Zobrazeno 1 - 10
of 1 823
pro vyhledávání: '"Y. Chin"'
Autor:
Will HG Cheng, Weinan Dong, Emily TY Tse, Carlos KH Wong, Weng Y Chin, Laura E Bedford, Daniel YT Fong, Welchie WK Ko, David VK Chao, Kathryn CB Tan, Cindy LK Lam
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 9, Pp 1317-1325 (2024)
ABSTRACT Aims/Introduction Two Hong Kong Chinese non‐laboratory‐based prediabetes/diabetes mellitus (pre‐DM/DM) risk models were developed using logistic regression (LR) and machine learning, respectively. We aimed to evaluate the models' valid
Externí odkaz:
https://doaj.org/article/8827314f1b724640b05af19e1d064415
Autor:
Hongjia Zhang, Xueqian Sun, Zhanming Li, Tingting Liu, Fang Zhang, Xinyu Meng, Kaimi Li, Jianhua Xu, Wei He, Bo Jing, Tong Wang, Na Ni, Beibei Sun, Feng Yao, Yadi Wu, Qi Wang, Jing Du, Eugene Y. Chin, Binhua P. Zhou, Ping Jiang, Lishun Wang, Jiong Deng
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 100999- (2024)
Externí odkaz:
https://doaj.org/article/bcc91c5524ab4ec9ac6d6e3c5d071f75
Autor:
Will H. G. Cheng, Weinan Dong, Emily T. Y. Tse, Linda Chan, Carlos K. H. Wong, Weng Y. Chin, Laura E. Bedford, Wai Kit Ko, David V. K. Chao, Kathryn C. B. Tan, Cindy L. K. Lam
Publikováno v:
Journal of Primary Care & Community Health, Vol 15 (2024)
Introduction/Objectives: A non-laboratory-based pre-diabetes/diabetes mellitus (pre-DM/DM) risk prediction model developed from the Hong Kong Chinese population showed good external discrimination in a primary care (PC) population, but the estimated
Externí odkaz:
https://doaj.org/article/b60a8a8a82464c27ad4e7f1ca7373e75
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Polymyxin-induced neuromuscular blockade is a rare but potentially fatal condition, with majority of cases that were reported between 1962 and 1973. We describe a patient who developed hypercapnic respiratory failure after initiation of polymyxin for
Externí odkaz:
https://doaj.org/article/1188e3fd80e749a2ad2def2c5cd57e67
Publikováno v:
ELT Worldwide: Journal of English Language Teaching, Vol 10, Iss 1, Pp 104-121 (2023)
Form-focused deductive grammar learning approach is an effective way to facilitate language learners to memorize atomistic grammatical rules. However, beyond retaining isolated grammar rules, learners can benefit from using web based concept map, a v
Externí odkaz:
https://doaj.org/article/05df3d548f924cd29c0c8bbd729b1c4c
Autor:
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, o
Externí odkaz:
https://doaj.org/article/ef7fee6301d340c5b67edc494cc4b801
Autor:
Xinying Jia, Yanni K.-Y. Chin, Alan H. Zhang, Theo Crawford, Yifei Zhu, Nicholas L. Fletcher, Zihan Zhou, Brett R. Hamilton, Martin Stroet, Kristofer J. Thurecht, Mehdi Mobli
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Head-to-tail macrocyclization of proteins and peptides can increase their structural stability, however, potential polymerization can lead to reduced yields. Here, the authors report the engineering of self-cyclizing ‘autocyclase’ proteins to gen
Externí odkaz:
https://doaj.org/article/e22b7329d2fa42c78900ee527f8a1241
Autor:
Michael J. Maxwell, Chris Thekkedam, Cedric Lamboley, Yanni K.-Y. Chin, Theo Crawford, Jennifer J. Smith, Junyu Liu, Xinying Jia, Irina Vetter, Derek R. Laver, Bradley S. Launikonis, Angela Dulhunty, Eivind A. B. Undheim, Mehdi Mobli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Insect toxins with tandem repeats of neurotoxin domains have been found with enhanced receptor avidity. Here, the authors describe a bivalent toxin from remipede venom that targets ryanodine receptors, a rare target for animal venoms.
Externí odkaz:
https://doaj.org/article/ecfef30c1c5e4dc1ab651ec6f5d81576
Autor:
S. Kuschert, M. Stroet, Y. K.-Y. Chin, A. C. Conibear, X. Jia, T. Lee, C. R. O. Bartling, K. Strømgaard, P. Güntert, K. J. Rosengren, A. E. Mark, M. Mobli
Publikováno v:
Magnetic Resonance, Vol 4, Pp 57-72 (2023)
Peptides and proteins containing non-canonical amino acids (ncAAs) are a large and important class of biopolymers. They include non-ribosomally synthesised peptides, post-translationally modified proteins, expressed or synthesised proteins containing
Externí odkaz:
https://doaj.org/article/18e1d51764ce4a1196fed029911b7277
Autor:
Xiang Wang, Vitaliy V Bondar, Oliver B Davis, Michael T Maloney, Maayan Agam, Marcus Y Chin, Audrey Cheuk-Nga Ho, Rajarshi Ghosh, Dara E Leto, David Joy, Meredith EK Calvert, Joseph W Lewcock, Gilbert Di Paolo, Robert G Thorne, Zachary K Sweeney, Anastasia G Henry
Publikováno v:
eLife, Vol 12 (2023)
Leucine-rich repeat kinase 2 (LRRK2) variants associated with Parkinson’s disease (PD) and Crohn’s disease lead to increased phosphorylation of its Rab substrates. While it has been recently shown that perturbations in cellular homeostasis includ
Externí odkaz:
https://doaj.org/article/1459c4b9a28a4c35be189566695ad7a3