Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Y K, Chou"'
Publikováno v:
Journal of Materials Engineering and Performance. 24:3365-3372
The effect of aging treatments on the mechanical properties and microstructures of Ti-15V-3Cr-3Sn-3Al (Ti-15-3) alloy was evaluated using tensile, notched tensile, and J-integral tests. The properties for the one-step aged specimens (371 to 648 °C f
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture. 220:1663-1671
Fused deposition modelling (FDM) is a layer-manufacturing technology that has been widely used for rapid prototyping applications in product design and development. Owing to the intensive energy, rapid cooling, and phase changes, parts made by FDM an
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture. 218:1647-1655
This study experimentally investigated the attainable hardness and hardened depth at the part surfaces in steel machining with large tool wear, 1-2mm flank wear-land width. Hot-rolled AISI 4340 steel bars were turned on a lathe using ceramic inserts
Publikováno v:
CIRP Annals. 45:77-82
Topography of surfaces produced in finish hard turning using cubic boron nitride (CBN) tools is affected by a large number of factors including tool wear and the mechanics of the chip formation process. This paper shows first that tool wear rates are
Autor:
Y K Chou, W J Morrison, A D Weinberg, R Dedrick, R Whitham, D N Bourdette, G Hashim, H Offner, A A Vandenbark
Publikováno v:
The Journal of Immunology. 152:2520-2529
The biased expression of V beta 5.2 and V beta 6.1 by T cells specific for myelin basic protein (BP) has led to our use of TCR peptides from these V gene sequences to induce anti-TCR immunity in patients with multiple sclerosis (MS). Injection of V b
Autor:
D N Bourdette, R H Whitham, Y K Chou, W J Morrison, J Atherton, C Kenny, D Liefeld, G A Hashim, H Offner, A A Vandenbark
Publikováno v:
The Journal of Immunology. 152:2510-2519
Immunization with disease-associated TCR V region peptides is an effective treatment for experimental autoimmune encephalomyelitis. Myelin basic protein-specific T cells, which induce experimental autoimmune encephalomyelitis in many animal strains,
Autor:
A A, Vandenbark, N, Culbertson, T, Finn, D, Barnes, A, Buenafe, G G, Burrows, S, Law, Y K, Chou, H, Offner
Publikováno v:
Critical reviews in immunology. 20(1)
The major function of the T-cell receptor is to confer antigen specificity to T cells. However, nascent TCR proteins that are not assembled into functional heterodimers may be processed and displayed with self MHC molecules on the T-cell surface, and
Autor:
D N, Bourdette, Y K, Chou, R H, Whitham, J, Buckner, H J, Kwon, G T, Nepom, A, Buenafe, S A, Cooper, M, Allegretta, G A, Hashim, H, Offner, A A, Vandenbark
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(2)
Vaccination with synthetic TCR peptides from the BV5S2 complementarity-determining region 2 (CDR2) can boost significantly the frequency of circulating CD4+ peptide-specific Th2 cells in multiple sclerosis (MS) patients, with an associated decrease i
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Autor:
Y K, Chou, A D, Weinberg, A, Buenafe, D N, Bourdette, R, Whitham, J A, Kaleeba, I F, Robey, D G, Kavanagh, H, Offner, A A, Vandenbark
Publikováno v:
Journal of neuroscience research. 45(6)
HLA-DR2+ patients with multiple sclerosis (MS) that respond to vaccination with TCR V beta 5.2-38-58 peptides have increased frequencies of TCR peptide-specific T cells, reduced frequencies of myelin basic protein (MBP)-specific T cells, and a better