Zobrazeno 1 - 10
of 91
pro vyhledávání: '"YINGLI WU"'
Autor:
Yingying Wang, Youping Zhang, Hao Luo, Wei Wei, Wanting Liu, Weiwei Wang, Yunzhao Wu, Cheng Peng, Yanjie Ji, Jianfang Zhang, Chujiao Zhu, Wenhui Bai, Li Xia, Hu Lei, Hanzhang Xu, Leimiao Yin, Wei Weng, Li Yang, Ligen Liu, Aiwu Zhou, Yueyue Wei, Qi Zhu, Weiliang Zhu, Yongqing Yang, Zhijian Xu, Yingli Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5235-5248 (2024)
Inducing the degradation of KRAS represents a novel strategy to combat cancers with KRAS mutation. In this study, we identify ubiquitin-specific protease 2 (USP2) as a novel deubiquitinating enzyme of KRAS in multiple myeloma (MM). Specifically, we d
Externí odkaz:
https://doaj.org/article/d986029b2c5440409f127305b35e13e2
Autor:
Faqi HE, Jianhui ZHU, Rong QI, Yingli WU, Jiujun MIAO, Longyan JIANG, Dongyan WANG, Xian CHEN
Publikováno v:
Shiyou shiyan dizhi, Vol 46, Iss 5, Pp 927-940 (2024)
Predicting the thickness distribution of different types of continental lithofacies is a fundamental task for selecting and evaluating continental shale oil-rich zones. Research on oil-bearing conditions, reservoir characteristics, and mobility of di
Externí odkaz:
https://doaj.org/article/464c7cabb73640b6a580e4cd60ef0e2b
Autor:
Fang Qiu, Yuntong Li, Lile Zhou, Yingli Wu, Yunzhao Wu, Zhilei Fan, Yingying Wang, Dongjun Qin, Chaoqun Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundOvarian cancer is a highly aggressive malignancy with limited therapeutic options and a poor prognosis. Deubiquitinating enzymes (DUBs) have emerged as critical regulators of protein ubiquitination and proteasomal degradation, influencing v
Externí odkaz:
https://doaj.org/article/20da6831785a49798bbf917f3526af96
Autor:
Xingming Zhang, Lou Geng, Yi Tang, Yingying Wang, Youping Zhang, Chujiao Zhu, Hu Lei, Hanzhang Xu, Qi Zhu, Yingli Wu, Wenli Gu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Aberrant upregulation of the ubiquitin-specific protease 14 (USP14) has been found in some malignant tumors, including oral squamous cell carcinoma (OSCC). In this study, we further demonstrated that aberrantly overexpressed USP14 was also c
Externí odkaz:
https://doaj.org/article/7b27daded76546458e3365984e7fa120
Autor:
Ming Zhao, Jia Liu, Qing Yu, Wenbin Xu, Zilu Zhang, Ze Fu, Mingyuan Jia, Xinyi Zeng, Chengyu Wu, Chenjing Ye, Chao Wu, Yingli Wu, Ruibao Ren, Junmin Li, Kankan Wang, Hua Yan
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/95a169681de0472387c4029b7a46fb16
Autor:
Xinhua Xiao, Peihong Wang, Weina Zhang, Jiayi Wang, Mansi Cai, Hua Jiang, Yingli Wu, Huizhuang Shan
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutation accounts for a large proportion of AML patients and diagnosed with poor prognosis. Although the prognosis of FLT3-ITD AML
Externí odkaz:
https://doaj.org/article/90f6a4dd506143818d2808e14ba4d0ba
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-4 (2022)
Abstract Pyruvate kinase M2 (PKM2) plays an important role in the metabolism and proliferation of leukemia cells. Here, we show that deubiquitinase JOSD2, a novel tumor suppressor, blocks PKM2 nuclear localization by reducing its K433 acetylation in
Externí odkaz:
https://doaj.org/article/457f9b36d83141fa80e00318f326897e
Autor:
Zilu Zhang, Chenjing Ye, Jia Liu, Wenbin Xu, Chao Wu, Qing Yu, Xiaoguang Xu, Xinyi Zeng, Huizi Jin, Yingli Wu, Hua Yan
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 5, Pp 651-668 (2022)
Objective: Multiple myeloma (MM) remains incurable with high rates of relapse. New therapeutic drugs are therefore urgently needed to improve the prognosis. JaponiconeA (JA), a natural product isolated from Inula japonica Thunb, has shown good anti-M
Externí odkaz:
https://doaj.org/article/fd65ac5d30d64b5e976002f439dd681f
Autor:
Chunhua NI, Jianhui ZHU, Guangxiang LIU, Fubin WANG, Huichong JIA, Wei ZHANG, Yingli WU, Jiujun MIAO
Publikováno v:
Shiyou shiyan dizhi, Vol 43, Iss 5, Pp 826-834 (2021)
The Upper Paleozoic strata in the Hangjinqi area of the Ordos Basin are an important field to increase reserves and productions for the North China Oil and Gas Branch, SINOPEC. It is necessary to conduct a re-evaluation of hydrocarbon generation pote
Externí odkaz:
https://doaj.org/article/e08d5c9225b144ce8e4e94f4fed19b37
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Deubiquitinases (DUBs) are enzymes that control the stability, interactions or localization of most cellular proteins by removing their ubiquitin modification. In recent years, some DUBs, such as USP7, USP9X and USP10, have been identified a
Externí odkaz:
https://doaj.org/article/743c0eea5df84a378ae8cf6f9d17cc62