Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Y Sanchez Gonzalez"'
Autor:
G D'Haens, J Tran, S Danese, D T Rubin, N Aoyama, A Lügering, J Klaff, S Xuan, D Ilo, Y Sanchez Gonzalez, J Panes
Publikováno v:
Journal of Crohn's and Colitis. 17:i27-i29
Background Abdominal pain (AP), bowel urgency (BU), stool frequency (SF), rectal bleeding (RB) and fatigue are debilitating symptoms that reduce quality of life in patients with ulcerative colitis (UC). Results from two Phase 3 induction trials and o
Autor:
K V Patel, P Salmon, I Marin-Jiménez, M Thessen, K Kligys, D Sharma, Y Sanchez Gonzalez, J Kershaw
Publikováno v:
Journal of Crohn's and Colitis. 17:i544-i546
Background Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) with increasing healthcare resource utilisation (HCRU) and associated costs. Optimal management of CD and UC aims to induce and maintain remis
Akademický článek
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Akademický článek
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Autor:
R Panaccione, E B Collins, G Y Melmed, S Vermeire, S Danese, P D R Higgins, W Zhou, D Ilo, D Sharma, Y Sanchez Gonzalez, S T Wang
Publikováno v:
Journal of Crohn's and Colitis. 16:i037-i041
Background The therapeutic armamentarium to treat adult patients with moderately to severely active ulcerative colitis (UC) continues to evolve. With this rapid innovation, the comparative efficacy and safety of more recent advanced therapies remain
Autor:
W Reinisch, J Tran, K Patel, N Borruel, G Y Melmed, L Wegrzyn, G Levy, D Ilo, Y Sanchez Gonzalez, R Panaccione
Publikováno v:
Journal of Crohn's and Colitis. 17:i785-i786
Background Upadacitinib (UPA) and tofacitinib (TOFA) are Janus kinase (JAK) inhibitors approved for the treatment of patients (pts) with moderately to severely active ulcerative colitis (UC), but evidence on their comparative efficacy and safety is l
Autor:
I Blumenstein, S Xuan, R Panaccione, F Baert, M Barreiro-de Acosta, B D Ye, J Klaff, R Vladea, G Levy, C T J Holweg, Y Sanchez Gonzalez, M C Dubinsky
Publikováno v:
Journal of Crohn's and Colitis. 17:i333-i334
Background Upadacitinib (UPA) demonstrated efficacy and safety as induction and maintenance therapy for ulcerative colitis (UC) in Phase 3 trials U-ACHIEVE (NCT02819635) and U-ACCOMPLISH (NCT03653026). This post-hoc analysis aims to characterise the
Autor:
W Reinisch, R Panaccione, M Duijvestein, D Ceballos Santos, G Y Melmed, S Xuan, L Wegrzyn, G Levy, D Ilo, Y Sanchez Gonzalez
Publikováno v:
Journal of Crohn's and Colitis. 17:i672-i673
Background Upadacitinib (UPA), an oral Janus kinase inhibitor, and ustekinumab (UST), a parenteral IL-12/23 inhibitor, are approved therapies for patients (pts) with moderately to severely active Ulcerative Colitis (UC). In the absence of head-to-hea
Autor:
Wen Zhou, M A Weinreich, Silvio Danese, Severine Vermeire, Aileen L. Pangan, Hiroshi Nakase, R Pannaccione, Peter D.R. Higgins, Bidan Huang, Xavier Hébuterne, Y Sanchez-Gonzalez, M H Chen, Wangang Xie, Jesse S. Siffledeen, J Liu
Publikováno v:
Journal of Crohn's & Colitis
Background An unmet therapeutic need remains in patients with ulcerative colitis (UC). U-ACHIEVE is one of two phase 3 induction trials evaluating the safety and efficacy of the selective Janus kinase–1 inhibitor upadacitinib (UPA) 45 mg once daily
Autor:
R Panaccione, S Danese, W Zhouwen, A Pangan, X Hébuterne, H Nakase, G D’Haens, J Panes, J Lindsay, P Higgins, E Loftus, W Sandborn, W Xie, Y Sanchez gonzalez, J Liu, M Weinreich, S Vermeire
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 5:18-19
Background Upadacitinib (UPA), an oral selective and reversible JAK inhibitor, demonstrated significantly greater efficacy compared with placebo (PBO) for induction of remission in patients with moderately to severely active ulcerative colitis (UC) i