Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Y Grace Chen"'
Autor:
Alexis S Bailey, Pedro J Batista, Rebecca S Gold, Y Grace Chen, Dirk G de Rooij, Howard Y Chang, Margaret T Fuller
Publikováno v:
eLife, Vol 6 (2017)
The switch from mitosis to meiosis is the key event marking onset of differentiation in the germline stem cell lineage. In Drosophila, the translational repressor Bgcn is required for spermatogonia to stop mitosis and transition to meiotic prophase a
Externí odkaz:
https://doaj.org/article/c1bb0fbf955f4358a4ae2280819dbc35
Autor:
Roberta Piras, Emily Y. Ko, Connor Barrett, Marco De Simone, Xianzhi Lin, Marina T. Broz, Fernando H. G. Tessaro, Mireia Castillo-Martin, Carlos Cordon-Cardo, Helen S. Goodridge, Dolores Di Vizio, Mona Batish, Kate Lawrenson, Y. Grace Chen, Keith Syson Chan, Jlenia Guarnerio
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Circular RNAs can contribute to tumour progression. Here the authors show that two circular RNAs, circCsnk1g3 and circAnkib1 promote sarcoma growth by controlling the expression of interferon related genes and pro-inflammatory factors in sarcoma cell
Externí odkaz:
https://doaj.org/article/ce63810cc8a74cdea3778e236afde9f9
Autor:
Justin Tai, Y Grace Chen
Publikováno v:
Journal of Molecular Cell Biology.
Circular RNAs (circRNAs) are single-stranded RNAs that are covalently closed and lack free ends. While relatively little is known about the roles of circRNAs in innate immunity, several studies suggest that endogenous circRNAs are immunosuppressive i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::443149c4caffec76955e47d7c8d5d766
https://doi.org/10.1093/jmcb/mjad002
https://doi.org/10.1093/jmcb/mjad002
Autor:
Lichong Yan, Y. Grace Chen
Publikováno v:
Trends Biochem Sci
Circular RNAs (circRNAs) are a diverse class of RNAs with varying sizes, cellular abundance, and biological functions. Investigations from the past decade have revealed that circRNAs are ubiquitously found in eukaryotes and have defined the different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de04e7353186a155eafe827877c8d542
https://doi.org/10.1016/j.tibs.2020.08.006
https://doi.org/10.1016/j.tibs.2020.08.006
Autor:
Y Grace Chen, Sun Hur
Publikováno v:
Nat Rev Mol Cell Biol
Double-stranded RNA (dsRNA) is associated with most viral infections - it either constitutes the viral genome (in the case of dsRNA viruses) or is generated in host cells during viral replication. Hence, nearly all organisms have the capability of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f918a4fdc6d14475c716b7beaaeacee3
https://pubmed.ncbi.nlm.nih.gov/34815573
https://pubmed.ncbi.nlm.nih.gov/34815573
Autor:
Esen Sefik, Rihao Qu, Caroline Junqueira, Eleanna Kaffe, Haris Mirza, Jun Zhao, J. Richard Brewer, Ailin Han, Holly R. Steach, Benjamin Israelow, Holly N. Blackburn, Sofia Velazquez, Y. Grace Chen, Stephanie Halene, Akiko Iwasaki, Eric Meffre, Michel Nussenzweig, Judy Lieberman, Craig B. Wilen, Yuval Kluger, Richard A. Flavell
Publikováno v:
bioRxiv
Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine production, viral RNA, and sustained interferon (IFN) response all of which are recapitulated and required for pathology in the SARS-CoV-2 infected MISTRG6-hACE2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106c3ec8c6620543b3c1376ecd6d43ee
https://doi.org/10.1101/2021.09.27.461948
https://doi.org/10.1101/2021.09.27.461948
Autor:
Prisca Obi, Y. Grace Chen
Publikováno v:
Methods
Circular RNAs (circRNAs) are a novel class of RNAs distinguished by their single-stranded, covalently-closed topology. Although initially perceived as rare byproducts of aberrant splicing, circRNAs are now recognized as ubiquitously expressed and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c77f3fd2166d97201c6001c68b23c05
https://europepmc.org/articles/PMC8670866/
https://europepmc.org/articles/PMC8670866/
Autor:
Roberta Piras, Emily Y. Ko, Connor Barrett, Marco De Simone, Xianzhi Lin, Marina T. Broz, Fernando H. G. Tessaro, Mireia Castillo-Martin, Carlos Cordon-Cardo, Helen S. Goodridge, Dolores Di Vizio, Mona Batish, Kate Lawrenson, Y. Grace Chen, Keith Syson Chan, Jlenia Guarnerio
Publikováno v:
Nature communications. 13(1)
Exonic circular RNAs (circRNAs) produce predominantly non-coding RNA species that have been recently profiled in many tumors. However, their functional contribution to cancer progression is still poorly understood. Here, we identify the circRNAs expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa6a78f647e9d3053c766abece47984
https://pubmed.ncbi.nlm.nih.gov/36433954
https://pubmed.ncbi.nlm.nih.gov/36433954
Autor:
Lichong Yan, Y. Grace Chen
Publikováno v:
Cell. 183(1)
Circular RNAs (circRNAs) have emerged as key regulators of a wide variety of biological processes, but the roles of mitochondrial circRNAs are largely unknown. In this issue of Cell, Zhao et al. (2020) reveal that mitochondrial DNA-encoded circRNAs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cce20a4f489f7169f7b20ffafaa9cf3
https://pubmed.ncbi.nlm.nih.gov/32931733
https://pubmed.ncbi.nlm.nih.gov/32931733
Autor:
Isabella Li, Y. Grace Chen
Publikováno v:
Curr Opin Immunol
The proper function of the innate immune system depends on an intricate network of regulation that promotes effective responses to pathogens while avoiding autoimmunity. Circular RNAs (circRNAs), a class of RNAs that lack 5' and 3' ends, have emerged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162873b47f98a35d013d2a25eecbf522
https://pubmed.ncbi.nlm.nih.gov/33176221
https://pubmed.ncbi.nlm.nih.gov/33176221