Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Y. S. SANGHVI"'
1
LARGE-SCALE SYNTHESIS OF 'Cpep' RNA MONOMERS AND THEIR APPLICATION IN AUTOMATED RNA SYNTHESIS
Autor: Richard T. Pon, Shuyuan Yu, B. Kulkarni, T. Prabhavalkar, T. Mishra, Y. S. Sanghvi
Publikováno v: Nucleosides, Nucleotides & Nucleic Acids. 24:777-781
Small interfering RNAs (siRNA) are the latest candidates for oligonucleotide-based therapeutics. Should siRNA be successful in clinical trials, a huge demand for synthetic RNA is anticipated. We believe that 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d46ce3d798e3e432d67008dcb2b80b
https://doi.org/10.1081/ncn-200060150
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3
Purification of antisense oligonucleotides
Autor: R R, Deshmukh, D L, Cole, Y S, Sanghvi
Publikováno v: Methods in enzymology. 313
Chromatography is an effective tool for obtaining high-purity synthetic oligonucleotides for a variety of end uses, including antisense drug therapy. Reversed-phase and anion-exchange chromatographies are widely used techniques for this application.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9fb4994492a4f153706dcaed5baef136
https://pubmed.ncbi.nlm.nih.gov/10595358
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4
Conformational studies of antisense DNA by PFG NMR
Autor: X, Yang, Y S, Sanghvi, X, Gao
Publikováno v: Journal of biomolecular NMR. 10(4)
Pulsed field gradient diffusion constant measurements were used to resolve the ambiguity in determining the conformational states of single-stranded DNA dodecanucleotides (d1s, d4s and d5s). For d1s and d5s, because of the spectral symmetry conventio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02ebef9c29d1b4006b5c63ca307a852d
https://pubmed.ncbi.nlm.nih.gov/9460243
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5
Reusable Solid-Phase Supports for Oligonucleotide Synthesis Using Hydroquinone-O,O'-diacetic Acid ('Q-Linker')
Autor: Shuyuan Yu, R. T. Pon, X. Yang, Y. S. Sanghvi, Z. Guo
Publikováno v: Nucleosides and Nucleotides. 18:1237-1238
Reusable solid-phase supports for large scale oligonucleotide synthesis have been prepared by converting amino derivatized supports into hydroxyl supports. Rapid nucleo side attachment, via a Q-linker arm, was automatically performed on the DNA synth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::189c24ce9f374b430996b911a55cfc1e
https://doi.org/10.1080/07328319908044674
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6
Stereoselective epoxidation of 3-trans-benzylideneisoborneol
Autor: A. S. Rao, Y. S. Sanghvi
Publikováno v: Journal of Heterocyclic Chemistry. 21:317-320
Epoxydation du benzylidene-2 cyclopentanol en trans phenyl-2 oxa-2spiro [2.4] heptanol-4 avec l'hydroperoxyde t-butyle en presence de vanadium (reactif A) ou avec l'acide m-chloroperbenzoique (reactif B); l'epoxydation stereoselective du trans-benzyl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15801195d8af1f1fcbcbb70c96162c6c
https://doi.org/10.1002/jhet.5570210209
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7
Synthesis and transformations of (±)-trans-4aβ(H), saα(H)-octahydro-4α,7β-dimethyl-2H-1-benzopyran-2-one
Autor: Y. S. Sanghvi, A. S. Rao
Publikováno v: Journal of Heterocyclic Chemistry. 19:1377-1380
Hydrogenation of 4,7-dimethylcoumarin (1) in alkaline medium has been shown to furnish a mixture of (±)-trans-4aβ(H),8aα(H)-octahydro-4α,7β-dimethyl-2H-1-benzopyran-2-one (2), (±)-trans-4aβ(H),8aα(H)-octahydro-4α,7α-dimethyl-2H-1-benzopyran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28f6c84f6683de3c4ecf0390c81c776f
https://doi.org/10.1002/jhet.5570190624
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