Zobrazeno 1 - 10
of 849
pro vyhledávání: '"Y. K. Lam"'
Autor:
Bonaventure Y. M. Ip, Bonnie Y. K. Lam, Vincent M. H. Hui, Lisa W. C. Au, Mandy W. T. Liu, Lin Shi, Vivian W. Y. Lee, Winnie C. W. Chu, Thomas W. Leung, Ho Ko, Vincent C. T. Mok
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Cerebral small vessel disease (SVD) is an important cause of dementia that lacks effective treatment. We evaluated the efficacy and safety of cilostazol, an antiplatelet agent with potential neurovascular protective effects, in
Externí odkaz:
https://doaj.org/article/6776c9f0269c4d9395276e1cef5d1921
Autor:
Sayed Mohammad Ebrahim Sahraeian, Ruolin Liu, Bayo Lau, Karl Podesta, Marghoob Mohiyuddin, Hugo Y. K. Lam
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Somatic mutations are crucial to the understanding of cancer genesis, progression, and treatment, but are still challenging to detect. Here the authors present NeuSomatic, a convolutional neural network approach for accurate somatic mutation detectio
Externí odkaz:
https://doaj.org/article/97e2f4d53235488391827e07f5a633f0
Publikováno v:
South Asian Diaspora. :1-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d9371550ea8d216a90051c1e19ed323
https://doi.org/10.1080/19438192.2023.2198337
https://doi.org/10.1080/19438192.2023.2198337
Autor:
Fredric Y. K. Lam, Eric M. Dunham
Publikováno v:
GEOPHYSICS. 88:P15-P36
Numerical modeling is a powerful tool for predicting the acoustic signature of pneumatic marine seismic sources to maximize low-frequency content and minimize excessively high-frequency content that may harm marine life. Idealized source models often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::376c58b8c4956766eade58d9d3e123d2
https://doi.org/10.1190/geo2022-0346.1
https://doi.org/10.1190/geo2022-0346.1
Autor:
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M. Reza Sailani, Jens Frey Halling, Peter Plomgaard, Lasse Maretty, Anders Johannes Hansen, Michael P. Snyder, Henriette Pilegaard, Hugo Y. K. Lam, Birgitte Regenberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Somatic cells can accumulate structural variations such as deletions. Here, Møller et al. show that normal human cells generate large extrachromosomal circular DNAs (eccDNAs), most likely the products of excised DNA, that can be transcriptionally ac
Externí odkaz:
https://doaj.org/article/05b697de38844d63ad7af833e2a47a93
Autor:
Sayed Mohammad Ebrahim Sahraeian, Marghoob Mohiyuddin, Robert Sebra, Hagen Tilgner, Pegah T. Afshar, Kin Fai Au, Narges Bani Asadi, Mark B. Gerstein, Wing Hung Wong, Michael P. Snyder, Eric Schadt, Hugo Y. K. Lam
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
RNA-seq is widely used for transcriptome analysis. Here, the authors analyse a wide spectrum of RNA-seq workflows and present a comprehensive analysis protocol named RNACocktail as well as a computational pipeline leveraging the widely used tools for
Externí odkaz:
https://doaj.org/article/0de7f1d5eb3f4b9daae33212abd18a28
Autor:
Yuan Cai, Xiang Fan, Lei Zhao, Wanting Liu, Yishan Luo, Alexander Yuk Lun Lau, Lisa Wing Chi Au, Lin Shi, Bonnie Y. K. Lam, Ho Ko, Vincent Chung Tong Mok
Publikováno v:
Alzheimer's & Dementia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968667e11dd9fbd50dfe9ef89bf80529
https://doi.org/10.1002/alz.13083
https://doi.org/10.1002/alz.13083
Autor:
Kenneth Idler, Andreas Scherer, Charles Lu, Timothy K. McDaniel, Penelope Duerken-Hughes, K J. Langenbach, Seta Stanbouly, Charles Wang, Victoria Zismann, Keyur Talsania, Leming Shi, Margaret C. Cam, Shamoni Maheshwari, Zhipan Li, Luyao Ren, Petr Vojta, Mehdi Pirooznia, Jonathan J Keats, Rasika Kalamegham, Howard Jacob, Bao Tran, Liz Kerrigan, Baitang Ning, Ene Reimann, Jiri Drabek, Eric F. Donaldson, Zhaowei Yang, Sayed Mohammad Ebrahim Sahraeian, Daoud Meerzaman, Marc Sultan, Jessica Nordlund, Tsai-wei Shen, Sulev Kõks, Christopher E. Mason, Yunfei Guo, Winnie S. Liang, Claudia Catalanotti, Jeffrey M. Trent, Ying Yu, Roderick V. Jensen, Huixiao Hong, Malcolm Moos, Wenming Xiao, Stephen T. Sherry, Jonathan Foox, Joe Shuga, Hugo Y. K. Lam, Chunlin Xiao, Lijing Yao, Li Tai Fang, Wanqiu Chen, Marghoob Mohiyuddin, Monika Mehta, Rebecca Kusko, Roberta Maestro, Yongmei Zhao, Jonathan Adkins, Gary P. Schroth, Daniel Butler, Yuliya Kriga, Ogan D Abaan, Erich Jaeger, Yuanting Zheng, Daniela Gasparotto, Ulrika Liljedahl, Tiffany Hung, Eric Peters, Erica Tassone, Maryellen de Mars, Cu Nguyen, Lei Song, Bin Zhu, Weida Tong, Zivana Tezak, Justin B. Lack, Virginie Petitjean, Jyoti Shetty, Jing Li, Zhong Chen
Publikováno v:
Nat Biotechnol
The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algorithms limits the implementation and uptake of cancer genomics. Here, we describe reference call sets o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7493faa3e6e5450b6b7b28c6727752
https://doi.org/10.1038/s41587-021-00993-6
https://doi.org/10.1038/s41587-021-00993-6
Autor:
Adrian Wong, Alexander Y L Lau, Eugene Lo, Michael Tang, Zhaolu Wang, Wenyan Liu, Nicole Tanner, Natalie Chau, Lorraine Law, Lin Shi, Winnie C W Chu, Jie Yang, Yun-Yun Xiong, Bonnie Y K Lam, Lisa Au, Anne Y Y Chan, Yannie Soo, Thomas W H Leung, Lawrence K S Wong, Linda C W Lam, Vincent C T Mok
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159952 (2016)
Leisure activity participation has been shown to lower risks of cognitive decline in non-stroke populations. However, effects of leisure activities participation upon cognitive functions and risk of dementia after stroke are unclear. The purpose of t
Externí odkaz:
https://doaj.org/article/8a40ba6f66e04e9d999c8d3541b65678
Autor:
Adrian Wong, Alexander Y L Lau, Jie Yang, Zhaolu Wang, Wenyan Liu, Bonnie Y K Lam, Lisa Au, Lin Shi, Defeng Wang, Winnie C W Chu, Yun-Yun Xiong, Eugene S K Lo, Lorraine S N Law, Thomas W H Leung, Linda C W Lam, Anne Y Y Chan, Yannie O Y Soo, Eric Y L Leung, Lawrence K S Wong, Vincent C T Mok
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162846 (2016)
BACKGROUND:The objectives of this study are 1) to examine the frequencies of neuropsychiatric symptom clusters in patients with stroke or transient ischemic attack (TIA) by cognitive level and stroke subtype; and 2) to evaluate effect of demographic,
Externí odkaz:
https://doaj.org/article/ff34876d1e184882a6383c18f30da6b2