QSAR modeling and molecular docking studies of 2-oxo-1, 2-dihydroquinoline-4- carboxylic acid derivatives as p-glycoprotein inhibitors for combating cancer multidrug resistance

Autor: M. Lahyaoui, A. Diane, H. El-Idrissi, T. Saffaj, Y. Kandri Rodi, B. Ihssane

Publikováno v: Heliyon, Vol 9, Iss 1, Pp e13020- (2023)

Multidrug resistance (MDR) proteins related to the ATP-binding cassette family are found in a very wide range of human tumors and result in therapeutic failure. The overexpression of efflux pumps such as ABCB1 is one of the mechanisms of MDR. This pa

Externí odkaz: https://doaj.org/article/280799f344d040d29281ca32a8b517a2

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Study of the inhibition effect of a new cationic surfactant on mild steel corrosion in a 1 M HCl solution

Autor: Y. Kandri Rodi, R. Ghibate, M. K. Skalli, A. Mazzah, A. Haoudi, N. Arrousse, O. Abdellaoui, O. Senhaji, Mustapha Taleb

Publikováno v: Materials Today: Proceedings. 45:7517-7523

6-(2,3-dioxoindolin-1-yl)-N,N,N-trimethylhexan-1-ammonium bromide 3, a cationic surfactant, was synthesized and characterized by different spectroscopic techniques (nuclear magnetic resonance and High-resolution mass spectrometry (1H NMR, 13C NMR, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::613570dc196648c0184b8570e791fe1e
https://doi.org/10.1016/j.matpr.2021.02.316

Crystal structure, Hirshfeld surface analysis and DFT studies of 6-bromo-3-(12-bromododecyl)-2-(4-nitrophenyl)-4H-imidazo[4,5-b]pyridine

Autor: Joel T. Mague, Y. Kandri Rodi, K. Jarmoni, K. Misbahi, Z. Jabri, Tuncer Hökelek, S. Sabir

Publikováno v: Acta Crystallographica Section E: Crystallographic Communications
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 5, Pp 677-682 (2020)

In the title mol­ecule, the imidazolo­pyridine and phenyl rings are nearly co-planar, and the 12-bromo­dodecyl side chain is directed so as to give the complete mol­ecule a V-shape.
The title compound, C24H30Br2N4O2, consists of a 2-(4-nitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a14882af0c3ef64814cd541d97b48fd
https://doi.org/10.1107/s2056989020005228

SYNTHESIS, REACTIVITY AND BIOLOGICAL ACTIVITY OF QUINOXALIN-2-ONE DERIVATIVES

Autor: El Mokhtar Essassi, R. Bouhfid, Y. Kandri Rodi, S. Ferfra, H. Benzeid, Y. Ramli

Publikováno v: Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, Vol 11, Iss 1, Pp 67-90 (2010)

Quinoxalines have a great interest in various fields and particularly in chemistry, biology and pharmacology. It enabled the researchers to develop many methods for their preparations and to seek new fields of application. In this review, we’ll exp

Externí odkaz: https://doaj.org/article/87e5603173454911a5ca1f27258cca32