S43 Results from the STAR-COVID19 trial, a double-blind RCT of stabilised, synthetic sulforaphane in hospitalised patients with suspected COVID19

Autor: MB Long, H Abo-Leyah, YH Giam, T Vadiveloo, RC Hull, HR Keir, T Pembridge, D Alferes de Lima, BJM New, S Inglis, A Gilmour, C Hughes, L Delgado, G MacLennan, AT Dinkova-Kostova, JD Chalmers

Publikováno v: ‘The fast and the furious’ – Clinical studies in COVID-19.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f139f8d29397de5f542168f2216182dc
https://doi.org/10.1136/thorax-2022-btsabstracts.49

Airway IL-1β is related to disease severity and mucociliary function in bronchiectasis.

Autor: Perea L; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Biomedical Research Institute August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Bottier M; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, National Heart and Lung Institute, Imperial College London, London, UK., Cant E; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Richardson H; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Dicker AJ; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Shuttleworth M; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Giam YH; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Abo-Leyah H; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Finch S; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Huang JT; Division of Systems Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Shteinberg M; Pulmonology Institute and CF Center, Carmel Medical Center, Haifa, Israel., Goeminne PC; AZNikolaas, Sint-Niklaas, Belgium., Polverino E; Vall d'Hebron University Hospital, Barcelona, Spain., Altenburg J; Amsterdam UMC, Amsterdam, The Netherlands., Blasi F; Department of Pathophysiology and Transplantation, Università Degli Studi Di Milano, Milan, Italy.; Department of Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, Milan, Italy., Welte T; Department of Respiratory Medicine, Medizinische Hochschule Hannover, Hannover, Germany., Aliberti S; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; IRCCS Humanitas Research Hospital, Respiratory Unit, Milan, Italy., Sibila O; Respiratory Department, Hospital Clinic, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain., Chalmers JD; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Senior authors contributed equally to this manuscript., Shoemark A; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK a.shoemark@dundee.ac.uk.; Senior authors contributed equally to this manuscript.

Publikováno v: The European respiratory journal [Eur Respir J] 2024 Aug 15; Vol. 64 (2). Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).

A serum calprotectin lateral flow test as an inflammatory and prognostic marker in acute lung infection: a prospective observational study.

Autor: Gilmour A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.; These authors contributed equally., Hughes C; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.; These authors contributed equally., Giam YH; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Hull RC; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.; University of Sheffield, Sheffield, UK., Pembridge T; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Abo-Leyah H; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Thompson AAR; University of Sheffield, Sheffield, UK., Condliffe AM; University of Sheffield, Sheffield, UK., Shoemark A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Chalmers JD; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Long MB; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.

Publikováno v: ERJ open research [ERJ Open Res] 2024 Jun 17; Vol. 10 (3). Date of Electronic Publication: 2024 Jun 17 (Print Publication: 2024).

Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection.

Autor: Long MB; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Indicates equal contribution., Howden AJM; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Indicates equal contribution., Keir HR; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Indicates equal contribution., Rollings CM; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Indicates equal contribution., Giam YH; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Pembridge T; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Delgado L; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Abo-Leyah H; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Lloyd AF; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK., Sollberger G; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Max Planck Institute for Infection Biology, Berlin, Germany., Hull R; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Gilmour A; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Hughes C; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., New BJM; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Cassidy D; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Shoemark A; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Richardson H; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Lamond AI; Division of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK., Cantrell DA; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK., Chalmers JD; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK j.chalmers@dundee.ac.uk.; Indicates joint senior authorship., Brenes AJ; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Division of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK.; Indicates joint senior authorship.

Publikováno v: The European respiratory journal [Eur Respir J] 2024 Mar 07; Vol. 63 (3). Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).

Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial.

Autor: Keir HR; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Long MB; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Abo-Leyah H; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Giam YH; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Vadiveloo T; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Pembridge T; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Hull RC; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Delgado L; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Band M; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., McLaren-Neil F; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Adamson S; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Lahnsteiner E; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Gilmour A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Hughes C; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., New BJ; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Connell D; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Dowey R; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Turton H; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Richardson H; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Cassidy D; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Cooper J; NHS Grampian, Aberdeen, UK., Suntharalingam J; Royal United Hospitals, Bath, UK., Diwakar L; University Hospital North Midlands, Stoke-on-Trent, UK., Russell P; Princess Alexandria Hospital, Harlow, UK., Underwood J; Cardiff & Vale University Health Board, Cardiff, UK., Hicks A; Portsmouth Hospitals NHS Trust, Portsmouth, UK., Dosanjh DP; University Hospitals Birmingham, Birmingham, UK., Sage B; NHS Highland, Inverness, UK., Dhasmana D; NHS Fife, Kirkcaldy, UK., Spears M; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Thompson AR; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Brightling C; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Smith A; NHS Lanarkshire, Wishaw, UK., Patel M; NHS Lanarkshire, Wishaw, UK., George J; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Condliffe AM; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Shoemark A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., MacLennan G; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Chalmers JD; Molecular and Clinical Medicine, University of Dundee, Dundee, UK. Electronic address: jchalmers@dundee.ac.uk.

Publikováno v: The Lancet. Respiratory medicine [Lancet Respir Med] 2022 Dec; Vol. 10 (12), pp. 1119-1128. Date of Electronic Publication: 2022 Sep 05.