Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Y. Loosli"'
Autor:
Y. Loosli, R. Luginbuehl, Céline Labouesse, Jess G. Snedeker, Benoît Vianay, Jean-Jacques Meister
Publikováno v:
Integrative Biology. 5:865-876
The mechanical coupling between adherent cells and their substrates is a major driver of downstream behavior. This coupling relies on the formation of adhesion sites and actin bundles. How cells generate these elements remains only partly understood.
Publikováno v:
Soft Matter. 8:673-681
Polydimethylsiloxane (PDMS) is a bioinert synthetic polymer with tunable elastic properties that is commonly used as a cell culture substrate. Although plasma treatments are widely used to bio-functionalize otherwise hydrophobic PDMS surfaces, plasma
Publikováno v:
Acta Biomaterialia. 7:478-484
Hundreds of studies have been devoted to the search for the ideal architecture for bone scaffold. Despite these efforts, results are often contradictory, and rules derived from these studies are accordingly vague. In fact, there is enough evidence to
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 4(5)
We present a novel approach to modeling cell spreading, and use it to reveal a potentially central mechanism regulating focal adhesion maturation in various cell phenotypes. Actin bundles that span neighboring focal complexes at the lamellipodium-lam
Publikováno v:
The British journal of oralmaxillofacial surgery. 51(7)
Uninterrupted resection of mandibular bone is often necessary during maxillofacial operations for cancer. This weakens the mandible, and increases the risk of fracture. To our knowledge no biomechanical analysis has been made of deformations and stra
Publikováno v:
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 368(1920)
Predictive numerical models of cellular response to biophysical cues have emerged as a useful quantitative tool for cell biology research. Cellular experimentsin silicocan augmentin vitroandin vivoinvestigations by filling gaps in what is possible to
Publikováno v:
Biophysical Journal. 100(3):611a-612a
After an initial phase of non-specific interactions with an adhesive substrate, cells enter a rapid phase of spreading. During this phase, unstable entities (focal complexes -FXs- and actin bundles) selectively mature into long lasting focal adhesion
Publikováno v:
Biophysical Journal. 100:599a
A correlative link between decreased cancer cell stiffness and increased aggressiveness (metatstatic potential) has been established in a wide range of cancers, such as leukemia, breast cancer and chondrosarcoma. Nearly all studies establishing this
Autor:
Y. Loosli
Publikováno v:
Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences; Jun2010, Vol. 368 Issue 1920, p2629-2652, 24p
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.