Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Y. Ramanathan"'
Autor:
Guochang Huang, Andrew J Kaufman, Russell J H Ryan, Yevgeniy Romin, Laryssa Huryn, Sarina Bains, Katia Manova-Todorova, Patricia L Morris, Gary R Hunnicutt, Carrie A Adelman, John H J Petrini, Y Ramanathan, Bhuvanesh Singh
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209995 (2019)
Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family members. Targeted inactivation of DCUN1D1 in mice results in male-specific i
Externí odkaz:
https://doaj.org/article/b2c5cb5ef6f94ce8bb3cf00f8422e4c2
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 113K, Supplementary Table S1. Oral squamous cell carcinoma- patient and tumor characteristics. Supplementary Table S2. Lung squamous cell carcinoma -patient and tumor characteristics. Supplementary Table S3. Thyroid Carcinoma -patient and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156b6f220c108ea13157d0d6a6c0a1c7
https://doi.org/10.1158/1078-0432.22450373
https://doi.org/10.1158/1078-0432.22450373
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 918K, A, Schematic representation of domain structures of SCCRO and its paralogues. B, Alignment of PONY domain of SCCRO and its paralogues. SCCRO5 residues critical for binding to neddylation components are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c067846cf152f579acfcaf50691b52
https://doi.org/10.1158/1078-0432.22450388
https://doi.org/10.1158/1078-0432.22450388
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
Purpose: To determine mechanisms by which SCCRO5 (aka DCUN1D5) promotes oncogenesis.Experimental Design:SCCRO5 mRNA and protein expression were assessed in 203 randomly selected primary cancer tissue samples, matched histologically normal tissues, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ddc22c008dea913a9ccf460f758aa2
https://doi.org/10.1158/1078-0432.c.6521921.v1
https://doi.org/10.1158/1078-0432.c.6521921.v1
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 56K, Correlation between SCCRO5 copy number alterations and mRNA expression measured by RNA seq (deep sequencing for RNA), in head and neck squamous cell carcinomas from The Cancer Genome Atlas, normalized by z-score transformation. Het, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c812ffa56055e44b6dca107f8cdf1c20
https://doi.org/10.1158/1078-0432.22450382.v1
https://doi.org/10.1158/1078-0432.22450382.v1
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 840K, A, Western blot analysis of lysates of NIH-3T3 cells stably transfected with vector alone, SCCRO5, SCCRO5_∆1-10 or SCCRO5_D195N/A219R/D225N and probed with antibody against SCCRO5 or tubulin as a loading control. SCCRO5_∆1-10 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cac495e1bfc6f5f0f8ed3b93af0a61
https://doi.org/10.1158/1078-0432.22450385.v1
https://doi.org/10.1158/1078-0432.22450385.v1
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 77K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d8512f9a1e5ebdb46db924976001ca
https://doi.org/10.1158/1078-0432.22450376
https://doi.org/10.1158/1078-0432.22450376
Autor:
Bhuvanesh Singh, Suresh Y. Ramanathan, Ronald Ghossein, Mithat Gönen, Manish Shaha, Elizabeth Buss, Sarina Bains, Kushyup Shah, Guochang Huang, Víola B. Weeda, Claire C. Bommeljé
PDF file - 76K, Kaplan-Meier survival curves from post-hoc analysis showing recurrence-free survival based on SCCRO5 mRNA expression status in primary lung neuroendocrine carcinomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438dfc04777fb164202b0b9ff59bb462
https://doi.org/10.1158/1078-0432.22450379.v1
https://doi.org/10.1158/1078-0432.22450379.v1
Autor:
Bhuvanesh Singh, Y. Ramanathan, Archontoula Stoffel, Pulivarthi H. Rao, Ronald Ghossein, Russell Ryan, Andrew Kaufman, Maria Dudas, Yoshihiro Yonekawa, Benjamin Lee, Kepal N. Patel, Ellie Maghami, Ivan Ngai, Pabbathi G. Reddy, Simon G. Talbot, Pornchai O-charoenrat, Inderpal Sarkaria
Supplementary Tables 1-3 from Squamous Cell Carcinoma Related Oncogene/DCUN1D1 Is Highly Conserved and Activated by Amplification in Squamous Cell Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427e7a91d3f76fa224cc598b4d407b87
https://doi.org/10.1158/0008-5472.22364889
https://doi.org/10.1158/0008-5472.22364889
Autor:
Bhuvanesh Singh, Y. Ramanathan, Archontoula Stoffel, Pulivarthi H. Rao, Ronald Ghossein, Russell Ryan, Andrew Kaufman, Maria Dudas, Yoshihiro Yonekawa, Benjamin Lee, Kepal N. Patel, Ellie Maghami, Ivan Ngai, Pabbathi G. Reddy, Simon G. Talbot, Pornchai O-charoenrat, Inderpal Sarkaria
Chromosomal amplification at 3q is common to multiple human cancers, but has a specific predilection for squamous cell carcinomas (SCC) of mucosal origin. We identified and characterized a novel oncogene, SCC-related oncogene (SCCRO), which is amplif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c4119f4674030b2704d6dd390f3eb5
https://doi.org/10.1158/0008-5472.c.6494421.v1
https://doi.org/10.1158/0008-5472.c.6494421.v1