Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Y.-D. Ida Chen"'
Autor:
Soonil Kwon, Mark O. Goodarzi, Kent D. Taylor, Jinrui Cui, Y.-D. Ida Chen, Jerome I. Rotter, Willa Hsueh, Xiuqing Guo
Publikováno v:
Journal of Probability and Statistics, Vol 2012 (2012)
We developed a multinomial ordinal probit model with singular value decomposition for testing a large number of single nucleotide polymorphisms (SNPs) simultaneously for association with multidisease status when sample size is much smaller than the n
Externí odkaz:
https://doaj.org/article/f5ae768450544349ab7c1dd9e54acf55
Akademický článek
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Autor:
Adam A. Szpiro, Jerome I. Rotter, Kari E. North, Bertha Hidalgo, M. Larissa Avilés-Santa, George J. Papanicolaou, Qibin Qi, Neil Schneiderman, Adrienne M. Stilp, Donna K. Arnett, Jianwen Cai, Bing Yu, Cathy C. Laurie, Robert C. Kaplan, Eric Boerwinkle, Tamar Sofer, Y.-D. Ida Chen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific reports, vol 9, iss 1
Five sequence variants in SLC16A11 (rs117767867, rs13342692, rs13342232, rs75418188, and rs75493593), which occur in two non-reference haplotypes, were recently shown to be associated with diabetes in Mexicans from the SIGMA consortium. We aimed to d
Autor:
Maggie C Y Ng, Daniel Shriner, Brian H Chen, Jiang Li, Wei-Min Chen, Xiuqing Guo, Jiankang Liu, Suzette J Bielinski, Lisa R Yanek, Michael A Nalls, Mary E Comeau, Laura J Rasmussen-Torvik, Richard A Jensen, Daniel S Evans, Yan V Sun, Ping An, Sanjay R Patel, Yingchang Lu, Jirong Long, Loren L Armstrong, Lynne Wagenknecht, Lingyao Yang, Beverly M Snively, Nicholette D Palmer, Poorva Mudgal, Carl D Langefeld, Keith L Keene, Barry I Freedman, Josyf C Mychaleckyj, Uma Nayak, Leslie J Raffel, Mark O Goodarzi, Y-D Ida Chen, Herman A Taylor, Adolfo Correa, Mario Sims, David Couper, James S Pankow, Eric Boerwinkle, Adebowale Adeyemo, Ayo Doumatey, Guanjie Chen, Rasika A Mathias, Dhananjay Vaidya, Andrew B Singleton, Alan B Zonderman, Robert P Igo, John R Sedor, FIND Consortium, Edmond K Kabagambe, David S Siscovick, Barbara McKnight, Kenneth Rice, Yongmei Liu, Wen-Chi Hsueh, Wei Zhao, Lawrence F Bielak, Aldi Kraja, Michael A Province, Erwin P Bottinger, Omri Gottesman, Qiuyin Cai, Wei Zheng, William J Blot, William L Lowe, Jennifer A Pacheco, Dana C Crawford, eMERGE Consortium, DIAGRAM Consortium, Elin Grundberg, MuTHER Consortium, Stephen S Rich, M Geoffrey Hayes, Xiao-Ou Shu, Ruth J F Loos, Ingrid B Borecki, Patricia A Peyser, Steven R Cummings, Bruce M Psaty, Myriam Fornage, Sudha K Iyengar, Michele K Evans, Diane M Becker, W H Linda Kao, James G Wilson, Jerome I Rotter, Michèle M Sale, Simin Liu, Charles N Rotimi, Donald W Bowden, MEta-analysis of type 2 DIabetes in African Americans Consortium
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004517 (2014)
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studi
Externí odkaz:
https://doaj.org/article/56bb7be103094e20a1ebafe269f259c2
Autor:
Pierrick, Wainschtein, Deepti, Jain, Zhili, Zheng, L Adrienne, Cupples, Aladdin H, Shadyab, Barbara, McKnight, Benjamin M, Shoemaker, Braxton D, Mitchell, Bruce M, Psaty, Charles, Kooperberg, Ching-Ti, Liu, Christine M, Albert, Dan, Roden, Daniel I, Chasman, Dawood, Darbar, Donald M, Lloyd-Jones, Donna K, Arnett, Elizabeth A, Regan, Eric, Boerwinkle, Jerome I, Rotter, Jeffrey R, O'Connell, Lisa R, Yanek, Mariza, de Andrade, Matthew A, Allison, Merry-Lynn N, McDonald, Mina K, Chung, Myriam, Fornage, Nathalie, Chami, Nicholas L, Smith, Patrick T, Ellinor, Ramachandran S, Vasan, Rasika A, Mathias, Ruth J F, Loos, Stephen S, Rich, Steven A, Lubitz, Susan R, Heckbert, Susan, Redline, Xiuqing, Guo, Y -D Ida, Chen, Cecelia A, Laurie, Ryan D, Hernandez, Stephen T, McGarvey, Michael E, Goddard, Cathy C, Laurie, Kari E, North, Leslie A, Lange, Bruce S, Weir, Loic, Yengo, Jian, Yang, Michael, Zody
Publikováno v:
Nature genetics. 54(3)
Analyses of data from genome-wide association studies on unrelated individuals have shown that, for human traits and diseases, approximately one-third to two-thirds of heritability is captured by common SNPs. However, it is not known whether the rema
Autor:
Caroline S Fox, Charles C White, Kurt Lohman, Nancy Heard-Costa, Paul Cohen, Yingying Zhang, Andrew D Johnson, Valur Emilsson, Ching-Ti Liu, Y-D Ida Chen, Kent D Taylor, Matthew Allison, Matthew Budoff, CARDIoGRAM Consortium, Jerome I Rotter, J Jeffrey Carr, Udo Hoffmann, Jingzhong Ding, L Adrienne Cupples, Yongmei Liu
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002705 (2012)
Pericardial fat is a localized fat depot associated with coronary artery calcium and myocardial infarction. We hypothesized that genetic loci would be associated with pericardial fat independent of other body fat depots. Pericardial fat was quantifie
Externí odkaz:
https://doaj.org/article/7a6ca7dde06b48ed8d3b76697643b5ff
Akademický článek
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Autor:
Stephen S. Rich, Xiuqing Guo, Bruce M. Psaty, Mina K. Chung, Aladdin H. Shadyab, Nicholas L. Smith, Dan M. Roden, Christine M. Albert, Braxton D. Mitchell, Y.-D. Ida Chen, Matthew A. Allison, Loic Yengo, Barbara McKnight, Jerome I. Rotter, Leslie A. Lange, Mariza de Andrade, Patrick T. Ellinor, Charles Kooperberg, Cathy C. Laurie, Merry-Lynn McDonald, Ramachandran S. Vasan, Ryan D. Hernandez, Kari E. North, Peter M. Visscher, Pierrick Wainschtein, Rasika A. Mathias, Zhili Zheng, Bruce S. Weir, L. Adrienne Cupples, Lisa R. Yanek, Donna K. Arnett, Stephen T. McGarvey, Elizabeth A. Regan, Jian Yang, Ching-Ti Liu, Dawood Darbar, Eric Boerwinkle, Deepti Jain, Susan R. Heckbert, Susan Redline, Benjamin Shoemaker
Heritability, the proportion of phenotypic variance explained by genetic factors, can be estimated from pedigree data 1, but such estimates are uninformative with respect to the underlying genetic architecture. Analyses of data from genome-wide assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fded6a3ee908ece1c1ba106081066cbf
https://doi.org/10.1101/588020
https://doi.org/10.1101/588020