Zobrazeno 1 - 10
of 4 855
pro vyhledávání: '"YING Xin"'
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103438- (2024)
RAS-selective lethal small molecule 3 (RSL3) is a small-molecule compound that triggers ferroptosis by inactivating glutathione peroxidase 4. However, its effect on the radioresistance of glioma cells and the underlying mechanisms remains unclear. In
Externí odkaz:
https://doaj.org/article/29a2821395b948d185628bd746754e15
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and AimsPortal vein tumor thrombus (PVTT) occurs frequently in hepatocellular carcinoma (HCC) patients. However, there is currently no satisfactory treatment. Radiotherapy (RT) and tyrosine kinase inhibitors (TKI) are currently commonly us
Externí odkaz:
https://doaj.org/article/c4f37227028042bb948dc76eec0aaee1
Autor:
Chuchu Liu, Jinlong Wei, Xuanzhong Wang, Qin Zhao, Jincai Lv, Zining Tan, Ying Xin, Xin Jiang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
According to official statistics, cancer remains the main reason of death and over 50% of patients with cancer receive radiotherapy. However, adverse consequences after radiation exposure like radiation-induced skin reactions (RISR) have negative or
Externí odkaz:
https://doaj.org/article/543993b3898047a39024acdff4b7facb
Publikováno v:
Linchuang shenzangbing zazhi, Vol 24, Iss 4, Pp 349-352 (2024)
Externí odkaz:
https://doaj.org/article/44a3b663fbf1456bb7e751b886b22fed
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionAs one of the main grain crops in China, maize is highly susceptible to Aspergillus infection during processing, storage and transportation due to high moisture at harvest, which results in the loss of quality. The aim of this study is to
Externí odkaz:
https://doaj.org/article/9446d5575f5f4395be10e986a498cb2f
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107264- (2024)
Disturbances in copper (Cu) homeostasis have been observed in diabetes and associated complications. Cu is an essential micronutrient that plays important roles in various fundamental biological processes. For example, diabetic cardiomyopathy is asso
Externí odkaz:
https://doaj.org/article/c40b377ad53546dfa13ccd313e7f0b5e
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/909897d1b0244528a6abfdc5950d4a03
Autor:
Cheng Qian, Ying Xin, Cheng Qi, Hui Wang, Bryan C. Dong, Donald J. Zack, Seth Blackshaw, Samer Hattar, Feng-Quan Zhou, Jiang Qian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Previous studies of neuronal survival have primarily focused on identifying intrinsic mechanisms controlling the process. This study explored how intercellular communication contributes to retinal ganglion cell (RGC) survival following optic
Externí odkaz:
https://doaj.org/article/b1cda4bead69404db2565077129f3d56
Autor:
Hengru Guo, Ying Xin, Saifei Wang, Xiaoning Zhang, Yanqi Ren, Bo Qiao, Hongjiang Li, Jing Wu, Xiao Hao, Lijun Xu, Yushan Yan, Haohao Zhang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Imbalance in energy regulation is a major cause of insulin resistance and diabetes. Melanocortin-4 receptor (MC4R) signaling at specific sites in the central nervous system has synergistic but non-overlapping functions. However, t
Externí odkaz:
https://doaj.org/article/7e4310646aaf432fa472192425a584ff
Autor:
Ying Cheng, Chunjiao Wu, Lin Wu, Jun Zhao, Yanqiu Zhao, Lulu Chen, Ying Xin, Liang Zhang, Pinhua Pan, Xingya Li, Juan Li, Xiaorong Dong, Ke Tang, Emei Gao, Fei Yu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This single-arm, multi-center clinical trial aimed to evaluate the safety, tolerability, DLT, recommended dose (RD), preliminary efficacy, and pharmacokinetics (PK) characteristics of lurbinectedin, a selective inhibitor of oncogenic transcr
Externí odkaz:
https://doaj.org/article/aaeda2d4fe5546aaa40b29b0239798e3