Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

Autor: Pekka Ellonen, Ekaterina Riabchenko, David C. Wedge, Y. A. Golubeva, Daniel Brewer, Matti Kankainen, Michael R. Emmert-Buck, Tapio Visakorpi, A. C. Warner, Maija Lepistö, J. Jasu, G. S. Bova, Dan J. Woodcock, Teemu Tolonen, William B. Isaacs, Matti Nykter, Sinja Taavitsainen, Gunes Gundem

Publikováno v: Woodcock, D J, Riabchenko, E, Taavitsainen, S, Kankainen, M, Gundem, G, Brewer, D S, Ellonen, P, Lepistö, M, Golubeva, Y A, Warner, A C, Tolonen, T, Jasu, J, Isaacs, W B, Emmert-buck, M R, Nykter, M, Visakorpi, T, Bova, G S & Wedge, D C 2020, ' Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-18843-5
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications

The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. We infer detailed reconstructions of tumor phylogenies in ten prostate cancer patients with fatal dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6788ffdd1cdb193b40d7588db221f973
http://www.nature.com/articles/s41467-020-18843-5