Robust GRK2/3/6-dependent desensitization of oxytocin receptor in neurons

Autor: Kiran George, Hanh T.M. Hoang, Taryn Tibbs, Raghavendra Y. Nagaraja, Guangpu Li, Eva Troyano-Rodriguez, Mohiuddin Ahmad

Publikováno v: iScience, Vol 27, Iss 6, Pp 110047- (2024)

Summary: Oxytocin plays critical roles in the brain as a neuromodulator, regulating social and other affective behavior. However, the regulatory mechanisms controlling oxytocin receptor (OXTR) signaling in neurons remain unexplored. In this study, we

Externí odkaz: https://doaj.org/article/46822e0bd3b34225849078ff1d0754ad

Cholinergic Homeostatic Synaptic Plasticity Drives the Progression of Aβ-Induced Changes in Neural Activity

Autor: Eu-Teum Hahm, Raghavendra Y. Nagaraja, Girma Waro, Susan Tsunoda

Publikováno v: Cell Reports, Vol 24, Iss 2, Pp 342-354 (2018)

Summary: Homeostatic synaptic plasticity (HSP) is the ability of neurons to exert compensatory changes in response to altered neural activity. How pathologically induced activity changes are intertwined with HSP mechanisms is unclear. We show that, i

Externí odkaz: https://doaj.org/article/0e0a9619715f4018bb0bd4485c42bbd7

Selective Ablation of Sod2 in Astrocytes Induces Sex-Specific Effects on Cognitive Function, d-Serine Availability, and Astrogliosis

Autor: Matthew P. Baier, Raghavendra Y. Nagaraja, Hannah P. Yarbrough, Daniel B. Owen, Anthony M. Masingale, Rojina Ranjit, Megan A. Stiles, Ashley Murphy, Martin-Paul Agbaga, Mohiuddin Ahmad, David M. Sherry, Michael T. Kinter, Holly Van Remmen, Sreemathi Logan

Publikováno v: J Neurosci

Cognitive decline is a debilitating aspect of aging and neurodegenerative diseases such as Alzheimer's disease are closely associated with mitochondrial dysfunction, increased reactive oxygen species, neuroinflammation, and astrogliosis. This study i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c4a2c5359ec3d859537535e76c84c5
https://europepmc.org/articles/PMC9351643/

The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABAA Receptors, Boosts Functional Recovery after Stroke

Autor: Julien Chuquet, Andrew N. Clarkson, Ann-Britt Marcher, Katarzyna Gach-Janczak, Mahmoud Hazime, David Vaudry, Julie Maucotel, Katia Lehongre, Benjamin Lefranc, Pascale P. Quilichini, Raghavendra Y. Nagaraja, Emma K. Gowing, Susanne Mandrup, Rhita Lamtahri, Jérôme Leprince, Michael Alasoadura

Publikováno v: Lamtahri, R, Hazime, M, Gowing, E K, Nagaraja, R Y, Maucotel, J, Alasoadura, M, Quilichini, P P, Lehongre, K, Lefranc, B, Gach-Janczak, K, Marcher, A B, Mandrup, S, Vaudry, D, Clarkson, A N, Leprince, J & Chuquet, J 2021, ' The gliopeptide ODN, a ligand for the benzodiazepine site of GABA A receptors, boosts functional recovery after stroke ', Journal of Neuroscience, vol. 41, no. 33, pp. 7148-7159 . https://doi.org/10.1523/JNEUROSCI.2255-20.2021
Journal of Neuroscience
Journal of Neuroscience, 2021, 41 (33), pp.7148-7159. ⟨10.1523/JNEUROSCI.2255-20.2021⟩

Following stroke, the survival of neurons and their ability to re-establish connections is critical to functional recovery. This is strongly influenced by the balance between neuronal excitation and inhibition. In the acute phase of experimental stro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25649e49dc0582c0ff69b132fd0af09a
https://doi.org/10.1523/jneurosci.2255-20.2021

Optimal distributed control of renewable energy-based microgrid – an energy management approach

Autor: T. Devaraju, M. Vijaykumar, Y. Nagaraja

Publikováno v: International Journal of Ambient Energy. 42:1635-1642

This article proposes an optimal control for renewable energy-based microgrid. The proposed microgrid is composed of the solar photovoltaic systems (SPV), battery energy storage system (BESS) at bu...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c634efcdbde60191ca6730a491ae1b58
https://doi.org/10.1080/01430750.2019.1611660