Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Y. Renee Lea-Currie"'
Autor:
Deborah M. Muoio, Y. Renee Lea-Currie, Benjamin M. Buehrer, William E. Kraus, Robert Stevens, James B. Nicoll, Joseph A. Houmard, Karen Everingham, Jean Paul Kovalik, Dorothy H. Slentz, C. Lawrence Kien
Publikováno v:
Diabetes
OBJECTIVE Adipocyte infiltration of the musculoskeletal system is well recognized as a hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a benign storage site for surplus lipid or play a role in disrupting energ
Autor:
Yuan-Di C. Halvorsen, Jeffrey M. Gimble, Dawn M. Franklin, Y. Renee Lea-Currie, Anindita Sen, William O. Wilkison, Danuta Sujkowska
Publikováno v:
Journal of Cellular Biochemistry. 81:312-319
The current study was done to assess if heterogeneity existed in the degree of adipogenesis in stromal cells (preadipocytes) from multiple donors. In addition to conventional lipid-based methods, we have employed a novel signal amplification technolo
Autor:
Y. Renee Lea-Currie, Jacqueline M. Stephens, David M. Ribnicky, Duffin David J, William T. Cefalu, Ilya Raskin, Jeffrey M. Gimble, Benjamin M. Buehrer
Plant extracts continue to represent an untapped source of renewable therapeutic compounds for the treatment and prevention of illnesses including chronic metabolic disorders. With the increase in worldwide obesity and its related morbidities, the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4984988b7101d16ca9236390d9162464
https://europepmc.org/articles/PMC3154462/
https://europepmc.org/articles/PMC3154462/
Use of Adipose-Derived Stem Cells in High-Throughput Screening to Identify Modulators of Lipogenesis
Publikováno v:
Adipose-Derived Stem Cells ISBN: 9781617379598
Drug discovery efforts have an increasing focus on functional cell-based screening to identify compounds that modulate targets presented in a relevant format. Historically, immortalized cell lines have been used in primary and secondary screens due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84797da4c2af920b74e6d1b1a4ab319a
https://doi.org/10.1007/978-1-61737-960-4_26
https://doi.org/10.1007/978-1-61737-960-4_26
Autor:
Yuan-Di C. Halvorsen, Dawn M. Franklin, Jeffrey M. Gimble, Y. Renee Lea-Currie, Arden L. Bond, Anindita Sen, William O. Wilkison, Danuta Sujkowski, P.Nicole Ellis
Publikováno v:
Metabolism: clinical and experimental. 50(4)
While adipocyte differentiation has been studied extensively in murine cultures, the lack of a readily available preadipocyte model has hindered equivalent studies in man. We describe methods for the isolation and culture of primary human stromal cel