Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Y E, Miller"'
Publikováno v:
Seminars in Oncology. 49:254-260
Lung cancer (both adenocarcinoma and squamous cell) progress through a series of pre-malignant histologic changes before the development of invasive disease. Each of these carcinogenic cascades is defined by genetic and epigenetic alterations in pulm
Autor:
R L, Keith, Y E, Miller, R M, Gemmill, H A, Drabkin, E C, Dempsey, T C, Kennedy, S, Prindiville, W A, Franklin
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
Lung carcinogenesis is assumed to be a multistep process, but detailed understanding of the sequential morphological and molecular changes preceding invasive lung cancer remains elusive. To better understand early lung carcinogenesis, we initiated a
Publikováno v:
Pediatric pulmonology. 26(5)
Compared to normal infants and children, there are increased numbers of neuroendocrine cells with bombesin-like peptide (BLP) immunostaining in the lungs of infants and children with bronchopulmonary dysplasia (BPD) and cystic fibrosis (CF). However,
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(11)
Many lung cancers are stimulated by an autocrine/paracrine system of neuroendocrine peptide hormones. Attempts to block this autocrine growth pathway by interactions with specific ligand-receptor binding using monoclonal antibodies and peptide-specif
Autor:
C J, Gallione, D J, Klaus, E Y, Yeh, T T, Stenzel, Y, Xue, K B, Anthony, K A, McAllister, M A, Baldwin, J N, Berg, A, Lux, J D, Smith, C P, Vary, W J, Craigen, C J, Westermann, M L, Warner, Y E, Miller, C E, Jackson, A E, Guttmacher, D A, Marchuk
Publikováno v:
Human mutation. 11(4)
Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant disorder characterized by multisystemic vascular dysplasia and recurrent hemorrhage from the sites of vascular lesions. Two genes have been identified for HHT. Endoglin, a TGF-beta
Publikováno v:
Genes, chromosomescancer. 21(4)
Small cell lung cancer (SCLC) cell lines and tumors invariably exhibit loss of heterozygosity (LOH) or, in rare cases, homozygous deletions involving part or all of chromosome arm 3p, suggesting the presence of 1 or more tumor-suppressor genes in thi
Autor:
A J, Cohen, R A, Skidgel, L B, Gilman, J K, Black, P A, Bunn, B, Helfrich, W A, Franklin, Y E, Miller
Publikováno v:
Chest. 111
Autor:
T C, Kennedy, S P, Proudfoot, W A, Franklin, T A, Merrick, G, Saccomanno, M E, Corkill, D L, Mumma, K E, Sirgi, Y E, Miller, P G, Archer, A, Prochazka
Publikováno v:
Cancer research. 56(20)
Advances in the understanding of lung cancer biology have led to observations that specific genetic changes occur in premalignant dysplasia. These observations have occurred predominantly in molecular studies of resected lung tumors and consequently,
Autor:
A J, Cohen, P A, Bunn, W, Franklin, C, Magill-Solc, C, Hartmann, B, Helfrich, L, Gilman, J, Folkvord, K, Helm, Y E, Miller
Publikováno v:
Cancer research. 56(4)
Neutral endopeptidase (NEP; CALLA, CD10, EC 3.4.24.11) is a cell surface endopeptidase that hydrolyses bioactive peptides, including the bombesin-like peptides, as well as other neuropeptides. Bombesin-like peptides and other neuropeptides are autocr
Publikováno v:
Journal of inflammation. 45(4)
Acute inflammatory lung injury is a common clinical occurrence following blood loss and trauma, and is characterized by massive neutrophil infiltration into the lung. In order to better examine cell trafficking that may contribute to lung injury in t