Výsledky vyhledávání

Chemoradiotherapy efficacy is predicted by intra-tumour CD8+/FoxP3+ double positive T cell density in locally advanced N2 non-small-cell lung carcinoma

Autor: Véronique Duchatelle, Diane Damotte, Y. Velut, R. Herbst, Ludovic Fournel, G. Boulle, Scott A. Hammond, M. Wislez, Isabelle Cremer, Laure Gibault, Philippe Giraud, Hélène Blons, Marco Alifano, Audrey Mansuet-Lupo, A. Boni, Jean Trédaniel

Publikováno v: European Journal of Cancer
European Journal of Cancer, Elsevier, 2020, 135, pp.221-229. ⟨10.1016/j.ejca.2020.04.040⟩
European Journal of Cancer, 2020, 135, pp.221-229. ⟨10.1016/j.ejca.2020.04.040⟩

Background Radiotherapy is a standard of care for locally advanced stage III N2 non–small-cell lung carcinoma (NSCLC) combined with surgery/chemotherapy. Radiotherapy is hypothesised to induce tumour immunogenic cell death, to release neoantigen re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e180506c23b80a03a68a99ec0102aab4
https://pubmed.ncbi.nlm.nih.gov/32610210

Zobrazit plný text záznamu

Biomarqueurs prédictifs de l’immunothérapie anti-PD1/PD-L1 dans le cancer broncho-pulmonaire non à petites cellules

Autor: François Goldwasser, Diane Damotte, G. Boulle, M. Wislez, Karen Leroy, Y. Velut, Marco Alifano, Isabelle Cremer, Jérôme Biton, Audrey Lupo

Publikováno v: Revue de Pneumologie Clinique. 74:339-350

Immune checkpoint inhibitors (ICI), targeting the PD1/PD-L1 axis has shown their efficacy in lung cancer but only in a restricted population of patients, thus it is mandatory to identify biomarkers predicting the clinical benefit. In this article we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c6df5db82140ff44a77929ec6611ce6
https://doi.org/10.1016/j.pneumo.2018.09.010

Zobrazit plný text záznamu

Analyse du microenvironnement immunitaire par immunohistochimie multiplex dans le cancer bronchopulmonaire non à petites cellules localement évolué : principes et perspectives

Autor: Diane Damotte, Marco Alifano, G. Boulle, P. Giraud, A. Boni, Y. Velut, Audrey Lupo, J. Trédaniel

Publikováno v: Cancer/Radiothérapie. 22:688-693

Recent therapeutic advances in non-small cell lung cancer allow a better understanding of the interactions between the tumour and its direct immune environment. The identification of new immune biomarkers integrating both cell subpopulations and thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3d7ea7f3050bd9e9cfb84e44ce0e505
https://doi.org/10.1016/j.canrad.2018.07.031

Zobrazit plný text záznamu

Proposal for a Combined Histomolecular Algorithm to Distinguish Multiple Primary Adenocarcinomas from Intrapulmonary Metastasis in Patients with Multiple Lung Tumors

Autor: Marco Alifano, Bastien Rance, Audrey Mansuet-Lupo, Hélène Blons, M. Wislez, Jérôme Biton, Pierre Laurent-Puig, Jean-François Regnard, Ronald Herbst, Y. Velut, Makmoud Zarmaev, Marc Barritault, Aurélie Janet-Vendroux, Isabelle Cremer, Ludovic Fournel, Christine Le Hay, Diane Damotte

Publikováno v: Journal of Thoracic Oncology
Journal of Thoracic Oncology, Lippincott, Williams & Wilkins, 2019, 14, pp.844-856. ⟨10.1016/j.jtho.2019.01.017⟩

Introduction Multiple nodules in the lung are being diagnosed with an increasing frequency thanks to high-quality computed tomography imaging. In patients with lung cancer, this situation represents up to 10% of patients who have an operation. For cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f64f0e5b5077fa6511fbf1b058399b
https://hal.archives-ouvertes.fr/hal-03486393/file/S1556086419300930.pdf

Zobrazit plný text záznamu

Abstract 4304: Radio-chemotherapy efficacy is predicted by intra-tumor CD8+FoxP3+ double positive T cell density in locally advanced non-small cell lung carcinoma

Autor: Philippe Giraud, Diane Damotte, Scott A. Hammond, A. Boni, Y. Velut, M. Wislez, Laure Gibault, Jean Trédaniel, Marco Alifano, Audrey Lupo, Véronique Duchatelle, Isabelle Cremer, Ludovic Fournel, Geoffroy Boulle, Hélène Blons

Publikováno v: Cancer Research. 80:4304-4304

Background: radiotherapy is a standard of care for locally advanced stage III (N2) non-small cell lung cancer (NSCLC) combined with surgery and/or chemotherapy. Radiotherapy is hypothesized to induce intra-tumoral immune infiltration via neoantigen r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8397ef4623310de3b2e9f2ba9b5a47ce
https://doi.org/10.1158/1538-7445.am2020-4304

Zobrazit plný text záznamu

[Biomarkers predictive of PD1/PD-L1 immunotherapy in non-small cell lung cancer]

Autor: A, Lupo, M, Alifano, M, Wislez, G, Boulle, Y, Velut, J, Biton, I, Cremer, F, Goldwasser, K, Leroy, D, Damotte

Publikováno v: Revue de pneumologie clinique. 74(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a10bcf1d38208bcd6ad3ffc7169f60f
https://pubmed.ncbi.nlm.nih.gov/30337201

Zobrazit plný text záznamu

[Analysis of immune microenvironment by multiplex immunohistochemistry in locally advanced non-small cell lung cancer: Principles and perspectives]

Autor: G, Boulle, Y, Velut, A, Boni, A, Lupo, M, Alifano, J, Trédaniel, P, Giraud, D, Damotte

Publikováno v: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 22(6-7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1709067b9c4ab78a801c7ef5ff06d67
https://pubmed.ncbi.nlm.nih.gov/30131267

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání