Výsledky vyhledávání - "Y Sanchez Gonzalez"

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OP20 The effects of upadacitinib on ulcerative colitis symptom resolution and fatigue normalization in patients with moderately to severely active ulcerative colitis: Phase 3 U-ACHIEVE and U-ACCOMPLISH results

Autor: G D'Haens, J Tran, S Danese, D T Rubin, N Aoyama, A Lügering, J Klaff, S Xuan, D Ilo, Y Sanchez Gonzalez, J Panes

Publikováno v: Journal of Crohn's and Colitis. 17:i27-i29

Background Abdominal pain (AP), bowel urgency (BU), stool frequency (SF), rectal bleeding (RB) and fatigue are debilitating symptoms that reduce quality of life in patients with ulcerative colitis (UC). Results from two Phase 3 induction trials and o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26ea7a0f84780ca2fea3ae29f95e9d30
https://doi.org/10.1093/ecco-jcc/jjac190.0020

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P416 The impact of remission on healthcare resource utilisation and costs amongst patients with inflammatory bowel disease in France, Germany, Italy, Spain, and the United Kingdom

Autor: K V Patel, P Salmon, I Marin-Jiménez, M Thessen, K Kligys, D Sharma, Y Sanchez Gonzalez, J Kershaw

Publikováno v: Journal of Crohn's and Colitis. 17:i544-i546

Background Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) with increasing healthcare resource utilisation (HCRU) and associated costs. Optimal management of CD and UC aims to induce and maintain remis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9787fd56d5e5b1fcdaf469e6ba196e39
https://doi.org/10.1093/ecco-jcc/jjac190.0546

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Akademický článek

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K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

OP34 Efficacy and safety of advanced induction and maintenance therapies in patients with moderately to severely active Ulcerative Colitis: An indirect treatment comparison using Bayesian network meta-analysis

Autor: R Panaccione, E B Collins, G Y Melmed, S Vermeire, S Danese, P D R Higgins, W Zhou, D Ilo, D Sharma, Y Sanchez Gonzalez, S T Wang

Publikováno v: Journal of Crohn's and Colitis. 16:i037-i041

Background The therapeutic armamentarium to treat adult patients with moderately to severely active ulcerative colitis (UC) continues to evolve. With this rapid innovation, the comparative efficacy and safety of more recent advanced therapies remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eda110baec24c7872aba18d88394db97
https://doi.org/10.1093/ecco-jcc/jjab232.033

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P658 Comparative Efficacy and Safety of Upadacitinib Versus Tofacitinib as Induction Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: A Matching-Adjusted Indirect Comparison

Autor: W Reinisch, J Tran, K Patel, N Borruel, G Y Melmed, L Wegrzyn, G Levy, D Ilo, Y Sanchez Gonzalez, R Panaccione

Publikováno v: Journal of Crohn's and Colitis. 17:i785-i786

Background Upadacitinib (UPA) and tofacitinib (TOFA) are Janus kinase (JAK) inhibitors approved for the treatment of patients (pts) with moderately to severely active ulcerative colitis (UC), but evidence on their comparative efficacy and safety is l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ae3cf04d1a0209d70c7f92cae64d7cd
https://doi.org/10.1093/ecco-jcc/jjac190.0788

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P179 Comparative benefit-risk profile of induction and maintenance therapy with upadacitinib versus placebo in patients with moderately to severely active ulcerative colitis

Autor: I Blumenstein, S Xuan, R Panaccione, F Baert, M Barreiro-de Acosta, B D Ye, J Klaff, R Vladea, G Levy, C T J Holweg, Y Sanchez Gonzalez, M C Dubinsky

Publikováno v: Journal of Crohn's and Colitis. 17:i333-i334

Background Upadacitinib (UPA) demonstrated efficacy and safety as induction and maintenance therapy for ulcerative colitis (UC) in Phase 3 trials U-ACHIEVE (NCT02819635) and U-ACCOMPLISH (NCT03653026). This post-hoc analysis aims to characterise the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3687a83b9835d7eebd3c1ed419864e88
https://doi.org/10.1093/ecco-jcc/jjac190.0309

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P546 Comparative efficacy and safety of upadacitinib versus ustekinumab as induction therapy in patients with moderately to severely active ulcerative colitis: A matching-adjusted indirect comparison

Autor: W Reinisch, R Panaccione, M Duijvestein, D Ceballos Santos, G Y Melmed, S Xuan, L Wegrzyn, G Levy, D Ilo, Y Sanchez Gonzalez

Publikováno v: Journal of Crohn's and Colitis. 17:i672-i673

Background Upadacitinib (UPA), an oral Janus kinase inhibitor, and ustekinumab (UST), a parenteral IL-12/23 inhibitor, are approved therapies for patients (pts) with moderately to severely active Ulcerative Colitis (UC). In the absence of head-to-hea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d21830a14a831c3ea0805788ddbadb0a
https://doi.org/10.1093/ecco-jcc/jjac190.0676

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OP24 Efficacy and safety of upadacitinib induction therapy in patients with Moderately to Severely Active Ulcerative Colitis: Results from the phase 3 U-ACHIEVE study

Autor: Wen Zhou, M A Weinreich, Silvio Danese, Severine Vermeire, Aileen L. Pangan, Hiroshi Nakase, R Pannaccione, Peter D.R. Higgins, Bidan Huang, Xavier Hébuterne, Y Sanchez-Gonzalez, M H Chen, Wangang Xie, Jesse S. Siffledeen, J Liu

Publikováno v: Journal of Crohn's & Colitis

Background An unmet therapeutic need remains in patients with ulcerative colitis (UC). U-ACHIEVE is one of two phase 3 induction trials evaluating the safety and efficacy of the selective Janus kinase–1 inhibitor upadacitinib (UPA) 45 mg once daily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1e313c4b142af5c947df4d3a77994b
https://doi.org/10.1093/ecco-jcc/jjab075.023

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