Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Y. Zea-Ponce"'
Publikováno v:
Synapse (New York, N.Y.). 35(1)
Quantitation of the PET benzodiazepine receptor antagonist, [(11)C]Iomazenil, using low specific activity radioligand was recently described. The purpose of this study was to quantitate benzodiazepine receptor binding in human subjects using PET and
Autor:
A, Abi-Dargham, N, Simpson, L, Kegeles, R, Parsey, D R, Hwang, S, Anjilvel, Y, Zea-Ponce, I, Lombardo, R, Van Heertum, J J, Mann, C, Foged, C, Halldin, M, Laruelle
Publikováno v:
Synapse (New York, N.Y.). 32(2)
NNC 756 ((+)-8-chloro-5-(2,3-dihydrobenzofuran-7-yl)-7-hydroxy-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine) is a new high affinity dopamine (DA) D1 receptor antagonist. Labeled with C-11, it has been used as a PET radiotracer to visualize D1 recept
Stability of [123I]IBZM SPECT measurement of amphetamine-induced striatal dopamine release in humans
Autor:
L S, Kegeles, Y, Zea-Ponce, A, Abi-Dargham, J, Rodenhiser, T, Wang, R, Weiss, R L, Van Heertum, J J, Mann, M, Laruelle
Publikováno v:
Synapse (New York, N.Y.). 31(4)
Binding competition between endogenous dopamine (DA) and the D2 receptor radiotracer [123I]IBZM allows measurement of the change in synaptic DA following amphetamine challenge with SPECT in the living human brain. Previous investigations using this t
Autor:
J P, Seibyl, K, Marek, K, Sheff, R M, Baldwin, S, Zoghbi, Y, Zea-Ponce, D S, Charney, C H, van Dyck, P B, Hoffer, R B, Innis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(9)
Iodine-123-beta-CIT has been used as a probe of dopamine transporters in Parkinson's disease patients using SPECT. We studied the test/retest reproducibility of SPECT measures in Parkinson's disease patients and healthy controls obtained after inject
Autor:
M, Laruelle, R N, Iyer, M S, al-Tikriti, Y, Zea-Ponce, R, Malison, S S, Zoghbi, R M, Baldwin, H F, Kung, D S, Charney, P B, Hoffer, R B, Innis, C W, Bradberry
Publikováno v:
Synapse (New York, N.Y.). 25(1)
The competition between endogenous transmitters and radiolabeled ligands for in vivo binding to neuroreceptors might provide a method to measure endogenous transmitter release in the living human brain with noninvasive techniques such as positron emi
Autor:
J P, Seibyl, Y, Zea-Ponce, L, Brenner, R M, Baldwin, J H, Krystal, S J, Offord, S, Mochoviak, D S, Charney, P B, Hoffer, R B, Innis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 37(1)
PET has shown that dose-dependent in vivo occupancy of dopamine receptors by antipsychotic drugs is associated with clinical response to antipsychotic agents and the production of extrapyramidal side effects. We studied the feasibility of administeri
Autor:
M, Laruelle, A, Abi-Dargham, C H, van Dyck, W, Rosenblatt, Y, Zea-Ponce, S S, Zoghbi, R M, Baldwin, D S, Charney, P B, Hoffer, H F, Kung
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 36(7)
This study assesses the feasibility of using SPECT to image intrasynaptic dopamine release in human striatum following dextroamphetamine sulfate (d-amphetamine) challenge testing.A bolus plus constant infusion administration schedule of the D2 recept
Autor:
C H, van Dyck, J P, Seibyl, R T, Malison, M, Laruelle, E, Wallace, S S, Zoghbi, Y, Zea-Ponce, R M, Baldwin, D S, Charney, P B, Hoffer
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 36(7)
The effect of age on human striatal dopamine (DA) transporters was investigated with SPECT using the ligand [123I]2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane ([123I]beta-CIT).Iodine-123-beta-CIT binding in the striatum was examined in 28 healthy
Autor:
A, Abi-Dargham, M, Gandelman, S S, Zoghbi, M, Laruelle, R M, Baldwin, P, Randall, Y, Zea-Ponce, D S, Charney, P B, Hoffer, R B, Innis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 36(2)
Iodine-123-iomazenil is a SPECT radiotracer used to image and quantify benzodiazepine receptors. The reproducibility of the measurement of benzodiazepine receptors in human brain with [123I]iomazenil and SPECT was investigated with a test/retest para
Autor:
M, Laruelle, C, van Dyck, A, Abi-Dargham, Y, Zea-Ponce, S S, Zoghbi, D S, Charney, R M, Baldwin, P B, Hoffer, H F, Kung, R B, Innis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 35(5)
Iodine-123-labeled iodobenzofuran ([123I]IBF) is a potent dopamine D2 antagonist that provides good visualization of D2 receptors in primates.The feasibility of measuring dopamine D2 binding potential with [123I]IBF in humans was evaluated in eight h