Výsledky vyhledávání - "Y. A. Portnoy"

Akademický článek

PK/PD Modeling as a Tool for Predicting Bacterial Resistance to Antibiotics: Alternative Analyses of Experimental Data

Autor: M. V. Golikova, E. N. Strukova, Y. A. Portnoy, A. A. Firsov

Publikováno v: Антибиотики и Химиотерапия, Vol 60, Iss 9-10, Pp 12-16 (2020)

Postexposure number of mutants (NM) is a conventional endpoint in bacterial resistance studies using in vitro dynamic models that simulate antibiotic pharmacokinetics. To compare NM with a recently introduced integral parameter AUBCM, the area under

Externí odkaz: https://doaj.org/article/0db31b1cea5f47b3b22af73632991f65

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Akademický článek

Antibiotic Combinations Preventing Bacterial Resistance: Studies on an in vitro Model with Staphylococcus aureus Exposed to Linezolid–Daptomycin

Autor: K. N. Alieva, M. V. Golikova, Y. A. Portnoy, A. A. Firsov

Publikováno v: Антибиотики и Химиотерапия, Vol 64, Iss 9-10, Pp 8-13 (2020)

To predict the anti-mutant effects of antibiotic combinations against Staphylococcus aureus, the mutant prevention concentrations (MPCs) of linezolid and daptomycin were determined at a linezolid-to-daptomycin concentration ratio that corresponds to

Externí odkaz: https://doaj.org/article/4edb38e13e0f441d9b0c16dc265ed756

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Akademický článek

The scientific path of Corresponding Member of the RAS, Professor A. A. Firsop

Autor: Y. A. Portnoy, M. V. Golikova

Publikováno v: Антибиотики и Химиотерапия, Vol 65, Iss 3-4, Pp 55-56 (2020)

Externí odkaz: https://doaj.org/article/c4990c84d37142aab6979fb4a6e27759

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[PK/PD Modeling as a Tool for Predicting Bacterial Resistance to Antibiotics: Alternative Analyses of Experimental Data]

Autor: M V, Golikova, E N, Strukova, Y A, Portnoy, A A, Firsov

Publikováno v: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 60(9-10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab44a69956e12e6ecf538e4bfd17bcdc
https://pubmed.ncbi.nlm.nih.gov/27141633

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Simulated in vitro quinolone pharmacodynamics at clinically achievable AUC/MIC ratios: advantage of I E over other integral parameters

Autor: A A, Firsov, S H, Zinner, I Y, Lubenko, Y A, Portnoy, S N, Vostrov

Publikováno v: Chemotherapy. 48(6)

To compare the antimicrobial effects of clinically achievable ratios of area under the curve (AUC) to MIC, a clinical isolate of Moraxella catarrhalis was selected with MICs corresponding to the MIC(50)s of four quinolones. Monoexponentially declinin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98a272bb1485016c04bdb0e92b41f518
https://pubmed.ncbi.nlm.nih.gov/12673102

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