Zobrazeno 1 - 10
of 651
pro vyhledávání: '"YANGQIU LI"'
Autor:
Chengwu Zeng, Dingrui Nie, Xianfeng Wang, Shuxin Zhong, Xiangbo Zeng, Xin Liu, Kangjie Qiu, Xueting Peng, Wenyi Zhang, Shengting Chen, Xianfeng Zha, Cunte Chen, Zhenhua Chen, Weizhang Wang, Yangqiu Li
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Background In the ongoing battle against BCR-ABL+ leukemia, despite significant advances with tyrosine kinase inhibitors (TKIs), the persistent challenges of drug resistance and the enduring presence of leukemic stem cells (LSCs) remain form
Externí odkaz:
https://doaj.org/article/be29b6a8fe664f229ed1b77ac5e5751c
Autor:
Songnan Sui, Mengjun Zhong, Shuxin Zhong, Xueting Peng, Lipeng Mao, Cunte Chen, Chengwu Zeng, Oscar Junhong Luo, Yangqiu Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Exhaustion is a key factor that influences the efficacy of chimeric antigen receptor T (CAR-T) cells. Our previous study demonstrated that a bromodomain protein 4 (BRD4) inhibitor can revise the phenotype and function of exhausted
Externí odkaz:
https://doaj.org/article/4ffb6b26b2d74680b653b6d87757a4c9
Autor:
Yun Tian, Jiafan Guo, Lipeng Mao, Zhixi Chen, Xingwei Zhang, Yangqiu Li, Yikai Zhang, Xianfeng Zha, Oscar Junhong Luo
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Quiescent self-renewal of leukemia stem cells (LSCs) and resistance to conventional chemotherapy are the main factors leading to relapse of acute myeloid leukemia (AML). Alpha-enolase (ENO1), a key glycolytic enzyme, has been show
Externí odkaz:
https://doaj.org/article/1b76bb0bad774a7c84ce0c6890428e9f
Publikováno v:
Blood Science, Vol 6, Iss 4, p e00204 (2024)
The zinc finger transcription factor B-cell CLL/lymphoma 11B gene (BCL11B, CTIP2) plays a crucial role in T-cell development, but its role in T-cell malignancies has not yet been definitively clarified. In the literature, 2 contradictory hypotheses o
Externí odkaz:
https://doaj.org/article/6accae13d3fa44e8a1df84fe6a05dbce
Autor:
Yang-Si Li, Wen-Pu Lai, Kai Yin, Mei-Mei Zheng, Hai-Yan Tu, Wei-Bang Guo, Liang Li, Shou-Heng Lin, Zhen Wang, Lu Zeng, Ben-Yuan Jiang, Zhi-Hong Chen, Qing Zhou, Xu-Chao Zhang, Jin-Ji Yang, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Yi Pan, Hua-Jun Chen, Fa-Man Xiao, Hao Sun, Yue-Li Sun, Xiao-Yan Bai, E.-E. Ke, Jia-Xin Lin, Si-Yang Maggie Liu, Yangqiu Li, Oscar Junhong Luo, Yi-Long Wu
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114613- (2024)
Summary: Leptomeningeal metastases (LMs) remain a devastating complication of non-small cell lung cancer (NSCLC), particularly following osimertinib resistance. We conducted single-cell RNA sequencing on cerebrospinal fluid (CSF) from EGFR-mutant NSC
Externí odkaz:
https://doaj.org/article/0665f6377f1241e58a85cf57da13bbbc
Autor:
Letong Cai, Wenpu Lai, Danlin Yao, Yinfeng Gu, Chaofeng Liang, Lian Liu, Jing Lai, Zhi Yu, Xianfeng Zha, Xibao Yu, Xiuli Wu, Shaohua Chen, Oscar Junhong Luo, Yangqiu Li, Chunyan Wang, Pengfei Qin, Xin Huang, Ling Xu
Publikováno v:
Blood Science, Vol 6, Iss 3, p e00194 (2024)
Tissue-resident memory T (TRM) cells infiltrating solid tumors could influence tumor progression and the response to immune therapies. However, the proportion and prognostic value of TRM cells in the bone marrow (BM) of patients with acute myeloid le
Externí odkaz:
https://doaj.org/article/d300d769922143ca97253538e7515d90
Autor:
Xibao Yu, Yan Wang, Jiaxiong Tan, Yuchen Li, Pengyue Yang, Xuan Liu, Jing Lai, Yue Zhang, Letong Cai, Yinfeng Gu, Ling Xu, Yangqiu Li
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Venetoclax, an inhibitor that selectively targets B cell lymphoma-2 (BCL-2) that has been approved for treating adult acute myeloid leukemia (AML) in combination with hypomethylating agents. However, its short duration of response and emerge
Externí odkaz:
https://doaj.org/article/1600aa7c8b4d400c9820bcced65bca1b
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-34 (2023)
Abstract In one decade, immunotherapy based on immune checkpoint blockades (ICBs) has become a new pillar of cancer treatment following surgery, radiation, chemotherapy, and targeted therapies. However, not all cancer patients benefit from single or
Externí odkaz:
https://doaj.org/article/2dda069691f6495ea7e51c40cbe19faf
Autor:
Qi Hou, Penglin Wang, Xueting Kong, Junjie Chen, Chao Yao, Xiaodan Luo, Yangqiu Li, Zhenyi Jin, Xiuli Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Introductionγδ T cells recognize and exert cytotoxicity against tumor cells. They are also considered potential immune cells for immunotherapy. Our previous study revealed that the altered expression of immune checkpoint T-cell immunoreceptor with
Externí odkaz:
https://doaj.org/article/96913cda997b438b8770e2ca9a415aa0
Autor:
Xibao Yu, Yuchen Li, Pengyue Yang, Yan Wang, Xuan Liu, Letong Cai, Jing Lai, Yue Zhang, Xianfeng Zha, Grzegorz Krzysztof Przybylski, Ling Xu, Yangqiu Li
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/2bd41c855cc74585bd5067a0b9c4393b