Zobrazeno 1 - 10
of 2 019
pro vyhledávání: '"Y. C. Tong"'
Autor:
Ouli Xie, Cameron Zachreson, Gerry Tonkin-Hill, David J. Price, Jake A. Lacey, Jacqueline M. Morris, Malcolm I. McDonald, Asha C. Bowen, Philip M. Giffard, Bart J. Currie, Jonathan R. Carapetis, Deborah C. Holt, Stephen D. Bentley, Mark R. Davies, Steven Y. C. Tong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Streptococcus dysgalactiae subspecies equisimilis (SDSE) and Streptococcus pyogenes share skin and throat niches with extensive genomic homology and horizontal gene transfer (HGT) possibly underlying shared disease phenotypes. It is unknown
Externí odkaz:
https://doaj.org/article/42a9dffb6c3c4679a54672606334ce30
Autor:
Ouli Xie, Jacqueline M. Morris, Andrew J. Hayes, Rebecca J. Towers, Magnus G. Jespersen, John A. Lees, Nouri L. Ben Zakour, Olga Berking, Sarah L. Baines, Glen P. Carter, Gerry Tonkin-Hill, Layla Schrieber, Liam McIntyre, Jake A. Lacey, Taylah B. James, Kadaba S. Sriprakash, Scott A. Beatson, Tadao Hasegawa, Phil Giffard, Andrew C. Steer, Michael R. Batzloff, Bernard W. Beall, Marcos D. Pinho, Mario Ramirez, Debra E. Bessen, Gordon Dougan, Stephen D. Bentley, Mark J. Walker, Bart J. Currie, Steven Y. C. Tong, David J. McMillan, Mark R. Davies
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human infection with invasive disease incidence and clinical manifestations comparable to the closely related species, Streptococcus pyogenes. Through systematic ge
Externí odkaz:
https://doaj.org/article/64c2683511e049649c96119d191110c7
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Bacterial species often consist of strains with variable gene content, collectively referred to as the pangenome. Variations in the genetic makeup of strains can alter bacterial physiology and fitness. To define biologically relevant genes o
Externí odkaz:
https://doaj.org/article/ccd8ca9ba7da4bce9ae862985274c7b2
Autor:
Will Cuningham, Shalinie Perera, Sonali Coulter, Zhiqiang Wang, Steven Y. C. Tong, Teresa M. Wozniak
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In northern Australia, a region with limited access to healthcare and a substantial population living remotely, antibiotic resistance adds to the complexity of treating infections. Focussing on Escherichia coli urinary tract infections (UTIs
Externí odkaz:
https://doaj.org/article/086ebf3a24e7415684e4048c2d89f9a5
Autor:
Robert K. Mahar, Anna McGlothlin, Michael Dymock, Todd C. Lee, Roger J. Lewis, Thomas Lumley, Jocelyn Mora, David J. Price, Benjamin R. Saville, Tom Snelling, Rebecca Turner, Steven A. Webb, Joshua S. Davis, Steven Y. C. Tong, Julie A. Marsh, on behalf of the SNAP Global Trial Steering Committee
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus bloodstream infection, a globally common and severe infectious disease, is trea
Externí odkaz:
https://doaj.org/article/f2f571ebfaca4b29a4b8ece1023e07d1
Autor:
Christopher Kandel, Nick Daneman, Asgar Rishu, Ranjani Somayaji, Steven Y C Tong, Jennie Johnstone, Todd C Lee, Ruxandra L Pinto, Robert A Fowler, Matthew Cheng, Emily McDonald, Joshua S Davis, Lyn Whiteway, Sean W X Ong, Robert Mahar, Lina Petrella
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Informed consent forms (ICFs) for randomised clinical trials (RCTs) can be onerous and lengthy. The process has the potential to overwhelm patients with information, leading them to miss elements of the study that are critical for an inf
Externí odkaz:
https://doaj.org/article/811777cedcf44f379b673243521c5a06
Autor:
Mark R. Davies, Nadia Keller, Stephan Brouwer, Magnus G. Jespersen, Amanda J. Cork, Andrew J. Hayes, Miranda E. Pitt, David M. P. De Oliveira, Nichaela Harbison-Price, Olivia M. Bertolla, Daniel G. Mediati, Bodie F. Curren, George Taiaroa, Jake A. Lacey, Helen V. Smith, Ning-Xia Fang, Lachlan J. M. Coin, Kerrie Stevens, Steven Y. C. Tong, Martina Sanderson-Smith, Jai J. Tree, Adam D. Irwin, Keith Grimwood, Benjamin P. Howden, Amy V. Jennison, Mark J. Walker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
A variant of group A Streptococcus serotype M1 (UK) has been increasingly reported and can be differentiated from the global variant by its overexpression of the superantigen SpeA. Here, Davies et al probe the mechanism behind enhanced SpeA expressio
Externí odkaz:
https://doaj.org/article/c8e8696ec17643b4a4f2990cdf959bbe
Autor:
Richard P. Sullivan, Jane Davies, Paula Binks, Melita McKinnon, Roslyn Gundjirryiir Dhurrkay, Kelly Hosking, Sarah Mariyalawuy Bukulatjpi, Stephen Locarnini, Margaret Littlejohn, Kathy Jackson, Steven Y. C. Tong, Joshua S. Davis
Publikováno v:
International Journal for Equity in Health, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background Chronic hepatitis B is a public health concern in Aboriginal communities in the Northern Territory of Australia with prevalence almost four times the non-Aboriginal population. Infection is suspected to mainly occur in early life,
Externí odkaz:
https://doaj.org/article/ddef7a979898407eb484c18eaa52a3d9
Autor:
Tanya J. Symons, Nicola Straiton, Rosie Gagnon, Roberta Littleford, Anita J. Campbell, Asha C. Bowen, Adam G. Stewart, Steven Y. C. Tong, Joshua S. Davis
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background For decades, the research community has called for participant information sheets/consent forms (PICFs) to be improved. Recommendations include simplifying content, reducing length, presenting information in layers and using multi
Externí odkaz:
https://doaj.org/article/46c5229c72b845daa00702e24d174d52
Autor:
M. Kalindu D. Rodrigo, Aarti Saiganesh, Andrew J. Hayes, Alisha M. Wilson, Jack Anstey, Janessa L. Pickering, Jua Iwasaki, Jessica Hillas, Scott Winslow, Tabitha Woodman, Philipp Nitschke, Jake A. Lacey, Karen J. Breese, Mark P. G. van der Linden, Philip M. Giffard, Steven Y. C. Tong, Nicola Gray, Keith A. Stubbs, Jonathan R. Carapetis, Asha C. Bowen, Mark R. Davies, Timothy C. Barnett
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
There is increasing evidence for metabolic processes mediating antimicrobial resistance. Here, the authors present a mechanism of sulfamethoxazole resistance in Group A Streptococcus that is dependent on acquiring end products of the host folate bios
Externí odkaz:
https://doaj.org/article/daae034efb764202a0ab48562b8281a1