Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Y. Sauve"'
Publikováno v:
Experimental Eye Research. 85:381-392
We have examined how transplantation of an RPE cell line to the subretinal space of RCS rats affects the distribution of synaptic connectivity markers in the outer plexiform layer of the retina. Using markers of pre- and post-synaptic profiles (basso
Autor:
Carole A. Bartlett, Lyn Beazley, Sarah A. Dunlop, Raymond D. Lund, Carolyn E. King, Jennifer Rodger, A.C.E. Symonds, Y. Sauve
Publikováno v:
European Journal of Neuroscience. 25:744-752
During development, gradients of EphA receptors (nasal(low)-temporal(high)) and their ligands ephrin-As (rostral(low)-caudal(high)) are involved in establishing topography between retinal ganglion cells (RGCs) and the superior colliculus (SC). EphA5-
Autor:
Zhenglin Yang, Shomi S. Bhattacharya, Y. Sauve, Anneke I. den Hollander, Frans P.M. Cremers, Goutam Karan, Kang Zhang, Christina Chakarova, Jeanne M. Frederick, Bradley J. Katz, Yu Zhao, Wolfgang Baehr, Bernd Wissinger, Eberhart Zrenner, Joseph R. Casey, Xi Li, Bernardo V. Alvarez, Li Jiang
Publikováno v:
Human Molecular Genetics, 14, 2, pp. 255-65
Human Molecular Genetics, 14, 255-65
Human Molecular Genetics, 14, 255-65
Contains fulltext : 47515.pdf (Publisher’s version ) (Closed access) Retina and retinal pigment epithelium (RPE) belong to the metabolically most active tissues in the human body. Efficient removal of acid load from retina and RPE is a critical fun
Publikováno v:
Vision Research. 44(21):2467-2474
Although the RCS rat is widely used as a model of progressive photoreceptor loss, it is unclear how the relative rod and cone functions change with age. Rod and cone b-waves were isolated using a double flash ERG paradigm. In contrast to cones, rods
Publikováno v:
Vision Research. 44:9-18
Dark-adapted full field electroretinogram (ERG) and visual receptive field thresholds (recorded from the superior colliculus) were correlated in a model of retinal degeneration, the Royal College of Surgeons rat. In both untreated and retinal pigment
Publikováno v:
Neuroscience. 114:389-401
The dystrophic RCS rat undergoes progressive photoreceptor degeneration due to a primary defect in retinal pigment epithelial (RPE) cells. This has a major impact on central visual responsiveness. Here we have examined how functional deterioration is
Publikováno v:
Experimental Neurology. 154:560-572
The functional reinnervation of the olivary pretectal nucleus (OPN) was studied in adult rats with peripheral nerve (PN) grafts bridging the interrupted retinopretectal pathway. Functional recovery was assessed quantitatively using established pupill
Autor:
Peter J. Coffey, Raymond D. Lund, Y. Sauve, S.J.O. Whiteley, M. P. Villegas-Pérez, J. M. Lawrence, T.M. Litchfield
Publikováno v:
Eye. 12:597-604
The Royal College of Surgeons rat provides a valuable animal model for examining the ontogeny of inherited or acquired photoreceptor degeneration and for assessing various treatment paradigms. Here we describe a sequence of events in which photorecep
Publikováno v:
The Journal of Neuroscience. 15:665-675
Regenerated synaptic connections in the damaged mammalian visual system were studied in adult hamsters in which retinal ganglion cells (RGCs) regrew their axons through autologous peripheral nerve grafts directed from the stump of the transected opti
Publikováno v:
Neuroscience. 60:809-823
A primary neuronal culture was prepared from the ventral mesencephalon, centered on the A8, A9 and A10 dopaminergic nuclei of the embryonic day 14 rat, and studied from 12 h to 28 days. At 12 h after plating, and before cell death ensued, 95% of the