Erratum: A gene expression signature for high-risk multiple myeloma

Autor: E H van Beers, Annemiek Broyl, M. van Vliet, Y de Knegt, M. van Duin, Rowan Kuiper, G Morgan, H. M. Lokhorst, B. van der Holt, Pieter Sonneveld, W Gregory, George Mulligan, H. Goldschmidt, L el Jarari

Publikováno v: Leukemia. 28:1178-1180

Correction to: Leukemia (2012) 26, 2406–2413; doi:10.1038/leu.2012.127 Since the publication of this article, the authors have discovered an error in the script for calculating the IFM-15 risk scores. In their paper, they described the weights of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c8de70f8f0b1f25757c47f333f18290
https://doi.org/10.1038/leu.2014.53

MicroRNA signatures characterize multiple myeloma patients

Autor: Justine K. Peeters, Pieter Sonneveld, H B Beverloo, Su Ming Sun, Sonja Zweegman, H. M. Lokhorst, Rowan Kuiper, Sophie L. Corthals, Y. de Knegt, L el Jarari, Mojca Jongen-Lavrencic, Annemiek Broyl, B. van der Holt

Publikováno v: Corthals, S L, Sun, S M, Kuiper, R, de Knegt, Y, Broyl, A, van der Holt, B, Beverloo, HB, Peeters, J K, el Jarari, L, Lokhorst, H M, Zweegman, S, Jongen-Lavrencic, M & Sonneveld, P 2011, ' MicroRNA signatures characterize multiple myeloma patients ', Leukemia, vol. 25, no. 11, pp. 1784-1789 . https://doi.org/10.1038/leu.2011.147
Leukemia, 25(11), 1784-1789. Nature Publishing Group

MicroRNAs (miRNAs) are a class of small non-coding single-stranded RNAs of ~22 nucleotides in length that regulate protein levels by binding to either partially or complete complementary sites in messenger RNAs (mRNAs), leading to translational repre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c51b542e8888147508915cc490baf6
https://pubmed.ncbi.nlm.nih.gov/21701488

Gene Expression Profiles for Molecular Classification of Multiple Myeloma in Newly Diagnosed Patients Included in a Prospective, Multicenter, Phase 3 Trial

Autor: Pieter Sonneveld, Justine K. Peeters, H. Goldschmidt, B Beverloo, Y. de Knegt, M. van Duin, Annemiek Broyl, Dirk Hose, H. M. Lokhorst

Publikováno v: Blood. 112:1683-1683

Multiple Myeloma (MM) is characterized by the presence of a monoclonal protein, immunodeficiency, anemia, renal failure and bone lesions. New agents like Bortezomib (Bor) and Thalidomide (Thal) have shown efficacy in 40% of patients with relapsed/ref

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d472fc7b689e0ae59ade7e9155622ff
https://doi.org/10.1182/blood.v112.11.1683.1683

Influence of Genetic Single Nucleotide Polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 Genes on Survival and Treatment Related Toxicity in Patients with Multiple Myeloma Treated in the HOVON 24 Trial

Autor: Edo Vellenga, Eric Kamst, R. Raymakers, Y. de Knegt, Henk M. Lokhorst, C Schilthuizen, B. van der Holt, Pieter Sonneveld

Publikováno v: Blood. 106:505-505

Cytochromes P450 (CYP 450) and gluthatione-S-transferases (GSTs) are drug metabolizing enzymes involved in the detoxification of numerous chemotherapeutic agents.The Multidrug Resistance gene 1 (MDR1, ABCB1) is a transmembrane drug transporter presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc24867cc1c24e149c0d68571d0701f9
https://doi.org/10.1182/blood.v106.11.505.505

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