Zobrazeno 1 - 10
of 7 760
pro vyhledávání: '"YAN HAN"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Congenital long QT syndrome (LQTS) is a genetic heart disorder, which may lead to life-threatening arrhythmias, especially in children. Here, we reported two children who were initially misdiagnosed with epilepsy and experienced Torsades de
Externí odkaz:
https://doaj.org/article/27572d58c7b74a3183274a04ba09281d
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The otopetrin (OTOP) proteins were recently characterized as extracellular proton-activated proton channels. Several recent OTOP channel structures demonstrated that the channels form a dimer with each subunit adopting a double-barrel archit
Externí odkaz:
https://doaj.org/article/fee8b1b0a20045809bc5c4255dda1df3
Autor:
Yan Han, Zehua Shao, Yuanhao Zhang, Huan Zhao, Zirui Sun, Chaokuan Yang, Hao Tang, Yu Han, Chuanyu Gao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study investigates how dynamic fluctuations in matrix stiffness affect the behavior of cardiac fibroblasts (CFs) within a three-dimensional (3D) hydrogel environment. Using hybrid hydrogels with tunable stiffness, we created an in vitro
Externí odkaz:
https://doaj.org/article/cfca4ea9b61a44578d109b58e84df563
Autor:
Julei Zhang, Zeliang He, Chenlu Xiong, Yuanyuan Yao, Chengliang Zhang, Wende Yao, Sihan Yang, Xiaodong Li, Yan Han
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Excessive scar formation such as hypertrophic scars and keloids, resulting from trauma or surgical procedures, present a widespread concern for causing disfigurement, discomfort, and functional limitations. Macrophages play pivotal roles in
Externí odkaz:
https://doaj.org/article/02d7d91653e2485284f0c9141dcd3865
Publikováno v:
eLife, Vol 13 (2024)
Transient Receptor Potential Mucolipin 1 (TRPML1) is a lysosomal cation channel whose loss-of-function mutations directly cause the lysosomal storage disorder mucolipidosis type IV (MLIV). TRPML1 can be allosterically regulated by various ligands inc
Externí odkaz:
https://doaj.org/article/d65ce6249e3c458ea37dd79d6cc5c682
Autor:
Mengyuan Chen, Shu-an Wang, Jiayao Yang, Jiawang Bai, Jingyue Gu, Haolong Luo, Xudong Zhang, Yan Han, Jihong Shao, Yan Xu, Shuyan Guo, Xiangmei Ren
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/d92cf929d8004e3886f3f4b506471bb2
Publikováno v:
Frontiers in Nanotechnology, Vol 6 (2024)
ObjectiveNanotechnology offers many advantages in various fields of cancer therapy. This study describes a new method of self-forming nanoparticles (self-nano) using ferric chloride (FeCl₃) and hydrogen peroxide (H2O2) to form the self-nanoparticle
Externí odkaz:
https://doaj.org/article/360e6baf9300447aa67bab12343aa1bd
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Introduction This study aimed to analyze the risk factors associated with isoniazid-resistant and rifampicin-susceptible tuberculosis (Hr-TB) in adults. Method The clinical data of 1,844 adult inpatients diagnosed with culture-positive pulmo
Externí odkaz:
https://doaj.org/article/f4dbc1a93e59499697f1acdbc6e58a0f
Publikováno v:
Journal of Rock Mechanics and Geotechnical Engineering, Vol 16, Iss 5, Pp 1883-1895 (2024)
For engineering structures with saline soil as a filling material, such as channel slope, road subgrade, etc., the rich soluble salt in the soil is an important potential factor affecting their safety performance. This study examines the Atterberg li
Externí odkaz:
https://doaj.org/article/47f8da1dbfaf4a4bb8d6e81c50a3a59c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Product assembly involves extensive production data that is characterized by high dimensionality, multiple samples, and data imbalance. The article proposes an edge computing-based framework for monitoring product assembly quality in industr
Externí odkaz:
https://doaj.org/article/6f8ef98bd33f41ba86854dea126225d5