Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Y.E. Rahman"'
Publikováno v:
Biochemical and Biophysical Research Communications. 116:368-374
The phospholipid-nucleoside conjugates 1-beta-D-arabinofuranosylcytosine-5'-diphosphate-L-1,2-dipalmitin (1), -distearin (2), and -diolein (3) have been shown to interact rapidly with canine high density lipoprotein and with both high density and low
Autor:
Sandra L. Tollaksen, Elizabeth A. Cerny, Sharron L. Nance, Y.E. Rahman, B.J. Wright, John F. Thomson
Publikováno v:
Experimental Biology and Medicine. 146:1173-1176
SummaryActinomycin D, when encapsulated within liposomes, is less toxic to mice than the nonencapsulated form. A single dose (0.75 mg/kg) or multiple doses (1 × 0.50, 4 × 0.25 mg/kg) significantly increased the mean survival time of mice inoculated
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 401:336-348
Liposomes containing ethylenediaminetetraacetic acid (EDTA) were prepared with different surface properties by varying the liposomal lipid constituents. Positively charged liposomes were prepared with a mixture of phosphatidylcholine, cholesterol, an
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 772:93-101
The effect of the positive surface charge of unilamellar liposomes on the kinetics of their interaction with rat peritoneal macrophages was investigated using three sizes of liposomes: small unilamellar vesicles (approx. 25 nm diameter), prepared by
Publikováno v:
Life Sciences. 31:2061-2071
Using liposomes differing in size and lipid composition, we have studied the uptake characteristics of the liver parenchymal and Kupffer cells. Desferal labeled with iron-59 was chosen as a radiomarker for the liposomal content, because Desferal in i
Autor:
Y.E. Rahman, E.A. Cerny
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 178:61-67
In adult rat liver, by the use of sucrose gradient centrifugation, the intracellular distribution pattern of acid ribonuclease was found to be different from that of acid phosphatase. This finding further confirms our previous results obtained by zon
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 146:484-492
Results obtained by zonal gradient centrifugations demonstrated that rat liver lysosomes are heterogeneous in terms of their enzyme contents. It is suggested that acid phosphatase and cathepsin C on one hand, and acid ribonuclease and cathepsin D on
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 178:68-73
A relationship was found between the activity of three ribonucleases and liver growth. All three liver ribonucleases showed high activity in fetuses 3 days before birth, in new-borns and in suckling rats; these enzyme activities decreased gradually a
Autor:
Y.E. Rahman
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 119:470-479
A third ribonuclease has been found in rat-liver particulates. The properties of this enzyme differ from those of the two other liver ribonucleases previously known: 1. (1) it has a pH optimum between 9.0 and 9.5; 2. (2) there is no natural inhibitor
Publikováno v:
Biochemical and Biophysical Research Communications. 38:670-677
A phospholipase a with optimal activity at pH 7.0–8.0 was found in the membranes of rat liver lysosomes. This enzyme is activated by Ca ++ , and is specific for the fatty acid at the 2-position. The presence of this enzyme in lysosomes is not due t