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A class I MHC-restricted recall response to a viral peptide is highly polyclonal despite stringent CDR3 selection: implications for establishing memory T cell repertoires in 'real-world' conditions

Autor: Y N, Naumov, K T, Hogan, E N, Naumova, J T, Pagel, J, Gorski

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 160(6)

In this study, we analyze the recall response to influenza A matrix peptide M1(58-66) restricted by HLA-A2 in one individual and find a strict CDR3 selection as well as a high degree of polyclonality. The TCR beta-chain repertoire of memory T cells s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c6ab6f33332fa2d8dd9b12e6a1fc3ee
https://pubmed.ncbi.nlm.nih.gov/9510187

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