Zn/ZnBr2 Catalysed Reaction of Aldehydes with Allylbromide: Synthesis of 2,6-Disubstituted 4-Bromotetrahydropyrans

Autor: D. O. Biradar, Y. D. Mane, Y. P. Sarnikar, S. G. Kulkarni, B. V. Subba Reddy, A. Venkat Narsaiah

Publikováno v: SynOpen, Vol 06, Iss 04, Pp 263-269 (2022)

An efficient approach for the one-pot synthesis of 4-bromotetrahydropyrans in a highly diastereoselective manner via the alkynylation followed by Prins cyclisation is described. The method employs aldehydes and allyl bromide as reactants, with a Zn/Z

Externí odkaz: https://doaj.org/article/1716682c0a5a4955b96f4b0838f0c0d7

Identification of potential biogenic chalcones against antibiotic resistant efflux pump (AcrB) via computational study.

Autor: Rathod S; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India., Dey S; Department of Biotechnology, Indian Institute of Technology, Hyderabad, Kandi, Sangareddy, Telangana, India., Pawar S; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India., Dhavale R; Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India., Choudhari P; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India., Rajakumara E; Department of Biotechnology, Indian Institute of Technology, Hyderabad, Kandi, Sangareddy, Telangana, India., Mahuli D; Department of Pharmacology, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India., Bhagwat D; Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India., Tamboli Y; King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Sankpal P; Department of Pharmaceutical Chemistry, Ashokrao Mane College of Pharmacy, Kolhapur, MS, India., Mali S; Department of Pharmaceutics, Y. D. Mane College of Pharmacy, Kagal, MS, India Kolhapur., More H; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, MS, India.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Jul; Vol. 42 (10), pp. 5178-5196. Date of Electronic Publication: 2023 Jun 20.