Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Y M Mowery"'
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0225019 (2020)
Small animal imaging has become essential in evaluating new cancer therapies as they are translated from the preclinical to clinical domain. However, preclinical imaging faces unique challenges that emphasize the gap between mouse and man. One exampl
Externí odkaz:
https://doaj.org/article/a573d7d261724b138d2614cc13972f7e
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0207555 (2019)
In designing co-clinical cancer studies, preclinical imaging brings unique challenges that emphasize the gap between man and mouse. Our group is developing quantitative imaging methods for the preclinical arm of a co-clinical trial studying immunothe
Externí odkaz:
https://doaj.org/article/8703e6cdaa184793bfa7737bb22a7da5
Publikováno v:
Journal of cellular biochemistry. 112(6)
Receptor-recognized forms of α₂ -macroglobulin (α₂ M) bind to cell surface-associated GRP78 and initiate pro-proliferative and anti-apoptotic signaling. Ligation of GRP78 with α₂ M also upregulates TFII-I, which binds to the GRP78 promoter a