Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Y U Sun"'
Publikováno v:
Anticancer Research. 41:1213-1218
Background/aim Overexpression of inflammatory cytokines and oxidative stress increase the risk of colorectal cancer (CRC) in obesity and hyperlipidemia. The aim of this study was to investigate whether the monoterpene antioxidant p-cymene would reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a627a6126a191cf9cb15ed92195d9d47
https://doi.org/10.21873/anticanres.14878
https://doi.org/10.21873/anticanres.14878
Autor:
Y U Sun, Wei Xu, Min Li, Wei-Wei Song, Robert M. Hoffman, Mingjiong Zhang, Qiqing Huang, Jianqing Wu, Yumin Zan, Yuzhuo Wang, Weihong Zhao
Publikováno v:
Cancer Genomics Proteomics
Background/aim The prevalence of idiopathic pulmonary fibrosis (IPF) increases with age and is associated with senescence of alveolar epithelial cells (AECs). AEC senescence in pulmonary cells mediates IPF. We herein aimed to determine if YAP1 gene k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32196dbb734daa99bc396f4e7e219d74
https://doi.org/10.21873/cgp.20271
https://doi.org/10.21873/cgp.20271
Autor:
Jia Meng, Qiangqiang Chu, Wenhong Dong, Haitao Yang, Yingying Du, Robert M. Hoffman, Y U Sun, Song Peng
Publikováno v:
In Vivo
Background/aim Small-cell lung cancer (SCLC) is a recalcitrant disease with liver and other metastasis. The present study evaluated the efficacy of the traditional Chinese medicine Brucea javanica oil (BJO) combined with anlotinib, a multi-tyrosine k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a795115af8b7772bff7dcac32cc5979
https://doi.org/10.21873/invivo.12395
https://doi.org/10.21873/invivo.12395
Autor:
Kazuyuki Hamada, Y U Sun, Robert M. Hoffman, Norihiko Sugisawa, Guangwei Zhu, Jun Yamamoto, Hye In Lim, Hiroto Nishino
Publikováno v:
Anticancer Research. 40:6083-6091
Background/aim The aim of the study was to determine if oral recombinant methioninase (o-rMETase) can sensitize an orthotopic bladder tumor in nude mice to low-dose cisplatinum (CDDP). Materials and methods The green fluorescent protein (GFP)-express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d170b2edf9ce2a38afdd094844470ecb
https://doi.org/10.21873/anticanres.14629
https://doi.org/10.21873/anticanres.14629
Publikováno v:
Anticancer Research. 40:4969-4978
BACKGROUND/AIM Traditional Chinese medicine (TCM) Brucea javanica (BJO) has shown anti-proliferation efficacy on human carcinoma cells in vitro. The aim of the present study was to evaluate for the first time the efficacy of BJO combined with the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::232a3114690110d877372558518b1f7a
https://doi.org/10.21873/anticanres.14500
https://doi.org/10.21873/anticanres.14500
Autor:
Seok Jin Nam, Michael Bouvet, Chihiro Hozumi, Ji Sun Lee, Y U Sun, Quinhong Han, Moon Bo Kim, Hye In Lim, Norihiko Sugisawa, Hee Jun Choi, Shree Ram Singh, Hiroto Nishino, Robert M. Hoffman, Jun Yamamoto, Sachiko Inubushi, Yoshihiko Tashiro
Publikováno v:
Anticancer Research. 40:2481-2485
BACKGROUND/AIM In the present study, the breast cancer patient-derived orthotopic xenograft (PDOX) model was used to identify an effective drug for a highly aggressive triple negative breast cancer (TNBC). MATERIALS AND METHODS The TNBC tumor from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a842eefaf86edc05e7cc9b4c262d7ad
https://doi.org/10.21873/anticanres.14218
https://doi.org/10.21873/anticanres.14218
Autor:
Itaru Endo, Kentaro Miyake, Chihiro Hozumi, Jun Yamamoto, Koichiro Shimoya, Robert M. Hoffman, Junichi Kurebayashi, Tsunehisa Nomura, Norihiko Sugisawa, Takashi Higuchi, Sachiko Inubushi, Takuya Murata, Hyein Lim, Shree Ram Singh, Hirokazu Tanino, Y U Sun, Hiroto Nishino, Yoshihiko Tashiro, Michael Bouvet
Publikováno v:
Anticancer Research. 40:2475-2479
Background/aim Matrix-producing breast carcinoma (MPBC) is a rare and usually aggressive triple-negative breast cancer (TNBC). In the present report, we determined the drug sensitivity for a triple-negative MPBC using a patient-derived orthotopic xen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007c63c797b9544a125dcf075c477fe7
https://doi.org/10.21873/anticanres.14217
https://doi.org/10.21873/anticanres.14217
Autor:
Y U Sun, Robert M. Hoffman, Qinghong Han, Shree Ram Singh, Michael Bouvet, Yuying Tan, Guangwei Zhu, Jianxin Ye, Ming Zhao
Publikováno v:
Cancer genomics & proteomics, vol 17, iss 2
Background/Aim: Pazopanib (PAZ) can inhibit tumor progression, but whether PAZ inhibits lymph node metastasis and lymphangiogenesis in colorectal cancer is still unknown. The aim of the present study was to determine the efficacy of PAZ on tumor grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338671d9595d80f3260cbd02ea328427
https://doi.org/10.21873/cgp.20173
https://doi.org/10.21873/cgp.20173
Autor:
Michael Bouvet, Yoshihisa Takahashi, Qinghong Han, Yoshihiko Tashiro, Hiroto Nishino, Robert M. Hoffman, Norihiko Sugisawa, Masahiko Murakami, Y U Sun, Sachiko Inubushi, Takeshi Aoki, Jun Yamamoto, Hyein Lim, Yuying Tan
Publikováno v:
In Vivo
Background/aim We have recently shown that oral recombinant methionase (o-rMETase) prevents obesity and diabetes onset in mice on a high-fat (HF) diet. The present study aimed to determine if o-rMETase can inhibit the onset of nonalcoholic fatty live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a0f47cdfee0352b948bd8ecc3580f7
https://doi.org/10.21873/invivo.11866
https://doi.org/10.21873/invivo.11866
Autor:
Hannah M. Hollandsworth, Hiroto Nishino, Robert M. Hoffman, Jun Yamamoto, Siamak Amirfakhri, Y U Sun, Filemoni Filemoni, Hyein Lim, Michael Bouvet, Kazuyuki Hamada, Norihiko Sugisawa, Yoshihiko Tashiro, Sachiko Inubushi
Publikováno v:
In Vivo
Background/Aim: Surgical orthotopic implantation (SOI) is used to establish patient-derived orthotopic xenograft (PDOX) and other orthotopic mouse models. Orthotopic liver models can be challenging, as the liver parenchyma is prone to bleeding. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da5570d093c01de3e8e4cf034581548
https://doi.org/10.21873/invivo.12149
https://doi.org/10.21873/invivo.12149