Kushibiki A; School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan., Yamada S; School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan., Kubota A; School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan., Kojima H; School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan.; Advanced Research Promotion Center, Health Sciences University of Hokkaido, Hokkaido, Japan., Ohta T; Advanced Research Promotion Center, Health Sciences University of Hokkaido, Hokkaido, Japan., Hamada J; Advanced Research Promotion Center, Health Sciences University of Hokkaido, Hokkaido, Japan.; School of Nursing and Social Services, Health Sciences University of Hokkaido, Hokkaido, Japan., Maeda H; Faculty of Agriculture and Life Science, Hirosaki University, Aomori, Japan., Mutoh M; Department of Molecular-Targeting Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Terasaki M; School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan; terasaki@hoku-iryo-u.ac.jp.; Advanced Research Promotion Center, Health Sciences University of Hokkaido, Hokkaido, Japan.

Publikováno v: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2022 Jul-Aug; Vol. 19 (4), pp. 428-444.