Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Y M, Deo"'
Publikováno v:
The Journal of Immunology. 158:872-879
A bispecific fusion protein (H22-EGF) that binds simultaneously to the epidermal growth factor receptor (EGF-R) and to the high affinity receptor for the Fc portion of human IgG, Fc gammaRI (CD64), has been successfully constructed and expressed. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468370b88fe66289908ec4f80f6c343f
https://doi.org/10.4049/jimmunol.158.2.872
https://doi.org/10.4049/jimmunol.158.2.872
Publikováno v:
Blood. 94(6)
Cross-linking of Fc receptors for IgA, FcalphaR (CD89), on monocytes/macrophages is known to enhance phagocytic activity and generation of oxygen free radicals. We provide evidence here that the FcalphaR signals through the gamma subunit of Fcepsilon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1afeb8578df45b95f5a4d3778dd868e3
https://pubmed.ncbi.nlm.nih.gov/10477741
https://pubmed.ncbi.nlm.nih.gov/10477741
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(9)
A bispecific antibody was made by chemical conjugation of Fab' fragments from humanized antibodies specific for tumor-associated glycoprotein-72 (TAG-72) and high-affinity immunoglobulin receptor, FcgammaA receptor type I (FcgammaRI). The purified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b89a166f49ef42af0d733ab0eb1712b1
https://pubmed.ncbi.nlm.nih.gov/9748144
https://pubmed.ncbi.nlm.nih.gov/9748144
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(4)
The FcR for IgA (Fc alpha RI, CD89) is primarily expressed on cytotoxic immune effector cells. By chemically cross-linking F(ab') fragments of the FcR for IgA (Fc alpha RI)-specific mAb (A77) with tumor Ag-specific mAb (anti-HER2/neu and anti-epiderm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47bc67567ca05609808173b7abbb5d60
https://pubmed.ncbi.nlm.nih.gov/9469424
https://pubmed.ncbi.nlm.nih.gov/9469424
Autor:
T, Valerius, B, Stockmeyer, A B, van Spriel, R F, Graziano, I E, van den Herik-Oudijk, R, Repp, Y M, Deo, J, Lund, J R, Kalden, M, Gramatzki, J G, van de Winkel
Publikováno v:
Blood. 90(11)
Promising results from clinical trials with unconjugated antibodies stimulated renewed interest in immune effector mechanisms of monoclonal antibodies (MoAbs). We investigated the potential of IgA as antibody isotype for cell- or complement-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::720b369f5b8521a8a7692f3993e29236
https://pubmed.ncbi.nlm.nih.gov/9373259
https://pubmed.ncbi.nlm.nih.gov/9373259
Autor:
T, Keler, R F, Graziano, A, Mandal, P K, Wallace, J, Fisher, P M, Guyre, M W, Fanger, Y M, Deo
Publikováno v:
Cancer research. 57(18)
A bispecific antibody, MDX-H210, was developed to target cytotoxic effector cells expressing Fc gamma receptor type I (Fc gammaRI, CD64) to HER2/neu-overexpressing tumor cells. HER2/neu is an appropriate target for immunotherapy due to the high level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fd2456b7bda5458ca4b34c59ea5a049
https://pubmed.ncbi.nlm.nih.gov/9307286
https://pubmed.ncbi.nlm.nih.gov/9307286
Autor:
B, Stockmeyer, T, Valerius, R, Repp, I A, Heijnen, H J, Bühring, Y M, Deo, J R, Kalden, M, Gramatzki, J G, van de Winkel
Publikováno v:
Cancer research. 57(4)
Immunotherapies directed to the proto-oncogene product HER-2/neu, which is overexpressed on a subset of breast and other carcinomas, currently receive considerable attention. We have investigated cell-mediated effector mechanisms of HER-2/neu antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::381598fd28104998ccae3bb314ff233b
https://pubmed.ncbi.nlm.nih.gov/9044847
https://pubmed.ncbi.nlm.nih.gov/9044847
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(2)
A bispecific fusion protein (H22-EGF) that binds simultaneously to the epidermal growth factor receptor (EGF-R) and to the high affinity receptor for the Fc portion of human IgG, Fc gammaRI (CD64), has been successfully constructed and expressed. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::576b401a8f9ccce8056f3d5e6745585b
https://pubmed.ncbi.nlm.nih.gov/8993006
https://pubmed.ncbi.nlm.nih.gov/8993006
Autor:
M K, Gorny, T, Keler, S, Burda, C, Williams, J L, Gabriel, W M, Mitchell, Y M, Deo, S, Zolla-Pazner
Publikováno v:
Antibiotics and chemotherapy. 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1abe2884c1c825a5ecdcd99ca67cf668
https://pubmed.ncbi.nlm.nih.gov/8726522
https://pubmed.ncbi.nlm.nih.gov/8726522
Autor:
G. M. Gaucher, Y. M. Deo
Publikováno v:
Biotechnology Letters. 5:125-130
Conidia of Penicillium urticae, immobilized in κ-carrageenan beads, were germinated in situ to form a patulin producing cell mass by incubating these beads in a growth supporting medium. When these in situ grown immobilized cells were repeatedly tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4f5567c8806bbb3772d0f99f6ef6d9
https://doi.org/10.1007/bf00132171
https://doi.org/10.1007/bf00132171