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Peripheral V gamma 9/V delta 2 T cell deletion and anergy to nonpeptidic mycobacterial antigens in asymptomatic HIV-1-infected persons

Autor: F Poccia, S Boullier, H Lecoeur, M Cochet, Y Poquet, V Colizzi, J J Fournie, M L Gougeon

Publikováno v: The Journal of Immunology. 157:449-461

Gamma delta T cells represent a minor population of human peripheral lymphocytes, the majority of them expressing the V delta 2/V gamma 9 TCR. Their accumulation in infectious disease lesions and their reactivity toward mycobacterial Ags suggest that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09d215dabd2f3401a003b80496dac9e6
https://doi.org/10.4049/jimmunol.157.1.449

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Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands

Autor: F Lang, M A Peyrat, P Constant, F Davodeau, J David-Ameline, Y Poquet, H Vié, J J Fournié, M Bonneville

Publikováno v: The Journal of Immunology. 154:5986-5994

Human V gamma 9V delta 2 T cells were shown recently to respond to nonpeptidic phosphorylated molecules of mycobacterial origin (previously referred to as TUBag). To investigate the early events of V gamma 9V delta 2 T cell activation, we have analyz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::168501d4e8d3d92638c28ebba97df761
https://doi.org/10.4049/jimmunol.154.11.5986

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Akademický článek

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Regulation by cytokines (IL-12, IL-15, IL-4 and IL-10) of the Vgamma9Vdelta2 T cell response to mycobacterial phosphoantigens in responder and anergic HIV-infected persons

Autor: S, Boullier, Y, Poquet, T, Debord, J J, Fournie, M L, Gougeon

Publikováno v: European journal of immunology. 29(1)

Human Vgamma9Vdelta2 T cells contribute to immunity against intracellular pathogens and recognize nonpeptidic antigens, such as the mycobacterial phosphoantigen TUBAg. HIV infection is associated with a polyclonal decrease of peripheral Vgamma9Vdelta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c96be95dccff6b3357cc57a5ced8924
https://pubmed.ncbi.nlm.nih.gov/9933090

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Phosphoantigen activation induces surface translocation of intracellular CD94/NKG2A class I receptor on CD94- peripheral Vgamma9 Vdelta2 T cells but not on CD94- thymic or mature gammadelta T cell clones

Autor: S, Boullier, Y, Poquet, F, Halary, M, Bonneville, J J, Fournie, M L, Gougeon

Publikováno v: European journal of immunology. 28(11)

Most adult peripheral blood gammadelta T cells express Vgamma9/Vdelta2-encoded TCR that recognize a restricted set of nonpeptidic phosphorylated compounds, referred to as phosphoantigens. They also express various MHC class I-specific inhibitory rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9623fee121c066591c1366133f84fb4b
https://pubmed.ncbi.nlm.nih.gov/9842883

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Akademický článek

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Human gamma delta T cells in tuberculosis

Autor: Y, Poquet, F, Halary, E, Champagne, F, Davodeau, M L, Gougeon, M, Bonneville, J J, Fournié

Publikováno v: Research in immunology. 147(8-9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3dbbadd689ace6e98fdedaf7b97db1dd
https://pubmed.ncbi.nlm.nih.gov/9127886

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Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands

Autor: P, Constant, F, Davodeau, M A, Peyrat, Y, Poquet, G, Puzo, M, Bonneville, J J, Fournié

Publikováno v: Science (New York, N.Y.). 264(5156)

Most human peripheral blood gamma delta T lymphocytes respond to hitherto unidentified mycobacterial antigens. Four ligands from Mycobacterium tuberculosis strain H37Rv that stimulated proliferation of a major human gamma delta T cell subset were iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b905118d236a9fc978027edae7a445fa
https://pubmed.ncbi.nlm.nih.gov/8146660

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