Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Y. Robert Li"'
Publikováno v:
Molecular and Cellular Biochemistry. 477:1499-1506
Previously, we reported that 3H-1,2-dithiole-3-thione (D3T), an Nrf2 activator, acted as a potential chemoprotectant against lipopolysaccharide (LPS)-induced mortality in mice. In view of the critical involvement of macrophages in the pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613fcfdc7397f14aa7a0de0ac1ae5e72
https://doi.org/10.1007/s11010-021-04331-x
https://doi.org/10.1007/s11010-021-04331-x
Autor:
Hong Zhu, Y. Robert Li
Publikováno v:
Mol Cell Biochem
Cerium oxide nanoparticles, also known as nanoceria, possess antioxidative and anti-inflammatory activities in animal models of inflammatory disorders, such as sepsis. However, it remains unclear how nanoceria affect cellular superoxide fluxes in mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7b87c1d2835d7d5d106d940986a608
https://doi.org/10.1007/s11010-021-04246-7
https://doi.org/10.1007/s11010-021-04246-7
Autor:
Y. Robert Li, Hong Zhu
Publikováno v:
Molecular and Cellular Biochemistry
Vitamin C, also known as ascorbic acid or ascorbate, is a water-soluble vitamin synthesized in plants as well as in animals except humans and several other animal species. Humans obtain vitamin C from dietary sources and via vitamin supplementation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0fa84ab1d552993c123c8242f6ed1d
http://europepmc.org/articles/PMC8413356
http://europepmc.org/articles/PMC8413356
Autor:
Zhenquan Jia, Hong Zhu, Xiaolun Sun, Y. Robert Li, Ho Young Lee, Gabriella Gaje, Ashkon Koucheki, Halley Shukla, Humaira A. Bibi
Publikováno v:
Molecular and Cellular Biochemistry. 474:27-39
Epidemiological studies have exhibited a strong correlation between exposure to air pollution and deaths due to vascular diseases such as atherosclerosis. Benzo-a-pyrene-1,6-quinone (BP-1,6-Q) is one of the components of air pollution. This study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eceec8cece9a706712621d58fcc3c549
https://doi.org/10.1007/s11010-020-03831-6
https://doi.org/10.1007/s11010-020-03831-6
Publikováno v:
Cardiovascular Toxicology. 20:448-453
Peroxiredoxin (Prx) refers to a family of thiol-dependent peroxidases that decompose hydrogen peroxide, lipid hydroperoxides, as well as peroxynitrite, and protect against oxidative and inflammatory stress. There are six mammalian Prx isozymes (Prx1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac283e2ce173454f3ef1777ee75fdf6d
https://doi.org/10.1007/s12012-020-09588-0
https://doi.org/10.1007/s12012-020-09588-0
Autor:
Zhenquan Jia, Gabriella Gaje, Michael A. Trush, Rojin Chitrakar, Halley Shukla, Humaira A. Bibi, Y. Robert Li, Hong Zhu, Ashkon Koucheki
Publikováno v:
Toxicology Letters. 322:120-130
Strong epidemiological evidence supports the association between increased air pollution and the risk of developing atherosclerotic cardiovascular diseases (CVDs). However, the mechanism remains unclear. As an environmental air pollutant and benzo-a-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b9dd86222244229d5b06df5e8e6fbd
https://doi.org/10.1016/j.toxlet.2020.01.011
https://doi.org/10.1016/j.toxlet.2020.01.011
Previously, we reported that 3H-1,2-dithiole-3-thione (D3T), an Nrf2 activator, acted as a potential chemoprotectant against lipopolysaccharide (LPS)-induced mortality in mice. In view of the critical involvement of macrophages in the pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd5fa30c455874c5410fb2d782e778d
https://doi.org/10.21203/rs.3.rs-726414/v1
https://doi.org/10.21203/rs.3.rs-726414/v1
Autor:
Halley Shukla, Zhenquan Jia, Y. Robert Li, Ho Young Lee, Michael A. Trush, Xiaolun Sun, Hong Zhu, Gabriella Gaje, Ashkon Koucheki
Publikováno v:
Toxicology and applied pharmacology. 404
Numerous studies conducted in the past have reported deaths in the human population due to cardiovascular diseases (CVD) on exposure to air particulate matter (APM). BP-1,6-quinone (BP-1,6-Q) is one of the significant components of APM. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0e0d7d29821e2e1610d3fae0c085f0
https://pubmed.ncbi.nlm.nih.gov/32739527
https://pubmed.ncbi.nlm.nih.gov/32739527
Publikováno v:
Reactive oxygen species (Apex, N.C.). 8(24)
Regulation of antioxidant gene expression is essential for controlling oxidative stress and maintaining physiological homeostasis. In this context, the nuclear factor E2-related factor 2 (Nrf2) has been identified as the chief regulator of the transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871691776e5722671aae18d756dbc36b
https://pubmed.ncbi.nlm.nih.gov/31692987
https://pubmed.ncbi.nlm.nih.gov/31692987
While it is well known that bacterial infection is the predominant cause of sepsis, the molecular pathophysiology of this clinical syndrome remains ill-defined. In this Research Highlights article, we discuss the recent research findings regarding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d94665a2fa32225237b4987fa5237a5
https://europepmc.org/articles/PMC6519466/
https://europepmc.org/articles/PMC6519466/