Zobrazeno 1 - 10 of 180 pro vyhledávání: '"Y. Larsen"'
1
Akademický článek
Layer III pyramidal cells in the prefrontal cortex reveal morphological changes in subjects with depression, schizophrenia, and suicide
Autor: Nick Y. Larsen, Ninna Vihrs, Jesper Møller, Jon Sporring, Xueke Tan, Xixia Li, Gang Ji, Grazyna Rajkowska, Fei Sun, Jens R. Nyengaard
Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Brodmann Area 46 (BA46) has long been regarded as a hotspot of disease pathology in individuals with schizophrenia (SCH) and major depressive disorder (MDD). Pyramidal neurons in layer III of the Brodmann Area 46 (BA46) project to other cort
Externí odkaz: https://doaj.org/article/5b14b2a3b9a147ffa7231645403b8830
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2
Akademický článek
Cellular 3D-reconstruction and analysis in the human cerebral cortex using automatic serial sections
Autor: Nick Y. Larsen, Xixia Li, Xueke Tan, Gang Ji, Jing Lin, Grazyna Rajkowska, Jesper Møller, Ninna Vihrs, Jon Sporring, Fei Sun, Jens R. Nyengaard
Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Nick Larsen et al. developed a pipeline to collect and image serial sections from fixed human cortex, then apply deep learning to detect pyramidal cells from 3D reconstructions of these sections. Their results reiterate that cortical pyramidal cells
Externí odkaz: https://doaj.org/article/c372f12dc5a442998736c0ade347fe0e
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4
Evaluating Pediatric Sepsis Definitions Designed for Electronic Health Record Extraction and Multicenter Quality Improvement*
Autor: Holly Depinet, Heidi Gruhler, Gitte Y. Larsen, Halden F. Scott, Ruth Riggs, W. Charles Huskins, Richard J. Brilli, Charles G. Macias, Matthew Niedner, Troy Richardson, Fran Balamuth, Raina Paul
Publikováno v: Critical Care Medicine. 48:e916-e926
Objectives To describe the Children's Hospital Association's Improving Pediatric Sepsis Outcomes sepsis definitions and the identified patients; evaluate the definition using a published framework for evaluating sepsis definitions. Design Observation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa4c0c5936888bd74455e0bdad49258
https://doi.org/10.1097/ccm.0000000000004505
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5
Akademický článek
Early Combination of Material Characteristics and Toxicology Is Useful in the Design of Low Toxicity Carbon Nanofiber
Autor: Tore Syversen, Calin D. Marioara, Unni C. Nygaard, Ellen K. Jensen, Sten Y. Larsen
Publikováno v: Materials, Vol 5, Iss 9, Pp 1560-1580 (2012)
This paper describes an approach for the early combination of material characterization and toxicology testing in order to design carbon nanofiber (CNF) with low toxicity. The aim was to investigate how the adjustment of production parameters and pur
Externí odkaz: https://doaj.org/article/0e3d183595ec46679984efd7cc1648b1
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6
Cellular 3D-reconstruction and analysis in the human cerebral cortex using automatic serial sections
Autor: Jens R. Nyengaard, Jesper Møller, Ninna Vihrs, Xixia Li, Jing Lin, Fei Sun, Xueke Tan, Jon Sporring, Gang Ji, Nick Y. Larsen, Grazyna Rajkowska
Publikováno v: Larsen, N Y, Li, X, Tan, X, Ji, G, Lin, J, Rajkowska, G, Møller, J, Vihrs, N, Sporring, J, Sun, F & Nyengaard, J R 2021, ' Cellular 3D-reconstruction and analysis in the human cerebral cortex using automatic serial sections ', Communications Biology, vol. 4, no. 1, 1030 . https://doi.org/10.1038/s42003-021-02548-6
Communications Biology
Larsen, N Y, LI, X, Tan, X, Ji, G, Lin, J, Rajkowska, G, Møller, J, Vihrs, N, Sporring, J, Sun, F & Nyengaard, J R 2021, ' Cellular 3D-reconstruction and analysis in the human cerebral cortex using automatic serial sections ', Communications Biology, vol. 4, no. 1, 1030 . https://doi.org/10.1038/s42003-021-02548-6
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Techniques involving three-dimensional (3D) tissue structure reconstruction and analysis provide a better understanding of changes in molecules and function. We have developed AutoCUTS-LM, an automated system that allows the latest advances in 3D tis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65c23f28f66a435fff3d352db73de97
https://curis.ku.dk/ws/files/281711881/Cellular_3D_reconstruction_and_analysis_in_the_human_cerebral_cortex_using_automatic_serial_sections.pdf
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7
Akademický článek
Stereological estimation of particle shape from vertical sections.
Autor: Y. LARSEN, NICK1,2,3 (AUTHOR) nylarsen@clin.au.dk, ZIEGEL, JOHANNA F.1,4 (AUTHOR), NYENGAARD, JENS R.1,2,3 (AUTHOR), JENSEN, EVA B. VEDEL1,5 (AUTHOR)
Publikováno v: Journal of Microscopy. Sep2019, Vol. 275 Issue 3, p183-194. 12p. 2 Color Photographs, 1 Black and White Photograph, 4 Diagrams, 7 Charts, 1 Graph.
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8
Best practices in pediatric sepsis: building and sustaining an evidence-based pediatric sepsis quality improvement program
Autor: Jennifer K. Workman, Gitte Y. Larsen, Christopher Miller, Roni D. Lane, Amber Chambers
Publikováno v: Hosp Pract (1995)
Pediatric sepsis is a common problem worldwide and is associated with significant morbidity and mortality. Best practice recommendations have been published by both the American College of Critical Care Medicine and the Surviving Sepsis Campaign to g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b734002df275519091e640193f36e99e
https://pubmed.ncbi.nlm.nih.gov/34404310
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9
Improving Knowledge of Active Safety and QI Projects Amongst Practitioners in a Pediatric ICU
Autor: Brian F. Flaherty, Kevin Hummel, Senthuran Vijayarajah, Benjamin R. White, Shad Outsen, Gitte Y. Larsen
Publikováno v: Pediatric qualitysafety. 7(3)
The success of quality improvement (QI) projects depends on many factors, with communication and knowledge of project-specific practice change being fundamental. This project aimed to improve the knowledge of active safety and QI projects.Two interve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f33968367ca432d7b0b304034833d0
https://pubmed.ncbi.nlm.nih.gov/35720872
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10
Stereological estimation of particle shape from vertical sections
Autor: Nick Y. Larsen, Eva B. Vedel Jensen, Jens R. Nyengaard, Johanna F. Ziegel
Publikováno v: Larsen, N Y, Ziegel, J F, Nyengaard, J R & Jensen, E B V 2019, ' Stereological estimation of particle shape from vertical sections ', Journal of Microscopy, vol. 275, no. 3, pp. 183-194 . https://doi.org/10.1111/jmi.12826
In the present paper, we describe a new simple stereological method of estimating volume tensors in 3D from vertical sections. The volume tensors provide information about particle shape in 3D. In a model-based setting, the method requires that the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2535a65c422bf2f3c661d85cd7a995cd
https://doi.org/10.1111/jmi.12826
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