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pro vyhledávání: '"YFP, Yellow fluorescent protein"'
Akademický článek
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Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1412-1433 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Anoctamin 1 (ANO1) or TMEM16A gene encodes a member of Ca2+ activated Cl– channels (CaCCs) that are critical for physiological functions, such as epithelial secretion, smooth muscle contraction and sensory signal transduction. The attraction and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b93ad5ed1da50ffcb970b7aa59df7fe
https://doi.org/10.1016/j.apsb.2020.12.003
https://doi.org/10.1016/j.apsb.2020.12.003
Autor:
Gemma Navarro, Alvaro Lladser, Javier Campos, Alexandra Espinoza, Francisco Contreras, Carolina Prado, Iu Raïch, Rodrigo Pacheco, Rafael Franco, Francisco Osorio-Barrios, Ernesto Lopez, Valentina Ugalde
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 489-506 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and aims: CD4+ T cells constitute central players in inflammatory bowel diseases (IBDs), driving inflammation in the gut mucosa. Current evidence indicates that CCR9 and the integrin α4β7 are necessary and sufficient to imprint colonic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17853d8965fd2dd62836241f51298962
http://www.sciencedirect.com/science/article/pii/S2352345X21000771
http://www.sciencedirect.com/science/article/pii/S2352345X21000771
Autor:
Marina Pasca di Magliano, Ben L. Allen, Filip Bednar, Hui-Ju Wen, Yaqing Zhang, Paloma E. Garcia, Howard C. Crawford, Michael K. Scales, Amara Z. Shaikh, Esther Kim, Yara S. El-Tawil, Maeva Adoumie, Deneen M. Wellik
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 581-599 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 581-599 (2020)
Background & Aims Although the healthy pancreas consists mostly of epithelial cells, pancreatic cancer and the precursor lesions known as pancreatic intraepithelial neoplasia, are characterized by an extensive accumulation of fibroinflammatory stroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bb9a4858459dea9c49e9fd7caeb3bb
http://europepmc.org/articles/PMC7399194
http://europepmc.org/articles/PMC7399194
Publikováno v:
The Journal of Biological Chemistry
Reactive oxygen species are key factors that strongly affect the cellular redox state and regulate various physiological and cellular phenomena. To monitor changes in the redox state, we previously developed fluorescent redox sensors named Re-Q, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becef2d680d3fc03b5ca82792cac9340
http://europepmc.org/articles/PMC8487062
http://europepmc.org/articles/PMC8487062
Publikováno v:
The Journal of Biological Chemistry
Transient receptor potential canonical type 5 (TRPC5) ion channels are expressed in the brain and kidney and have been identified as promising therapeutic targets whose selective inhibition can protect against diseases driven by a leaky kidney filter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf825fab8dd647992a21e5c49767acc
http://europepmc.org/articles/PMC8191310
http://europepmc.org/articles/PMC8191310
Autor:
Maja Malnar, Angela Bachi, Helena H. Chowdhury, Anemari Horvat, Patrizia D’Adamo, Antonia Gurgone, Saša Trkov Bobnar, Marko Muhič, Lorenzo Piemonti, Maria Lidia Mignogna, Michela Masetti, Jelena Velebit, Veronica Bianchi, Robert Zorec, Matjaž Stenovec, Alessia Mercalli, Katja Fink, Sara Belloli, Stefano Taverna, Maja Potokar, Marko Kreft, Rosa Maria Moresco, Nina Vardjan, Maddalena Ripamonti, Umberto Restuccia
Publikováno v:
Metabolism
Metabolism, clinical and experimental
116 (2021): 154463. doi:10.1016/j.metabol.2020.154463
info:cnr-pdr/source/autori:D'Adamo P.; Horvat A.; Gurgone A.; Mignogna M.L.; Bianchi V.; Masetti M.; Ripamonti M.; Taverna S.; Velebit J.; Malnar M.; Muhic M.; Fink K.; Bachi A.; Restuccia U.; Belloli S.; Moresco R.M.; Mercalli A.; Piemonti L.; Potokar M.; Bobnar S.T.; Kreft M.; Chowdhury H.H.; Stenovec M.; Vardjan N.; Zorec R./titolo:Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse/doi:10.1016%2Fj.metabol.2020.154463/rivista:Metabolism, clinical and experimental (Print)/anno:2021/pagina_da:154463/pagina_a:/intervallo_pagine:154463/volume:116
Metabolism, clinical and experimental
116 (2021): 154463. doi:10.1016/j.metabol.2020.154463
info:cnr-pdr/source/autori:D'Adamo P.; Horvat A.; Gurgone A.; Mignogna M.L.; Bianchi V.; Masetti M.; Ripamonti M.; Taverna S.; Velebit J.; Malnar M.; Muhic M.; Fink K.; Bachi A.; Restuccia U.; Belloli S.; Moresco R.M.; Mercalli A.; Piemonti L.; Potokar M.; Bobnar S.T.; Kreft M.; Chowdhury H.H.; Stenovec M.; Vardjan N.; Zorec R./titolo:Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse/doi:10.1016%2Fj.metabol.2020.154463/rivista:Metabolism, clinical and experimental (Print)/anno:2021/pagina_da:154463/pagina_a:/intervallo_pagine:154463/volume:116
Objectives GDI1 gene encodes for αGDI, a protein controlling the cycling of small GTPases, reputed to orchestrate vesicle trafficking. Mutations in human GDI1 are responsible for intellectual disability (ID). In mice with ablated Gdi1, a model of ID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b634b090f73e01f5e64f5a419978ac
http://europepmc.org/articles/PMC7871014
http://europepmc.org/articles/PMC7871014
Publikováno v:
The Journal of Biological Chemistry
Ca2+/calmodulin-dependent inactivation (CDI) of CaV channels is a critical regulatory process that tunes the kinetics of Ca2+ entry for different cell types and physiologic responses. CDI is mediated by calmodulin (CaM), which is bound to the IQ doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9b4f8af3eaa905ed80ea2ad9b94d93e
https://pubmed.ncbi.nlm.nih.gov/33667546
https://pubmed.ncbi.nlm.nih.gov/33667546
Autor:
P.A. Shenoy, Michelle L. Halls, Luigi Aurelio, Tim Quach, Joshua W. Conner, Quynh N. Mai, Stephen J. Hill, Thomas P. Davis, Meritxell Canals, Christopher J.H. Porter, Nigel W. Bunnett, Arisbel B. Gondin, Cameron J. Nowell, Holly R. Yeatman, Bim Graham, Nicholas A. Veldhuis, Jeffri S. Retamal, Daniel P. Poole, Stephen J. Briddon
Publikováno v:
The Journal of Biological Chemistry
G-protein-coupled receptors (GPCRs) are traditionally known for signaling at the plasma membrane, but they can also signal from endosomes after internalization to control important pathophysiological processes. In spinal neurons, sustained endosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b62515ab0e736f2319a04571ef82b6
https://pubmed.ncbi.nlm.nih.gov/33515548
https://pubmed.ncbi.nlm.nih.gov/33515548