Zobrazeno 1 - 10
of 15
pro vyhledávání: '"YAN-JYU TSAI"'
Publikováno v:
Journal of Food and Drug Analysis. 19
Baicalein induces the formation of superoxide and hydroxyl radicals via 12-lipoxygenasc (12-LOX) in the B16F10 mouse melanoma cell line; baicalein also causes a reduction in cellular viability and induces cell apoptosis. In this study, we utilized RO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48878bf7a4760ddc56d05b70e8a639a0
https://doi.org/10.38212/2224-6614.2211
https://doi.org/10.38212/2224-6614.2211
Autor:
Chuang Ye Hong, Ming Hsien Chien, Tzu Ting Chen, Chung Chi Yu, Chien-Huang Lin, Yan Jyu Tsai, Chih Ming Weng, Wan Hsuan Tung, Bing Chang Chen, Ming Chih Yu, Kua Jen Bai
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833:2823-2833
Connective tissue growth factor (CTGF) plays an important role in lung fibrosis. In this study, we investigated the role of Rac1, mixed-lineage kinase 3 (MLK3), c-Jun N-terminal kinase (JNK), and activator protein-1 (AP-1) in CTGF-induced collagen I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93acd84d4d15799715df0ddb89e88edb
https://doi.org/10.1016/j.bbamcr.2013.07.016
https://doi.org/10.1016/j.bbamcr.2013.07.016
Publikováno v:
Journal of Experimental & Clinical Medicine. 3:126-131
Background Coumarin is a well-known plant-derived natural product, which is extensively used as a biologically active compound. Coumarins that possess hydroxyl groups in their benzenoid ring were shown to have potent antioxidant and radical-scavengin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad931755f80b46dfc1fdf7ff30054607
https://doi.org/10.1016/j.jecm.2011.04.006
https://doi.org/10.1016/j.jecm.2011.04.006
Publikováno v:
Free Radical Biology and Medicine. 46:1197-1203
In a previous study, we demonstrated that baicalein induces hydroxyl radical formation in human platelets but the mechanisms are unclear. Herein, we show, using an electron spin resonance technique, that baicalein also induces hydroxyl radical format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73311cd96fb410ce65266d6df07c7d46
https://doi.org/10.1016/j.freeradbiomed.2009.01.024
https://doi.org/10.1016/j.freeradbiomed.2009.01.024
Publikováno v:
Free Radical Biology and Medicine. 39:237-248
Several free radical intermediates formed during synthesis of prostaglandin H synthase (PGHS) catalyze the biosynthesis of prostaglandins from arachidonic acid (AA). We attempted to directly detect free radical intermediates of PGHS in cells. Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a346400f8a4e22062ea8bd92683d3659
https://doi.org/10.1016/j.freeradbiomed.2005.03.011
https://doi.org/10.1016/j.freeradbiomed.2005.03.011
Autor:
Hideaki Abe, Tsutomu Hatano, Sei-ichi Tanuma, Nishimura Koji, Hiroshi Sakagami, Takuo Okuda, Yan Jyu Tsai, Hideharu Maruta, Takashi Yoshida, Kazuma Aoki, Fumiaki Uchiumi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1158:251-256
The inhibitory effects on poly(ADP-ribose) glycohydrolase purified from human placenta of three classes of chemically defined tannins; gallotannins, ellagitannins and condensed tannins, were examined in vitro. Oligomeric ellagitannins were found to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0da621b05785b3b68db45f6dcf3c7a
https://doi.org/10.1016/0304-4165(93)90022-z
https://doi.org/10.1016/0304-4165(93)90022-z
Publikováno v:
The American Journal of Chinese Medicine. 21:45-50
The protective activity against carbon tetrachloride induced hepatotoxicity of several phenolic flavan-3-ols and their derivatives has been assessed. Our research showed that monomers possessing a pyrogallol moiety as the B-ring had greater activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8c994ae2460e02cfb42579a9feb9a8
https://doi.org/10.1142/s0192415x93000066
https://doi.org/10.1142/s0192415x93000066
Autor:
T. Aoki, Tsutomu Hatano, Sei-ichi Tanuma, Yan-Jyu Tsai, Hideharu Maruta, Hideaki Abe, Hiroshi Sakagami, T. Okuda
Publikováno v:
Journal of Biological Chemistry. 267:14436-14442
Oligomeric ellagitannins (nobotanins B, E, and K) were found to be potent inhibitors of poly(ADP-ribose) glycohydrolase purified from mouse mammary tumor 34I cells. Kinetic analysis revealed that the inhibition of nobotanin B (dimer) was competitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc84b32868d13d9f5f4684dea7c1fd9
https://doi.org/10.1016/s0021-9258(19)49731-7
https://doi.org/10.1016/s0021-9258(19)49731-7
Autor:
George Hsiao, Yan Jyu Tsai, Joen Rong Sheu, Cheng Ying Hsieh, Tzeng-Fu Chen, Jie Jen Lee, Duen Suey Chou
Publikováno v:
Journal of agricultural and food chemistry. 55(3)
The pro-oxidant activities of baicalein, morin, myricetin, quercetin, and rutin were examined in various cell-containing systems including human platelets, rat vascular smooth muscle cells, human umbilical vein endothelial cells (HUVECs), human THP-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f082845bad68c47ec61748b389ee2abb
https://pubmed.ncbi.nlm.nih.gov/17263456
https://pubmed.ncbi.nlm.nih.gov/17263456
Autor:
Tzeng-Fu Chen, Duen Suey Chou, Ming Yi Shen, George Hsiao, Joen Rong Sheu, Chih Hsiang Chan, Yan Jyu Tsai
Publikováno v:
Journal of biomedical science. 13(3)
The intracellular mechanisms underlying oxidized low-density lipoprotein (oxLDL)-signaling pathways in platelets are not yet completely understood. Therefore, the aim of this study was to further examine the effects of oxLDL in prevention of platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc2366eecf2e3fb78c2528b7b68d53c
https://pubmed.ncbi.nlm.nih.gov/16283430
https://pubmed.ncbi.nlm.nih.gov/16283430