Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Y Terry Lee"'
Autor:
Benjamin A Clarke, Saurav Majumder, Hongling Zhu, Y Terry Lee, Mari Kono, Cuiling Li, Caroline Khanna, Hailey Blain, Ronit Schwartz, Vienna L Huso, Colleen Byrnes, Galina Tuymetova, Teresa M Dunn, Maria L Allende, Richard L Proia
Publikováno v:
eLife, Vol 8 (2019)
Sphingolipids are membrane and bioactive lipids that are required for many aspects of normal mammalian development and physiology. However, the importance of the regulatory mechanisms that control sphingolipid levels in these processes is not well un
Externí odkaz:
https://doaj.org/article/2c0b70daaf154f68988f8dd68ab972c9
Autor:
Jaira F de Vasconcellos, Y Terry Lee, Colleen Byrnes, Laxminath Tumburu, Antoinette Rabel, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166928 (2016)
Induction of fetal hemoglobin (HbF) has therapeutic importance for patients with beta-hemoglobin disorders. Previous studies showed that let-7 microRNAs (miRNAs) are highly regulated in erythroid cells during the fetal-to-adult developmental transiti
Externí odkaz:
https://doaj.org/article/6e85be65ef8c40d79322ed64756c05fa
Autor:
Y Terry Lee, Jaira F de Vasconcellos, Colleen Byrnes, Megha Kaushal, Antoinette Rabel, Laxminath Tumburu, Joshua M Allwardt, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144977 (2015)
Increasing fetal hemoglobin (HbF) levels in adult humans remains an active area in hematologic research. Here we explored erythroid-specific LIN28A expression for its effect in regulating gamma-globin gene expression and HbF levels in cultured adult
Externí odkaz:
https://doaj.org/article/1ed0f547493d4b89b40c0aed8de8c73d
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136672 (2015)
Hemoglobin switching is largely complete in humans by six months of age. Among infants with sickle cell anemia (HbSS, SCA), reticulocytosis begins early in life as fetal hemoglobin (HbF) is replaced by sickle hemoglobin (HbS). The objective of this s
Externí odkaz:
https://doaj.org/article/7dba86333b9f45f78d5f13eaa5219161
Autor:
Jaira F de Vasconcellos, Ross M Fasano, Y Terry Lee, Megha Kaushal, Colleen Byrnes, Emily R Meier, Molly Anderson, Antoinette Rabel, Raul Braylan, David F Stroncek, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106924 (2014)
Induction of fetal hemoglobin (HbF) has therapeutic importance for patients with sickle cell disease (SCD) and the beta-thalassemias. It was recently reported that increased expression of LIN28 proteins or decreased expression of its target let-7 miR
Externí odkaz:
https://doaj.org/article/9bd86e2bf17b49fa974c4e74c512585d
Autor:
Emily Riehm Meier, Colleen Byrnes, Y Terry Lee, Elizabeth C Wright, Alan N Schechter, Naomi L C Luban, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70794 (2013)
OBJECTIVE: Among older children with sickle cell anemia, leukocyte counts, hemoglobin, and reticulocytosis have previously been suggested as disease severity markers. Here we explored whether these blood parameters may be useful to predict early chil
Externí odkaz:
https://doaj.org/article/dcebfe1e4ccc463fac9ee8504477267a
Autor:
Y Terry Lee, Ki Soon Kim, Colleen Byrnes, Jaira F de Vasconcellos, Seung-Jae Noh, Antoinette Rabel, Emily R Meier, Jeffery L Miller
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68307 (2013)
Based upon the lack of clinical samples available for research in many laboratories worldwide, a significant gap exists between basic and clinical studies of beta-thalassemia major. To bridge this gap, we developed an artificially engineered model fo
Externí odkaz:
https://doaj.org/article/c1809207b7d04fab9fa1e8ee7c328115
Autor:
Maria L. Allende, Y. Terry Lee, Colleen Byrnes, Cuiling Li, Galina Tuymetova, Jenna Y. Bakir, Elena-Raluca Nicoli, Virginia K. James, Jennifer S. Brodbelt, Cynthia J. Tifft, Richard L. Proia
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 12, Pp 100463- (2023)
GM1 gangliosidosis is a neurodegenerative disorder caused by mutations in the GLB1 gene, which encodes lysosomal β-galactosidase. The enzyme deficiency blocks GM1 ganglioside catabolism, leading to accumulation of GM1 ganglioside and asialo-GM1 gang
Externí odkaz:
https://doaj.org/article/94f9b0fdff3447668849eed7667b5c00
Autor:
Hongling Zhu, Colleen Byrnes, Y. Terry Lee, Galina Tuymetova, Hannah B. D. Duffy, Jenna Y. Bakir, Sydney N. Pettit, Jabili Angina, Danielle A. Springer, Maria L. Allende, Mari Kono, Richard L. Proia
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797093d181d269bacc98874fcb863aeb
https://doi.org/10.1096/fj.202300149r
https://doi.org/10.1096/fj.202300149r
Autor:
Mari Kono, Y. Terry Lee, Cuiling Li, Richard L. Proia, Colleen Byrnes, Galina Tuymetova, Saurav Majumder
Publikováno v:
The Journal of Biological Chemistry
Sphingolipid biosynthesis generates lipids for membranes and signaling that are crucial for many developmental and physiological processes. In some cases, large amounts of specific sphingolipids must be synthesized for specialized physiological funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1004fbe13989c817ef29b49464a1a842
https://doi.org/10.1074/jbc.ac119.011170
https://doi.org/10.1074/jbc.ac119.011170