Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Y. Tony Ip"'
Autor:
Yang Sun, Lu Hu, Zhipeng Tao, Gopala K. Jarugumilli, Hannah Erb, Alka Singh, Qi Li, Jennifer L. Cotton, Patricia Greninger, Regina K. Egan, Y. Tony Ip, Cyril H. Benes, Jianwei Che, Junhao Mao, Xu Wu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Previously, the small molecule inhibitor of transcriptional enhanced associate domain (TEAD) MGH-CP1 has been described in stem cells. Here, the authors demonstrate the utility of MGH-CP1 in cancer therapy and find treatment to increase Akt pathway a
Externí odkaz:
https://doaj.org/article/0a919bab3ce842f1938cd997f841b09b
Autor:
Alicia Shields, Alla Amcheslavsky, Elizabeth Brown, Tom V. Lee, Yingchao Nie, Takahiro Tanji, Y. Tony Ip, Andreas Bergmann
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110817- (2022)
Summary: Drosophila Toll-1 and all mammalian Toll-like receptors regulate innate immunity. However, the functions of the remaining eight Toll-related proteins in Drosophila are not fully understood. Here, we show that Drosophila Toll-9 is necessary a
Externí odkaz:
https://doaj.org/article/6a1fc7ad54e6466c9b1985c50dc6f126
Autor:
Huapeng Li, Qi Li, Kyvan Dang, Shan Ma, Jennifer L. Cotton, Sun Yang, Lihua J. Zhu, April C. Deng, Y. Tony Ip, Randy L. Johnson, Xu Wu, Claudio Punzo, Junhao Mao
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3200-3211.e4 (2019)
Summary: Uveal melanoma (UM), the most common ocular malignancy, is characterized by GNAQ/11 mutations. Hippo/YAP and Ras/mitogen-activated protein kinase (MAPK) emerge as two important signaling pathways downstream of G protein alpha subunits of the
Externí odkaz:
https://doaj.org/article/802444966e0647229f7493ecee80a44f
Autor:
Jiaxin Gong, Niraj K. Nirala, Jiazhang Chen, Fei Wang, Pengyu Gu, Qi Wen, Y. Tony Ip, Yang Xiang
Publikováno v:
Science Advances. 9
Adult stem cells are essential for tissue maintenance and repair. Although genetic pathways for controlling adult stem cells are extensively investigated in various tissues, much less is known about how mechanosensing could regulate adult stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe829ccae450ddbba6ac9cb0f663e99
https://doi.org/10.1126/sciadv.adc9660
https://doi.org/10.1126/sciadv.adc9660
Autor:
Nan Gao, Y. Tony Ip, Lanjing Zhang, Michael P. Verzi, James R. Goldenring, Edward M. Bonder, Ghassan Yehia, Ronaldo P. Ferraris, Bin Gao, Chung S. Yang, Qi Li, Victoria Farrell, Ryotaro Sakamori, Ivor Joseph, Iyshwarya Balasubramanian, Xiao Zhang, Juan Flores, Sheila Bandyopadhyay, Shiyan Yu, Kevin Tong, Sayantani Goswami, Yingchao Nie, Luca D'Agostino
The effects of polarized membrane trafficking in mature epithelial tissue on cell growth and cancer progression have not been fully explored in vivo. A majority of colorectal cancers have reduced and mislocalized Rab11, a small GTPase dedicated to tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6136fae2182ae6c0d16016218ac3a39a
https://doi.org/10.1158/0008-5472.c.6510954
https://doi.org/10.1158/0008-5472.c.6510954
Autor:
Nan Gao, Y. Tony Ip, Lanjing Zhang, Michael P. Verzi, James R. Goldenring, Edward M. Bonder, Ghassan Yehia, Ronaldo P. Ferraris, Bin Gao, Chung S. Yang, Qi Li, Victoria Farrell, Ryotaro Sakamori, Ivor Joseph, Iyshwarya Balasubramanian, Xiao Zhang, Juan Flores, Sheila Bandyopadhyay, Shiyan Yu, Kevin Tong, Sayantani Goswami, Yingchao Nie, Luca D'Agostino
Mice with intestinal epithelium specific deletion of Rab11a develop epithelial hyperplasia and dysplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e7720829c0d3e3d5b0664f57f96e44
https://doi.org/10.1158/0008-5472.22421544.v1
https://doi.org/10.1158/0008-5472.22421544.v1
Autor:
Nan Gao, Y. Tony Ip, Lanjing Zhang, Michael P. Verzi, James R. Goldenring, Edward M. Bonder, Ghassan Yehia, Ronaldo P. Ferraris, Bin Gao, Chung S. Yang, Qi Li, Victoria Farrell, Ryotaro Sakamori, Ivor Joseph, Iyshwarya Balasubramanian, Xiao Zhang, Juan Flores, Sheila Bandyopadhyay, Shiyan Yu, Kevin Tong, Sayantani Goswami, Yingchao Nie, Luca D'Agostino
Induced deletion of Rab11 causes Yap nuclear accumulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ea1207bba451b4942b5efac9816d0c
https://doi.org/10.1158/0008-5472.22421535.v1
https://doi.org/10.1158/0008-5472.22421535.v1
Autor:
Nan Gao, Y. Tony Ip, Lanjing Zhang, Michael P. Verzi, James R. Goldenring, Edward M. Bonder, Ghassan Yehia, Ronaldo P. Ferraris, Bin Gao, Chung S. Yang, Qi Li, Victoria Farrell, Ryotaro Sakamori, Ivor Joseph, Iyshwarya Balasubramanian, Xiao Zhang, Juan Flores, Sheila Bandyopadhyay, Shiyan Yu, Kevin Tong, Sayantani Goswami, Yingchao Nie, Luca D'Agostino
Loss of Rab11a increases intestinal tumorigenic susceptibility to carcinogen and other tumor developing mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d6dbaf2f9f9c10003e618b5d49d6eb
https://doi.org/10.1158/0008-5472.22421541.v1
https://doi.org/10.1158/0008-5472.22421541.v1
Autor:
Nan Gao, Y. Tony Ip, Lanjing Zhang, Michael P. Verzi, James R. Goldenring, Edward M. Bonder, Ghassan Yehia, Ronaldo P. Ferraris, Bin Gao, Chung S. Yang, Qi Li, Victoria Farrell, Ryotaro Sakamori, Ivor Joseph, Iyshwarya Balasubramanian, Xiao Zhang, Juan Flores, Sheila Bandyopadhyay, Shiyan Yu, Kevin Tong, Sayantani Goswami, Yingchao Nie, Luca D'Agostino
Rab11a-deficient intestinal tumors have high levels of Yap expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cefc145bbb0ff7981e43062eec91056
https://doi.org/10.1158/0008-5472.22421532.v1
https://doi.org/10.1158/0008-5472.22421532.v1
Autor:
Nan Gao, Y. Tony Ip, Lanjing Zhang, Michael P. Verzi, James R. Goldenring, Edward M. Bonder, Ghassan Yehia, Ronaldo P. Ferraris, Bin Gao, Chung S. Yang, Qi Li, Victoria Farrell, Ryotaro Sakamori, Ivor Joseph, Iyshwarya Balasubramanian, Xiao Zhang, Juan Flores, Sheila Bandyopadhyay, Shiyan Yu, Kevin Tong, Sayantani Goswami, Yingchao Nie, Luca D'Agostino
Detailed description of the various methods utilized in this manuscript in addition to the methods mentioned in the primary article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a32de0e9447afcc8ed075420fd13718
https://doi.org/10.1158/0008-5472.22421526
https://doi.org/10.1158/0008-5472.22421526