Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Y. Phei Lok"'
Autor:
Raju Adhikari, Ezio Rizzardo, Gerard J. Wilson, Saif A. Haque, Matthias Häussler, Scott E. Watkins, Ming Chen, Simon King, Craig M. Forsyth, Y Phei Lok, Jacek J. Jasieniak, Kevin N. Winzenberg
Publikováno v:
Macromolecules. 43:7101-7110
The synthesis of a series of novel, unsymmetrically substituted benzothiadiazole-containing vinyl monomers and their free radical polymerization with and without the control of a reversible addition−fragmentation chain transfer (RAFT) agent is repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d27505442bdd7c7a66e055ed5bec12
https://doi.org/10.1021/ma1008572
https://doi.org/10.1021/ma1008572
Synthesis and biological evaluation of anthranilamide-based non-peptide mimetics of ω-conotoxin GVIA
Autor:
Stewart Forsyth, Peter J. Duggan, Richard J. Lewis, Nicholas E. Shepherd, Christina I. Schroeder, Jonathan B. Baell, Y. Phei Lok
Publikováno v:
Tetrahedron. 62:7284-7292
Non-peptide mimetics based on an anthranilamide 'scaffold' possessing fragments that mimic Lys2, Tyr13 and Arg17 in omega-conotoxin GVIA have been prepared. Compounds were assayed for binding to the voltage-gated calcium channels Ca(v)2.2 ('N-type')
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17e357b298db1cd9c13478dc6732cf2
https://doi.org/10.1016/j.tet.2006.05.041
https://doi.org/10.1016/j.tet.2006.05.041
Autor:
Aijun Yang, Y. Phei Lok, Kellie L. Tuck, Natalie G. Lumsden, Peter J. Duggan, Richard J. Lewis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:2763-2765
We report the synthesis and biological activity of a low molecular weight non-peptidic mimic of the analgesic peptide omega-conotoxin GVIA. The molecular weight of this compound presents a reduction by 193g/mol compared to a previously reported lead.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a219c290b21e9d54b63d675f9d2ddb
https://doi.org/10.1016/j.bmcl.2009.03.130
https://doi.org/10.1016/j.bmcl.2009.03.130
Publikováno v:
ChemInform. 35
ω-Conotoxins are an interesting class of naturally occurring peptides that induce dramatic effects on the central nervous system (CNS). They have been shown to interfere with the normal function of neuronal calcium channels and can act as non-addict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324da0b5be832221e02366196293bc80
https://doi.org/10.1002/chin.200424258
https://doi.org/10.1002/chin.200424258
Autor:
Peter J. Duggan, Stewart Forsyth, Y Phei Lok, Christina I. Schroeder, Jonathan B. Baell, Richard J. Lewis
Publikováno v:
Bioorganicmedicinal chemistry. 12(15)
A benzothiazole-derived compound (4a) designed to mimic the C-alpha-C-beta bond vectors and terminal functionalities of Lys2, TyrI3 and Arg17 in omega-conotoxin GVIA was synthesised, together with analogues (4b-d), which had each side-chain mimic sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aaec8a850eb92672de981b8d984281
https://pubmed.ncbi.nlm.nih.gov/15246080
https://pubmed.ncbi.nlm.nih.gov/15246080
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 59:o1958-o1959
The benzophenone derivative, methyl [2-(3-nitrobenzoyl)benzoylamino]acetate, (3), exists in equilibrium with the title compound, C17H14N2O6, (4), a tricyclic tertiary alcohol, with the position of the equilibrium lying strongly in favour of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2ff7ad1cdc95bc3e3d22a304dbdc9a6
https://doi.org/10.1107/s1600536803025790
https://doi.org/10.1107/s1600536803025790
Autor:
Matthias Häussler, Y. Phei Lok, Ming Chen, Jacek Jasieniak, Raju Adhikari, Simon P. King, Saif A. Haque, Craig M. Forsyth, Kevin Winzenberg, Scott E. Watkins, Ezio Rizzardo, Gerard J. Wilson
Publikováno v:
Macromolecules; Sep2010, Vol. 43 Issue 17, p7101-7110, 10p
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.