Výsledky vyhledávání - "Y M, Newhouse"

Human apolipoprotein E7:lysine mutations in the carboxy-terminal domain are directly responsible for preferential binding to very low density lipoproteins

Autor: J, Dong, M E, Balestra, Y M, Newhouse, K H, Weisgraber

Publikováno v: Journal of lipid research. 41(11)

Apolipoprotein E7 (apoE7) (apoE3 E244K/E245K) is a naturally occurring mutant in humans that is associated with increased plasma lipid levels and accelerated atherosclerosis. It is reported to display defective binding to low density lipoprotein (LDL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff110e803eec1e722179a0febbf2b204
https://pubmed.ncbi.nlm.nih.gov/11060347

Zobrazit plný text záznamu

The carboxyl terminus in apolipoprotein E2 and the seven amino acid repeat in apolipoprotein E-Leiden: role in receptor-binding activity

Autor: L M, Dong, T L, Innerarity, K S, Arnold, Y M, Newhouse, K H, Weisgraber

Publikováno v: Journal of lipid research. 39(6)

Both apolipoprotein (apo) E2 and apoE-Leiden (tandem repeat of amino acids 121-127) are associated with type III hyperlipoproteinemia and bind defectively to low density lipoprotein receptors. Removing the carboxyl terminus of both variants (residues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d29fabc3ccb68c2d4a5252c6c2acc628
https://pubmed.ncbi.nlm.nih.gov/9643348

Zobrazit plný text záznamu

Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coli

Autor: T, Simmons, Y M, Newhouse, K S, Arnold, T L, Innerarity, K H, Weisgraber

Publikováno v: The Journal of biological chemistry. 272(41)

The low density lipoprotein (LDL) receptor plays a key role in cholesterol homeostasis, mediating cellular uptake of lipoprotein particles by high affinity binding to its ligands, apolipoprotein (apo) B-100 and apoE. The ligand-binding domain of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c2982f7f02d99df06eedbe7294fc709
https://pubmed.ncbi.nlm.nih.gov/9325268

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání