Zobrazeno 1 - 10 of 10 pro vyhledávání: '"YAKAI SONG"'
1
Akademický článek
A dual-stator brushless doubly-fed generator for wind power application
Autor: Hao Liu, Yakai Song, Chunlan Bai, Guofeng He, Xiaoju Yin
Publikováno v: Archives of Electrical Engineering, Vol vol. 72, Iss No 4, Pp 1073-1087 (2023)
A novelty dual-stator brushless doubly-fed generator (DSBDFG) with magneticbarrier rotor structure is put forward for application in wind power. Compared with a doublyfed induction generator, the DSBDFG has virtues of high reliability and low mainten
Externí odkaz: https://doaj.org/article/e45c36bd895f47758ada8eabe118d4fa
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2
Akademický článek
One-step synthesis of site-specific antibody–drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates
Autor: Wei Shi, Wanzhen Li, Jianxin Zhang, Tiehai Li, Yakai Song, Yue Zeng, Qian Dong, Zeng Lin, Likun Gong, Shuquan Fan, Feng Tang, Wei Huang
Publikováno v: Acta Pharmaceutica Sinica B, Vol 12, Iss 5, Pp 2417-2428 (2022)
Glycosite-specific antibody‒drug conjugatess (gsADCs), harnessing Asn297 N-glycan of IgG Fc as the conjugation site for drug payloads, usually require multi-step glycoengineering with two or more enzymes, which limits the substrate diversification
Externí odkaz: https://doaj.org/article/283a6fa77faa40b79c111a30c6287d90
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6
A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies
Autor: Xiaojie Deng, Feng Tang, Yakai Song, Likun Gong, Wei Huang, Wei Shi, Qiuping Qin
Publikováno v: Journal of Immunological Methods. 499:113180
We aimed to develop a homogeneous time-resolved fluorometric energy transfer assay for assessment of human neonatal Fc receptor binding activity with IgG-type antibodies. The assay was configured with FcRn-coupled with Eu cryptate via biotin and stre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b3e1db6d8a1acdeba3e52d631ad6da
https://doi.org/10.1016/j.jim.2021.113180
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7
Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOT1L) Inhibitors using a Target-Specific Scoring Function for the (S)-Adenosyl-l-methionine (SAM)-Dependent Methyltransferase Family
Autor: Linjuan Li, Bidong Zhang, Wei Wan, Yulan Wang, Mingyue Zheng, Hualiang Jiang, Jing Xing, Shijie Chen, Hao Jiang, Cheng Luo, Yakai Song
Publikováno v: Journal of Medicinal Chemistry. 60:2026-2036
The disruptor of telomeric silencing 1-like (DOT1L) protein is a histone H3K79 methyltransferase that plays a key role in transcriptional elongation and cell cycle regulation and is required for the development and maintenance of MLL-rearranged mixed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6dedd2548aa76e7838523469dbea1b
https://doi.org/10.1021/acs.jmedchem.6b01785
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8
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay
Autor: Yuanyuan Zhang, Fulin Lian, Naixia Zhang, Linjuan Li, Jingqiu Liu, Hong Ding, Hualiang Jiang, Yu-Chih Liu, Chenhua Zhang, Shijie Chen, Senhao Xiao, Yantao Chen, Kaixian Chen, Yakai Song, Cheng Luo
Publikováno v: Bioorganicmedicinal chemistry. 26(8)
DOT1L (the disruptor of telomeric silencing 1-like), through its methyltransferase activity of H3K79, plays essential roles in transcriptional regulation, cell cycle regulation, and DNA damage response. In addition, DOT1L is believed to be involved i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be5c263e061992d01e36d0b360ad8bf
https://pubmed.ncbi.nlm.nih.gov/29534934
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9
Akademický článek
SEDIMENTARY FACIES AND EVOLUTION OF HUAGANG FORMATION IN XIHU DEPRESSION, EAST CHINA SEA SHELF BASIN.
Autor: Xinyu Hou1, Changmin Zhang1 317894250@qq.com, Taiju Yin1, Guowei Hou2, Junjie Li2, Yakai Song1, Jifeng Xu1
Publikováno v: Fresenius Environmental Bulletin. Nov2020, Vol. 29 Issue 11, p9751-9762. 12p.
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