Effective and Rapid Osteoclast Inhibition by Denosumab, is Reflected in Serum C Telopeptide (CTX), Across Different Tumor Types

Autor: null S. Tuyls, null F. Geurs, null Y. Deprest

Publikováno v: Journal of Analytical Oncology. 2

Denosumab, a monoclonal antibody against RANKL has superior efficacy against bone metastases. Its in vivo activity can be measured recently by dosing of serum C telopeptide, produced by collagen destruction by the osteoclast. We report the first pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04998b359a8ec184436ea4175a4f227e
https://doi.org/10.6000/1927-7229.2013.02.02.1

Significant pain relief with loading dose zoledronic acid in bone metastases is only seen in patients with elevated initial serum C telopeptide (CTX)

Autor: F. Geurs, R De Loecker, Y Deprest, J Dekoninck

Publikováno v: Pragmatic and Observational Research

J Dekoninck1, F Geurs1, R De Loecker2, Y Deprest21Department of Medical Oncology, 2Laboratory, Regional Hospital Sint Maria, Halle, BelgiumAbstract: In symptomatic bone metastases with significant pain, refractory to standard analgesics and radiother

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277fa50aa18e4c9e0ba4a17a090f1131
https://doi.org/10.2147/por.s15391

Significant pain relief with loading dose zoledronic acid in bone metastases is only seen in patients with elevated initial serum C telopeptide (CTX).

Autor: Dekoninck J; Department of Medical Oncology., Geurs F; Department of Medical Oncology., De Loecker R; Laboratory, Regional Hospital Sint Maria, Halle, Belgium., Deprest Y; Laboratory, Regional Hospital Sint Maria, Halle, Belgium.

Publikováno v: Pragmatic and observational research [Pragmat Obs Res] 2011 Jul 27; Vol. 2, pp. 13-18. Date of Electronic Publication: 2011 Jul 27 (Print Publication: 2011).